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Advanced Pharmacology 533 > Modules 7-8 Antibiotics > Flashcards

Modules 7-8 Antibiotics Flashcards

1
Q

Which ABTs for mild cellulitis in the immunocompromised, DM, vasc insufficient, etc?

  • Amox/TR-Clav (Augmentin)
  • Levofloxacin + clindamycin
  • moxifloxacin
A

-

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2
Q

Which ABTs for mild cellulitis in the immunocompromised, DM, vasc insufficient, etc?

A
  • Amox/TR-Clav (Augmentin)
  • Levofloxacin + clindamycin
  • moxifloxacin
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3
Q

Which ABTs for mod-severe cellulitis in the immunocompromised, DM, vasc insufficient, etc?

A
  • Vancomycin
  • daptomycin
  • telavancin
  • linezolid +B-lactam
  • carbapenem
  • ceftaroline with clindamycin or metronidazole
  • ceftazidime with clindamycin
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4
Q

Which ABTs for mod-severe cellulitis in the immunocompromised, DM, vasc insufficient, etc?

  • Vancomycin
  • daptomycin
  • telavancin
  • linezolid +B-lactam
  • carbapenem
  • ceftaroline with clindamycin or metronidazole
  • ceftazidime with clindamycin
A

-

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5
Q

Which ABTs for mild cellulitis in previously healthy people?

  • dicloxacillin
  • cephalexin
  • clindamycin
A

-

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6
Q

Which ABTs for mild cellulitis in previously healthy people?

A
  • dicloxacillin
  • cephalexin
  • clindamycin
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7
Q

Which ABTs for mod-severe cellulitis in previously healthy people?

A
  • nafcillin
  • cefazolin
  • clindamycin
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8
Q

Which ABTs for mod-severe cellulitis in previously healthy people?

  • nafcillin
  • cefazolin
  • clindamycin
A

-

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9
Q

If CA-MRSA is suspected or there’s an allergy to PCN, treat mild cellulitis in previously healthy adults with:

  • clindamycin
  • SMZ/TMP
  • doxycycline
A

-

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10
Q

If CA-MRSA is suspected or there’s an allergy to PCN, treat mod-severe cellulitis in previously healthy adults with:

  • Vancomycin
  • linezolid
  • daptomycin
  • ceftaroline
  • telavancin

(Regarding cellulitis.)

A

-

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11
Q
  • Vancomycin
  • linezolid
  • daptomycin
  • ceftaroline
  • telavancin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mod-severe cellulitis in previously healthy adults when CA-MRSA is suspected or there’s an allergy to penicillin.

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12
Q
  • clindamycin
  • SMZ/TMP
  • doxycycline

What do these ABTs treat?

(Regarding cellulitis.)

A

Mild cellulitis in previously healthy adults when CA-MRSA is suspected or there’s an allergy to penicillin.

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13
Q
  • nafcillin
  • cefazolin
  • clindamycin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mod-severe cellulitis in previously healthy adults.

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14
Q
  • dicloxacillin
  • cephalexin
  • clindamycin

What do these ABTs treat?

(Regarding cellulitis.)

A

Mild cellulitis in previously healthy adults.

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15
Q

Bacterium most common causing uncomplicated cellulitis?

A

S. pyogenes (GAS)

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16
Q
  • Clindamycin
  • TMP/SMZ
  • doxycycline
  • minocycline
  • linezolid
  • tedizolid
  • delafloxacin

These ABTs treat what?

A

MRSA in adults

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17
Q

Regarding hyperse_________, avoid penicillins or cephalosporins in patients with a history of it.

A

hypersensitivity

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18
Q

Avoid these ABTs in children:

  • cycl___s
  • quino____s
A
  • cyclines
  • quinolones
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19
Q

There are drug interactions between quinol___s and Ca, Mg, iron, etc.

A

quinolones

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20
Q

If hypersensitive to an ABT like PCN, cephalosporins, and carbapenems, you can use an alter______ ABT.

A

alternative

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21
Q

Antibiotic of choice for animal bites: (Aug______)

A

Amoxicillin-Clavulanate (Augmentin)

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22
Q

An alternative antibiotic empiric regimen for animal bites. One of the 1st group and one of the 2nd group.

1st: (ONE OF THESE)
- doxycycline
- TMP/SMZ
- penicillin
- cefuroxime
- moxifloxacin

AND

2nd: (ONE OF THESE)
- metronidazole
- clindamycin

A

-

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23
Q

Is doxycycline and metronidazole OK as an alternative treatment for animal bites?

[Y/N Q]

A

Y

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24
Q

Is penicillin and clindamycin OK as an alternative treatment for animal bites?

[Y/N Q]

A

Y

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25
Q

Metronidazole or clindamycin are OK options for the SECOND part of the alternative combination in treating animal bites.

A

-

26
Q

Tetracyclines should be avoided in children.

A

-

27
Q

Tetrac_______ should be avoided in children.

