Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

flashcards > mol bio proteins > Flashcards

mol bio proteins Flashcards

1
Q

DNA polymerase: the palm

A

site of catalysis, binding site for 2 divalent metal ions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DNA polymerase: the fingers

A

clamps down on incoming dNTPs and binds them with template strand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DNA polymerase: the thumb

A

holds onto synthesized double helix, promotes processivity, DNA binding element

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

RNAP

A

transcribes template DNA to RNA, binds to promoter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

RNAP β’

A

largest unit containing part of active center responsible for RNA synthesis, some determinants for nascent RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

RNAP β

A

second largest unit containing the rest of the active center, rest of determinants for interactions with DNA and nascent RNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

RNAP α

A

determinants for assembly of RNAP, interaction with promoter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rho

A

ring hexameric complex surrounding nascent RNA, ATPase activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

TRCF

A

promotes dissociation when RNAP stalls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

RNA Pol I

A

synthesizes pre-rRNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

RNA Pol II

A

synthesizes precursors of mRNAs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

RNA Pol III

A

synthesizes tRNAs, rRNAs, and other small RNAs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

TFIID

A

general transcription factor protein complex. binds to TATA box and contains TBP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

TBP

A

binds DNA to facilitate other TF binding, binds other proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

TFIIH

A

uses ATP to unwind/melt double helix

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Mediator complex

A

allows proteins bound far away to affect transcription

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

RNAP ω

A

facilitates assembly of RNAP and stabilizes it

18
Q

RNAP σ^70

A

acts in initiation and elongation to induce transcription pause

19
Q

RNAP σ^H

A

initiation factors that promote attachment of RNAP to specific initiation sites

20
Q

elongation factors

A

proteins involved in promoting region, helps maintain processivity of RNAP, assists in splicing

21
Q

CstF

A

recognizes second polyadenylation sequence element

22
Q

CPSF

A

recognizes AAUAAA signal in pre-mRNA and interacts with other proteins

23
Q

PolyA Polymerase (PAP)

A

catalyzes incorporation of adenine into 3’ terminal of RNA, adds PolyA tail to RNA

24
Q

Spliceosome complex

A

precisely removes introns from pre-mRNA to generate mature mRNA

25
Q

snRNPs

A

removes introns from pre-mRNA

26
Q

U1

A

binds to 5’ splice site by complementing base pairing

27
Q

U2

A

base pairs with sequences at intron branch site and associates with U6

28
Q

U4

A

associates with U6 until U6 is needed and dissociates

29
Q

U5

A

associates with last nucleotide of upstream exon and first nucleotide of upstream intron and positions them together

30
Q

U6

A

binds to 5’ splice site by base pairing and associates with U2

31
Q

Branch point binding protein (BBP)

A

interacts directly with mRNA, aides in splice site recognition

32
Q

Aminoacyl-tRNA synthetase

A

catalyzes charging reaction that links specific amino acids to tRNA molecules

33
Q

Ribosomal large subunit

A

two RNA strands, catalyzes chemical events in protein synthesis, peptide bond formation

34
Q

Ribosomal small subunit

A

decodes genetic information, formation of initiation complex

35
Q

Initiation factor 1

A

blocks elongator tRNA binding at A-site

36
Q

Initiation factor 2

A

transports initiator tRNA to P-site

37
Q

Initiation 3

A

checks P-site codon-anticodon pairing and rejects incorrect complexes

38
Q

EF-TU

A

catalyzes binding of aa-tRNA to A-site of ribosome, G-protein

39
Q

Class I release factors

A

recognize stop codons (UUA and UAG), bind to A-site of ribosome

40
Q

Class II release factors

A

enhances activity of class II release factors, recognizes UGA and UAA codons

flashcards (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions