molecular genetics Flashcards

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1
Q

centromere

A

point where two chromatids are linked and where the microtubules attach

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2
Q

telomere

A

region of repetitive nucleotide sequences at the end of each chromatid

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3
Q

chromatid

A

one copy of a duplicated chromosome, generally joined to another copy by centromere

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4
Q

genes

A

small segment of DNA where its specific nucleotide sequence codes for a polypeptide with a specific amino acid sequence

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5
Q

nucleotide

A

made up of one phosphate group, one pentose sugar and one nitrogenous base

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6
Q

pentose sugar

A

rna: ribose sugar
dna: deoxyribose sugar

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7
Q

nitrogenous base

A

DNA: Adenine, Guanine Cytosine, Thymine
RNA: Adenine, Guanine, Cytosine, Uracil

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8
Q

structure of DNA

A
  1. two polynucleotide chains wound around each other to form double helix
  2. each strand has a sugar phosphate backbone with nitrogenous bases projected at right angles
  3. nucleotides held together by strong covalent phosphodiester linkages
  4. polynucleotide strands are antiparallel, one runs in the 5’ to 3’ direction, the other in the 3’ to 5’ direction
  5. polynucleotide strands held together by hydrogen bonds between nitrogenous bases on opposite strands
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9
Q

complementary base pairing

A

phenomenon where each type of nitrogenous base on one strand forms hydrogen bonds with a different type of base on the opposite strand

cytosine + guanine (3 H bonds)

adenine + thymine ( 2 H bonds)

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10
Q

central dogma theory

A

flow of genetic information from dna through rna to protein

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11
Q

transcription

A

process where a gene is copied to form piece of messenger rna

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12
Q

translation

A

process where genetic information on the messenger rna is read by a ribosome to synthesize a polypeptide

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