A

Tetracyclines

28
Q

S. pyogenes and S. aureus are most commonly involved in impetigo in children.

A

-

29
Q

Treatment for impetigo include:

  • antistaphylococcal penicillins (like dicloxacillin)
  • 1st gen cephalosporins (like cephalexin)
A

-

30
Q

Treatment options for impetigo include:

  • dicloxac_____
  • cephal____
A
  • dicloxacillin
  • cephalexin
31
Q

For uncomplicated LUTIs, use:

  • nitrofurantoin
  • SMZ/TMP
A

-

32
Q

For uncomplicated LUTIs, use:

A
  • nitrofurantoin
  • SMZ/TMP
33
Q

For uncomplicated LUTIs, use:

  • nitrofur______
  • SM_/TM_
A
  • nitrofurantoin
  • SMZ/TMP
34
Q

For complicated LUTIs, use:

  • cefpodoxime
  • SMZ/TMP
  • quinolone
A

-

35
Q

For complicated LUTIs, use:

A
  • cefpodoxime
  • SMZ/TMP
  • quinolone
36
Q

For complicated LUTIs, use:

  • cefpod_____
  • SM_/TM_
  • quino____
A
  • cefpodoxime
  • SMZ/TMP
  • quinolone
37
Q

Antibiotic agents of choice for asymptomatic bacteriuria:

  • beta-lactams
  • nitrofurantoin
  • fosfomycin
A

-

38
Q

Antibiotic agents of choice for asymptomatic bacteriuria:

A
  • beta-lactams
  • nitrofurantoin
  • fosfomycin
39
Q

Antibiotic agents of choice for asymptomatic bacteriuria:

  • beta-lact___
  • nitrofur______
  • fosfomy___
A
  • beta-lactams
  • nitrofurantoin
  • fosfomycin
40
Q

ABTs for asymptomatic bacteriuria and cystitis in pregnancy:

  • nitrofurantoin
  • amoxicillin
  • amoxicillin-clavulanate
  • cephalexin
  • cefpodoxime
  • fosfomycin
  • TMP/SMZ
A

-

41
Q

These ABTs are for…?

  • nitrofurantoin
  • amoxicillin
  • amoxicillin-clavulanate
  • cephalexin
  • cefpodoxime
  • fosfomycin
  • TMP/SMZ
A

ABTs for asymptomatic bacteriuria and cystitis in pregnancy.

42
Q

ABTs for asymptomatic bacteriuria and cystitis in pregnancy:

A
  • nitrofurantoin
  • amoxicillin
  • amoxicillin-clavulanate
  • cephalexin
  • cefpodoxime
  • fosfomycin
  • TMP/SMZ
43
Q

Don’t use fosfomy___ for asymptomatic bacteriuria/cystitis IF pyelonephritis is suspected, because it does not achieve therapeutic levels in the kidneys.

A

Fosfomycin

44
Q

Don’t use TM_/SM_ during the first trimester or at term.

A

TMP/SMZ

45
Q

Don’t use nitrofuran____ during the first trimester or at term.

A

Nitrofurantoin

46
Q

Don’t use nitrofuran____ for asymptomatic bacteriuria/cystitis IF pyelonephritis is suspected, because it does not achieve therapeutic levels in the kidneys.

A

Nitrofurantoin

47
Q

Regarding ABTs for asymptomatic bacteriuria and cystitis in pregnancy:

Amoxi______ resistance may limit its utility among gram-negative pathogens.

A

Amoxicillin

48
Q

For uncomplicated pyelonephritis, use:

  • SMZ/TMP
  • quinolones
A

-

49
Q

For uncomplicated pyelonephritis, use:

A
  • SMZ/TMP
  • quinolones
50
Q

For uncomplicated pyelonephritis, use:

  • SM_/TM_
  • quino_____
A
  • SMX/TMP
  • quinolones
51
Q

Primary regimen for uncomplicated bacterial prostatitis with risk of STD:

1) Ceftriaxone x1 dose OR cefixime x1 dose

THEN:

2) Doxycycline BID x10 days

A

-

52
Q

Primary regimen for uncomplicated bacterial prostatitis with risk of STD:

1) Ceftria____ x1 dose OR cefix___ x1 dose

THEN:

2) Doxycy_____ BID x10 days

A

1) Ceftriaxone x1 dose OR cefixime x1 dose

THEN:

2) Doxycycline BID x10 days

53
Q

Primary regimen for uncomplicated bacterial prostatitis with risk of STD:

A

1) Ceftriaxone x1 dose OR cefixime x1 dose

THEN:

2) Doxycycline BID x10 days

54
Q

Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD:

  • Levofloxacin OR ciprofloxacin x10-14 days

OR

  • SMZ/TMP BID x10-14 days
A

-

55
Q

Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD:

A
  • Levofloxacin OR ciprofloxacin x10-14 days

OR

  • SMZ/TMP BID x10-14 days
56
Q

Primary regimen for uncomplicated bacterial prostatitis with LOW risk of STD:

  • Levof_______ OR ciprof_______ x10-14 days

OR

  • SM_/TM_ BID x10-14 days
A
  • Levofloxacin OR ciprofloxacin x10-14 days

OR

  • SMZ/TMP BID x10-14 days
57
Q

Use of adjunctive uroselective alpha-adrenergicantagonists should be considered to reduce symptomatology of bacterial prostatitis. These symptoms include poor urinary stream, hesitancy, etc.

These meds include:

  • tamsulosin
  • alfuzosin
  • silodosin
A

-

58
Q
  • tamsulosin
  • alfuzosin
  • silodosin

These are adjunctive uroselective alpha-adrenergicantagonists that help with the symptoms of bacterial prostatitis (hesitancy, poor urinary stream, etc).

A

-

59
Q

SMZ/TMP also known as co-trimoxazole

A

-

60
Q

co-trimoxazole =

A

SMZ/TMP

61
Q

SMZ/TMP =

A

co-trimoxazole

Advanced Pharmacology 533 (46 decks)

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