Module 8 - Using genome projects Flashcards
What is a genome?
The entire set of DNA, including all the genes in an organism
What has to be done if an entire genome wants to be translated?
The DNA sequence has to be divided into small fragments and then put back in order
What is a proteome?
An organism is all the proteins that are made by it.
What organism is used in medical research and development?
Bacteria because they don’t contain introns making it easy to determine their proteome
- They can be used to identify protein antigens on the surface of disease-causing bacteria and viruses ca help in the development of vaccines to prevent disease.
Why is it harder to translate the genome of complex organisms?
They contain large sections of non-coding DNA. They also contain complex regulator genes which determine when the genes that code for particular proteins should be switched on or off.
What are sequencing methods?
Identifying bases in a DNA sequence
How has sequencing methods changed?
They were labour intensive, expensive and could only be done on a small scale but now, they are automated, cost-effective and can be done on a large scale. This makes it much quicker to sequence too.
