Module 7 Depressive disorders

Question 1

duration of symptoms required to meet criteria for MDD

Answer 1

2 weeks

Question 2

Difference between MDD and grief

Answer 2

MDD more persistently depressed impacts ability to feel joy
Grief comes in waves and focused on loss

Question 3

minimum duration of SSRI

Answer 3

6 months symptom free - then you can start to taper slowly if desired

Question 4

signs and symptoms of serotonin syndrome

Answer 4

Autonomic Instability: Increased temp, BP, pulse
Mental: confusion, agitation, hallucinations
GI: Nausea, vomiting diarrhea
Neuromuscular: tremors, loss of coordination

Question 5

Treatment for serotonin syndrome

Answer 5

STOP med, medical emergency, treat symptoms (decrease BP, benzos, cyproheptadine (serotonin antagonist)

Question 6

what is double depression

Answer 6

MDD on top of Persistent depressive disorder

Question 7

duration of symptoms for persistent depressive disorder

Answer 7

depressed mood for most of the day for more days than not for a two-year period

Question 8

Comprehensive plan for depressive disorders

Answer 8

lifestyle changes, TMS, ECT, therapy, meds

Question 9

SSRIs considered safe in older adults

Answer 9

sertraline, venlafaxine, citalopram, escitalopram, duloxetine, bupropion, mirtazapine

Question 10

why is prozac (fluoxetine) not recommended for older adults?

Answer 10

long half life and multiple CYP competing pathways

Question 11

why is paxil (paroxetine) not recommended for older adults

Answer 11

sedating and CYP 2E6 effect 0 multiple drug interactions