Molecular And Cellular Term 1 Flashcards

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1
Q

What is the difference between Eukaryote and prokaryote

A

Eukaryote is linear

Prokaryote is singular

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2
Q

How big is the genomes in the prokaryotes and eukaryotes

A

Large

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3
Q

Why does bacteria fold into their circular shape

A

This enables the DNA to fit in the cell

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4
Q

What does eukaryotes structure defined as

A

A double helix is packed into another structure known as chromatin

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5
Q

What is chromatin

A

Chromatin is dna that is specialized positive charged proteins known as histones which enables DNA to be bent

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6
Q

What are the functional implications of higher order DNA packaging and chromatin structure?

A
  1. Stores our genetic code – information/instructions to make proteins
  2. . Needs to be able to be accurately replicated –code is passed on from parental to daughter cells
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7
Q

What must be done for DNA to be replicated

A

It must be Condensed

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8
Q

What is transcription

A

DNA strand separation, one strand serves as a template for RNA synthesis

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9
Q

What does ATP modelling use

A

Energy to slide or displace nucleosomes

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10
Q

What is the chromatin structure like

A

Dynamic

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11
Q

From which point of regulation does the information occur

A

from the point of DNA to the protein

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12
Q

What is gene transcription

A

Transcription requires unwinding of DNA double helix and strand separation, one DNA strand used a template for the synthesis of an RNA transcript

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13
Q

What is transcription catalzyed by?

A

A RNA polymerase

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14
Q

What is a sig factor

A

is a protein needed for initiation of transcription in bacteria. It is a bacterial transcription initiation factor that enables specific binding of RNA polymerase to gene promoters.

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15
Q

What does operon mean

A

Operon means a group functionally related genes transcribe from one promoter

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16
Q

What are operons more common in

A

Bacteria and enable co ordinate

17
Q

is each gene transcribed groupoid or invidual

A

Invidual

18
Q

Does regulatory control of transcription occur in both?

A

YES

19
Q

What is needed for regulatory control

A

Large compartments which are cellular

20
Q

What happens between two healthy cells?

A

In normal, healthy tissue there is always a balance (homeostasis) between the production of new cells and the number of cells that die.

21
Q

What is a villus made up of?

A

Each villus is made of single layer of epithelial of cells.

22
Q

What form of cell to cell signalling

A

Pancrine

23
Q

What is Invasion

A

spread of cancer from one organ to another organ in the body is one of the hallmarks of cancer

24
Q

What does cancer require to develop

A

single cell the accumulation of a number of spontaneous mutations in a specific subset of genes that together confer the key traits or hallmarks of cancer

25
Q

What does genetic heterogeneity

A

The presence of a variety of genetic defects which cause the same disease, often due to mutations at different loci on the same gene,