MolBio17 - 13

Question 1

What is the rate of change of nucleotide sequence in ape/man?

Answer 1

1% every 10 million years

Question 2

What is parsimony?

Answer 2

Selection of the simplest model of evolutionary inheritance

Question 3

What is convergent evolution?

Answer 3

Arising of mutations twice, by chance

Question 4

How many vertebrate FGFs are there?

Answer 4

22

Question 5

How many clusters based on protein seuqnce alignment, to vertebrate FGF’s fall into?

Answer 5

4

Question 6

What is a paralogue?

Answer 6

New copies of genes that arise in the genome

Question 7

What part of a paralogue can change easily?

Answer 7

Enhancer

Question 8

What is interesting about the expression of regulatory genes?

Answer 8

Can correlate to morphological changes

Question 9

What are genes that control whole gene networks called?

Answer 9

Master regulatory genes

Question 10

What is evolutionary robustness?

Answer 10

Ability of developing embryo to adapt readily to changes in expression, i.e. ectopic organs

Question 11

What does Dlx do?

Answer 11

Specifies leg precursor cells in fly embryos

Question 12

What does Ubx do?

Answer 12

Respresses Dlx, usually in the abdomen

Question 13

What is the difference between crustacean and fly Ubx?

Answer 13

Crustacean has an anti-repression complex