Molds

Question 1

What are superficial mycoses

Answer 1

Malasezzia

Trichosporon

Question 2

What are cutaneous molds?

Answer 2

Microsporum
Trichophyton
Epidermophyton

Question 3

What is common component of mold cell wall?

Answer 3

Ergosterol

Question 4

How do you diagnose mold under microscope?

Answer 4

KOH prep, look for hyphae
Calcoflour white causes hyphae to flouresce
India ink
Methenamine silver

Question 5

How do you culture molds?

Answer 5

Sabourauds Agar (inhibits bacterial growth)

Question 6

What are important antifungal agents?

Answer 6

Azoles - inhibit ergosterol synthesis
Polyenes (amphoteracin) - Bind ergosterol and make pores
Echinocandins - inhibit synthesis of b- glucan and blocks cell wall

Question 7

Why are polyenes bad to use?

Answer 7

Renal toxicity

Question 8

What are important subcutaneous mycoses?

Answer 8

Sporotrichosis
Chromoblastomycosis
Eumycotic Mycetoma
(All rare, Introduced traumatically, typically dont spread to far organs)

Question 9

Sporotrichosis

Answer 9

think rosebushes

common in gardeners

Question 10

Chromomycosis

Answer 10

Causes colored warty growths
Look for medlar bodies
Treat orally, surgical romoval can lead to recurrence

Question 11

Eumycotic mycetoma

Answer 11

Really bad and hard to treat
Looks like sandy granules
frequently cured by amputation