Module 9 Flashcards
infection
state of cellular, tissue, and sometimes even organ destruction resulting from invasion by microorganisms
pathogen
disease producing microbe
three necessities for infection to occur
source, susceptible person, transmission
three lines of defenses
skin and mucous membranes, inflammatory response, immune response
types of pathogens
bacteria, viruses, Rickettsiae, mycoplasms, Chlamydiae, fungi, protozoa, helminths
virulence
potency of the pathogen, more virulent, more that it causes severe disease in a large proportion of those exposed to the microbe
infectivity
proportion of exposures needed to cause infection in an individual based on pathogen’s ability to enter, survive in, and multiply in the host
toxigenicity
ability of pathogen to produce harmful toxins that increase host cell and tissue damage
antigenicity
level to which a pathogen is viewed by the host immune system as foreign, More antigenic pathogen, more prominent immune response. Low antigenicity, means it will elude immune mechs and continue to survive in the host
antigenic variability
mechanisms through which pathogens try to evade the immune system (usually mutation), process of eluding human host defenses and is often a result of altering the antigens present within or on surface of microbe
pathogenic defense mechanism
ways in which many pathogens have developed ways to avoid destruction by host, such as through thick protective capsules, which prevent phagocytosis
coinfection
phenomenon of hosting two or more pathogens simnultaneously
superinfection
when an infection arises in addition to one that is already present, often results from compromised host defenses and over proliferation of resident flora