Module B Flashcards
what is a voluntary movement
Voluntary movement is the expression of thought through action. Virtually all areas of the central nervous system are involved in this process
name the three motor system generates
reflexive
- can be carried out automatically without conscious control
rhythmic
- can be carried without conscious country control of all aspects of the movement such as walking, breathing
voluntary
- Voluntary movements are goal-directed and improve with practice as a result of feedback and feedforward mechanisms.
what is the central nervous system
it controls most of the functions of the body and mind.
it consists of two parts which is the brain and the spinal cord
how the voluntary movement is being controlled by the previous system?
the brain controls voluntary arm and hand movement by sending decreasing motor commands to the pattern generating circuitry in the spinal cord.
name the major components of the motor system?
1- cerebral cortex and descending pathways
= Are groups of myelinated nerve fibers that carry motor information from the brainstem to the effector’s muscles by the spinal cord.
2- basal ganglia (nuclei)
= involved in initiating movement and postural adjustment
3- cerebellum
= properly compares planned action to actual action
4- brainstem
= origin of descending brainstem pathways to the spinal cord (expect corticospinal tract)
5- motor neuron and interceurones
= capable of stereotypes reflect behaviors
what are the 3 levels of the hierarchy of motor control
The highest level (planning)
- development of strategies and motor plans to achieve the goal
Middle level (commanding) - the middle-level structures specify the postures and movements needed to carry out the intended action.
The lowest level (execution)
- integration of sensory afferent and decreasing pathways input into the spinal circuits of interneurons.
what is a sensory and motor system
Sensory and Motor Systems is allowing how the brain allows us to see, hear, feel, test and smell
- sensory and motor stem uses information carried y a number of anatomically distinct pathways.
what is somatosensory cortex 1
the mapping of the bodies surface sensation into a structure in the brain is called somatotopy
what is somatosensory cortex 2
providing sensory information required for specific planning invitation and ongoing movement.
what is somatosensory cortex 3
sensory neurons can adapt due to amputation a clinical condition known as phantom limb.
phantom limb is the felling of sensation in limb that has been removed, which it is because the brain continues to get massage form nerves that used to feel for the missing limb
what is motor contex 1
motor homunculus showing the distributions of motor output form the primary motor cortex to different parts of the body.
name each section of motor cortex 2
primary motor cortex
= controles simple features of movement
premotor cortex
= involved in the planning and coordination of movement in response to sensory inputs.
supplementary motor area
= active during the planning and coordinating of internally-guided movement.
what is spinal cord 1
The spinal cord is the link between the brain and the nerves in the rest of the body.
a spinal nerve consists of afferent fibres that entre through the dorsal roots and efferent fibres that exit through the ventral roots
what is spinal cord 2
the motor nuclei of the spinal cord are arranged along a medial-lateral axis according to function
what is a medial motor
medial motor nuclei contain the motor neurons innervating (عصب کشی) axils (زیر بغل) muscles of the neck and back
what is the function of the spinal cord
performs two basic functions
1- the link between brain and body
2- integration (اختلاط) of afferent input and efferent output.
what are afferent input and efferent output?
neurons that receive information from our sensory organs (eyes, skin ) and transmit this input to the central nervous system are called afferent neurons
neurons that send impulses from the central nervous system to your limb and organs are called efferent neurons.
what is plasticity?
the connection in the brain can be modified by experience or injury is plasticity.
can neurons function in isolation?
no, because they are organized into circuits that process specif information
what is Excitation-Contraction Coupling
refers to the series of events linking muscle excitation (the presence of an action potential in muscles fibers) to muscle contraction
= commands for voluntary originate in the brain
= action potential conveyed to skeletal muscle by motor neurons through a neuromuscular junction
what is the neuromuscular junction
it is the synapse between a neuron and muscles is called neuromuscular junction
neuromuscular transmission
is a process that permits the central nervous system to control the movement of muscle in the body.
nerve impulses cause the release of neurotransmitters, acetylcholine (ACh) into the junction between the nerve cell and the muscle cell.
what is the structure of skeletal muscle 1
muscles consist of a number of muscle fibers lying parallel to one and held together by connective tissue.
= Single skeletal muscle cell is known as a muscle fiber (10-100 microns)
what is the structure of skeletal muscle 2
display alternating dark and light giving the appearance of striation
what is the structure of skeletal muscle 3
during muscle contraction, the thin filaments slide over the thick filaments, but the filaments themselves done change the length
what is the structure of skeletal muscle 4
contractile forces are produced by the interaction of the thick and thick filaments
what are the thick filaments consists of
of mycosis molecules, where the thin filaments comprise actin, troponin, and tropomyosin
muscle contraction is produced by
the interaction of the actin and myosin.
what is the role of calcium in the body
strengthening bones and teeth. regulating muscle functioning, such as contraction and relaxation. regulating heart functioning. blood clotting.
the role of calcium
tropomyosin
= covers actin sites blocking interaction that leads to muscles contraction
troponin
= With tropomyosin out of way, actin and myosin bind, interact at cross-bridges, resulting in muscle contraction.
calcium and cross-bridge interaction
the cross bright interaction between actin and myosis brings about muscle contraction of the sliding filament mechanism
what is cross bright
The molecular mechanism, where the myosin and acting myofilaments slide over each other is termed the cross-bridge cycle. During muscle contraction, the heads of myosin myofilaments quickly bind and release in a ratcheting fashion, pulling themselves along the actin myofilament.
T Tubules and Sarcoplasmic Reticulum 1
The sarcoplasmic reticulum is the source of Ca2+that repositions troponin and tropomyosin to permit cross-bridge binding.
what is muscle contraction
Muscle contraction is the activation of tension-generating sites within muscle cells. muscle tension changes but the muscle length remains the same.
stages of muscle contraction
1- Ach (acetylcholine) from the nerve terminal
2- AP generated in muscle fiber and down T-tubule
3- AP (action potential) triggers calcium release from SR
4- calcium binds to troponin moving tropomyosin
5- myosin binds to actin and producing the power stroke
6- calcium (ca2) taken up by SR
7- tropomyosin back to blocking position.
electrical vs, contractile activity
contractile activity far outlasts the electrical activity that initiated it
each axon terminal of a motor neurons forms a
neuromuscular junction with a single muscle fibre.
Signals are passed between the nerve terminal and the muscle by
means of the chemical messenger acetylcholine (ACh).
The ion movement depolarises
the motor endplate, generating a muscle fibre action potential.
Myosin forms the thick filaments whereas the
actin is the main structural component of thin filaments.
§During contraction,
cycles of cross-bridge binding and bending pulls the thin filaments inward.
Calcium is the link between
excitation and contraction.