MOLECULAR DIAGNOSTIC TOOLS

Question 1

branch of clinical diagnostics that utilizes genetic material (DNA or RNA) in disease diagnosis

Answer 1

MOLECULAR DIAGNOSTIC

Question 2

analyze biological markers in the genome and proteome, and how their cells express their genes as proteins, applying molecular biology to medical testing

Answer 2

MOLECULAR DIAGNOSTIC

Question 3

analysis of nucleic acids & proteins

Answer 3

Molecular Pathology

Question 4

patterns of inheritance

Answer 4

Gregor Mendel (1866)

Question 5

genes were

associated with chromosomes

Answer 5

Thomas Morgan (1910)

Question 6

initial finding that DNA was the transmittable genetic material

Answer 6

Frederick Griffith (1928) and Oswald Avery, Colin MacLeod & Maclyn McCarty (1944) -

Question 7

quantity of guanine equals the quantity of cytosine, & the quantity of adenine is similar to the amount of thymine (Chargaff rule)

Answer 7

Erwin Chargaff (1940s)

Question 8

X-ray diffraction image “photo 51”

Answer 8

Franklin & Maurice Wilkins (1952)

Question 9

double helix structure of the DNA

Answer 9

James Watson & Francis Crick (1953)