Module 8 Biology of cancer Cells Flashcards
1
Q
Common Terms in Cancer: Tumor Neoplasm benign Malignant
A
Tumor- abnormal growth, proliferation of cells
Neoplasm: New Growth
Benign tumor/neoplasm- non invasive/non cancerous
Malignant Tumor/Neoplasm: Cancerous
2
Q
Benign: how to tell the difference…
A
Encapsulated Well-differentiated Somewaht normal tissue structure non-invasive Don't spread to lymph/distant locations Slow Growing Rarely mitotic Tissues: "oma" names
3
Q
Malignant: telling the difference
A
More rapid growth Mitotic cells visible Loss of differentation (anaplasia) Irregular size/shape of nucleus Loss of normal tissue structure Capsule lost/ compromised Invasive Spreads to distant sites (metastasis) Cell type "carcinoma or "oma"
4
Q
carcinoma:
A
epithelial derived tumor
vs. papilloma benign
5
Q
adenocarcinoma
A
think adenoids– glands
ductal or glandular derived tumor
vs. adenoma benign
6
Q
sarcoma:
A
connective tissue derived tumor
vs. fibroma, lipoma, osteoma, chondroma are benign tumor
7
Q
lymphoma
A
: lymphatic tissue derived (lymph node, etc)
no benign version
8
Q
leukemia
A
: blood cell derived
9
Q
leiomyosarcoma:
A
smooth muscle cell derived
vs. leiomyoma (fibroid)
(lean muscle??)
10
Q
Transformation to Cancer…
A
Autonomy (loss of cell cycle control) Loss of contact inhibition Anchorage independent Immortal Anaplastic (without form) Pleomorphic (many forms) Undifferentiated (not mature)
