Module 7: Part 1 Flashcards
most common cause of maternal mortality worldwide, accounting for 15% of maternal deaths
obstetrical hemorrhage
Most common cause for obstetrical admission to ICU and a risk factor for myocardial ischemia and infarction, and stroke
obstetrical hemorrhage
Majority of hemorrhage-related adverse outcomes are considered
preventable
Uterine contraction is stimulated by ____________ after delivery
endogenous oxytocin
primary mechanism for controlling blood loss at delivery
uterine contraction (endogenous oxytocin)
____________ creates a shearing forces that cleaves the placenta from the uterine wall
Uterine tetany
Uterine contraction constricts the ____________ (2) supplying the placental bed
spiral arteries and placental veins
After disruption of vascular integrity…
the coagulation cascade begins
homeostasis depends on…(3)
Vascular tissue
Platelets
Coagulation factors
initial homeostasis response (3)
Loss of vessel integrity
Platelets adhere to exposed collagen
Facilitated by von Willebrand factor (vWF)=primary hemostasis
primary factor of hemostasis
von Willebrand factor (vWF)=primary hemostasis
secondary hemostasis
- Unstable platelet plug
- initiation of coagulation cascade with deposits and stabilization of fibrin
which coag factor is ↓ in pregnancy
Protein S
which coag factors don’t demonstrate change in pregnancy
Protein C
Antithrombin III
EBL for vaginal vs cesarean delivery
EBL ≥ 500 ml for vaginal delivery
≥ 1000 ml for cesarean delivery
blood loss in OB is notoriously…
inaccurate, as bleeding is concealed within uterus, the drapes, retroperitoneal space
physiologic impact of blood loss depends on…
mother’s initial blood volume, hematocrit, and speed of blood loss
⭐️
late signs of blood loss
hypotension & tachycardia
____________ % may experience antepartum vaginal bleeding
25%
most cases of antepartum hemorrhage occur..when?
in 1st trimester
some causes of antepartum hemorrhage (2)
Cervicitis
Abnormalities in placentation (placenta previa or abruption)
greatest threat during antepartum hemorrhage is to…
the fetus
Placenta Previa is present when the placenta implants
in advance of the fetal presenting part.
placenta previa cause
is unclear but prior uterine trauma (scar) in common
low lying placenta previa
placenta near the os
placenta previa types (image)
____________ is an important anatomical part of the uterus
lower uterine segment (LUS)
the LUS has anatomical and functional aspects that can be
utilized to produce better outcomes in pregnancy and labor
Attachment of the placenta to the LUS leads to increased risk of
bleeding
Conditions associated with placental previa (6)
Conditions associated with placental previa
gold standard for diagnosis of placenta previa
transvaginal ultrasound (distance from the placental edge to the internal os can predict likelihood of antepartum hemorrhage and cesarean delivery)
CLASSIC SIGN of Placenta Previa is
painless vaginal bleeding during the second or third trimester