Module 9: AMS Flashcards

1
Q

etiology of AMS, primary neurologic

A

stroke, seizure (postictal, status, non convulsive, infection (meningoencephalitis, abscess), epidural/subdural hematoma, concussion, hydrocephalus, completed migraine, venous thrombosis, cholesterol or fat emboli, CNS vasculitis, TTP (thrombotic thrombocytopenia purpura)

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2
Q

etiology of AMS, systemic (especially found in elderly)

A
  • cardiac: Sever CHF, HTN encephalopathy
  • pulmonary: decreased PaO2, increased PaCO2
  • GI: liver failure, constipation, Wilson’s
  • Renal: uremia, hypo-/hyper natremia
  • endocrine: decreased glucose, DKA, HHNS, increased Ca, hypo or hyperthyroidism, Addisonian crisis
  • ID: PNA, UTI, sepsis
  • hypo/hyperthermia
  • medicaitons especially opiates & sedatives
  • ETOH & toxins
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3
Q

assessment of AMS

A
  • history: previous/recent illnesses, including underlying dementia or psychiatric disorders, head trauma, medications, drug/alcohol use
  • general PE: signs of trauma, stigmata of liver disease, embolic phenomena, signs of drug use, nuchal rigidity (do not test if concern for trauma/cervical spine injury)
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4
Q

what is confusion (encephalopathy)

A

unable to maintain coherent thought process

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5
Q

what is delirium

A

waxing/waning confusional state w/ additional sympathetic signs

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6
Q

what is drowsiness

A

decreased level of consciousness, but rapid arousal to verbal or noxious stimuli

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7
Q

stupor?

A

impaired arousal to noxious stimuli, but some preserved purposeful movements

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8
Q

coma?

A

sleep-like state of unresponsiveness w/ no purposeful responses to stimuli

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9
Q

delirium vs dementia?

A

delirium:

  • abnormal mental state/not a disease
  • usually due to drug use or life-threatening condition
  • causes: medication, infection, drug use, organ failure, surgery, hospitalization, disease processes, poisons
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10
Q

dementia?

A
  • decline in mental ability severe enough to interfere w/ daily life
  • braid disease not an inevitable outcome of aging
  • Alzheimer’s is most common followed by vascular
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11
Q

features of delirium

A
Onset: acute
course: fluctuating
duration: days-weeks
consciousness: altered
attention: impaired
reversibility: usually
hallucinations: frequent
identifiable causes: frequent
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12
Q

features of dementia:

A

onset: insidious
course: progressive
duration: lifelong
Consciousness: clear
attention: normal
reversibility: rarely
hallucinations: rare
identifiable cause: rare

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13
Q

what’s included in a neuro exam?

A

-observation for spontaneous movements, response to stimuli, papilledema
cranial nerves: eye position at rest, response to visual threat, corneal reflex, facial grimace to nasal tickle, cough/gag
-pupil size and reactivity: pinpoint ->opiates. mid position & fixed -> midbrain lesion. fixed & dilated –>severe anoxic encephalopathy, herniation
-motor response in extremities to noxious stimuli - noting purposeful or posturing
-DTR, babinski response

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14
Q

what is intact oculecephalic

A

doll’s eyes, eye movement opposite head movement. or

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15
Q

what is oculovestibular

A

cold calorics = eye move toward lavaged ear, implies brainstem intact

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16
Q

what are signs of increased ICP

A

HA, vomiting, bradycardia, papilledema, unilateral dilated pupil

17
Q

what is mild brain injury GCS?

A

13 or higher

18
Q

what is moderate brain injury GCS

A

9-12

19
Q

what is severe brain injury

A

< 8

20
Q

what is initial treatment for AMS?

A

-control the airway
-monitor VS, ensure adequate IV access
-immobilization of C spine if concern for cervical trauma
-

21
Q

which comes first, thiamine or dextrose?

A

thiamine 100 mg IV prior to dextrose to prevent exacerbation of wernicke ecephalopathy

22
Q

what do you give for opioid overdose

A

narcan

23
Q

what do you give for benzo overdose

A

flumazenil

24
Q

what do you do if concern for increased ICP?

A

elevated HOB, osmotherapy w/ mannitol, hyperventilation, consider emergent surgical decompression

25
Q

what do you get for diagnostic labs?

A
  • chemistry: lytes, bun/cr, LFT, TSH, ammonia
  • hematology: CBC w/ diff, coags
  • urine: UA & tox
    microbiology: blood & sputum culture, urine cx pending UA
26
Q

what diagnostic imaging?

A

CT head for hemorrhage, tumor, edema, herniation. c spine for fracture, herniation

cxr: r/o pna in elderly

eeg r/o nonconvulsive seizures

mir w w/o contrast in setting of unrevealing CT

27
Q

what diagnostic procedures do you do?

A

LP: note opening pressure and color
csf profile: protein, glucose, cell count (1, 4)
csf gram stain, cultures (bacterial, viral, fungal)
pcrs for HSV, EBC, VZV, CMV
additional panels: lyme, paraneoplastic, cryptococcal and west nile

28
Q

treatment for ams?

A

diagnosis dependent

  • continue supportive measures while delineating potential causes
  • may require intubation for airway protection independent of hypoxia/hypercarbia
  • if infectious etiology suspected may empirically start abx.