Module 8 Flashcards
What two diseases are highly associated with heart failure?
Hypertension
Diabetes
Incidences/Prevalence/Cost of Heart Failure
10 per 1000 over 65
Men > Women
POC > Caucasian
Diabetes > Other Comorbidities
875,000 patients yearly over 65
about 42,000 deaths, and contributes to 225,000 more
Cost: almost 18 billion yearly
In regard to heart failure we need to us ____ care
preventative
Number 1 Cause of Heart Failure (HF)?
Atherosclerosis
Atherosclerosis
fibrofatty plaque building up in the arteries causing the lumen to narrow
What basically occurs with heart failure?
The heart as a pump is impaired –> Left Ventricular problems –> Decreased contractility, lack of blood pumped for metabolic demands
What are the results of heart failure?
- Circulatory Congestion (Blood Backup)
2. Circulatory Overload (High blood volume)
What are HF intrinsic causes?
Causes of HF within / having to do with the heart itself
What are some intrinsic causes of HF?
- CAD
- AMI (Myocardial Infarction)
- Cardiomyopathy
- Myocarditis
- Congenital Heart Defects
- Aortic or Mitral Valve Disease
Ischemic Heart Disease (CAD)
Interrupted cardiovascular blood flow –> so ischemia and hypoxia occurs for the heart
Myocarditis
Viral or Bacteria Heart Muscle Inflammation
What are some secondary causes of HF?
COPD Pulmonary Embolism Hyperthyroidism A-V Fistulas HTN Excess Blood Volume Metabolic or Respiratory Acidosis Drug Toxicities Dysrhythmias
Pulmonary Embolism
Blood clot in the lungs leading to acute right sided heart failure (due to higher pressure force)
How does HTN lead to heart failure?
HTN –> Increased Afterload (pressure) –> Left Ventricle Hypertrophy –> Muscle is flabby and can pump less blood –> Dilated Enlarged Heart leads to inefficient pumping
A-V Fistula
Missing capillaries leads to bad nutrient exchange
can lead to heart failure
What causes excess blood volume before HF?
The RAA and ADH systems
How does metabolic or respiratory acidosis lead to HF
acidotic conditions lead to anaerobic metabolism and also lead to less contractility of the heart
Ventricular Fibrillation
Ventricle quivering from uncoordinated electrical signaling
Since its dysrhythmia, can lead to HF
What is the speed of HF pathogenesis?
Acute or Insidious
Heart Failure is associated with ___ ___
myocardial weakness
*This weakness can be due to comorbidities like nutrition, etc
During heart failure, _____ systems are actually making the heart weaker.
compensatory
In HF, decreased contractility leads to ..
decreased Cardiac Output with venous return being the same or increasing
How does the body react to decreased CO?
- SNS reflex activity –> Increased HR
- Renin Release –> Increased TPR and Blood Volume
- Anaerobic metabolism
- Increased O2 extraction by peripheral cells
What is the sympathetic response to heart failure?
HF = Decreased CO –> Decreased BP –> Activate SNS –> Increase in HR and Contraction Force w/ arteriole vasoconstriction
More work for a hurting heart!
What is the RAA system response to HF?
HF = Decreased CO –> Decreased Renal Perfusion/Kidney Flow Rate –> RAA System activate to release Renin –> Increased blood volume and TPR (increased preload and afterload)
What occurs to myocardial O2 needs in HF?
Increased HTN, HR, or Ventricular Enlargement occurs WITHOUT increasing consumption (since the cells grow but vessels do not)