Molecular biology Flashcards
1
Q
label for mets and choriocarcinoma and embryonal cell carcinomas
A
hCG
2
Q
Abnormally high in gravid women w a fetus w open neural defect.
A
alfa fetoprotein
3
Q
what tumor has typically -7/+10 ?
A
Glioblastoma
4
Q
What tumor is H3 K27 alterations typical?
A
- pediatric type diffuse high grade glioma
- diffuse midline glioma
5
Q
What tumor is H3 G34 mutant?
A
Typical for pediatric type diffuse high grade glioma
6
Q
What tumor is typically H3wt IDHwt?
A
Pediatric type diffuse high grade glioma, H3wt, IDHwt.
7
Q
In what tumor is MYB and MYBL1 alterations typically found?
A
Pediatric type low grade glioma
8
Q
what tumor show MAPK pathway alterations?
A
Pediatric type diffuse low grade grade gliomas