Module 7 Flashcards
cortical structures
frontal, temporal, parietal, and occipital lobes
subcortical structures
fornix, cingulate cortex, basal ganglia, and basal forebrain
brainstem,
which consists of the midbrain, pons, and the medulla
Serotonin
Brainstem: raphe nuclei
Helps regulate mood, arousal, and cognition
Norepinephrine
Brainstem: locus coeruleus
Regulates mood, arousal, attention, and cognition
Dopamine
Brainstem: substantia nigra
Regulates mood, arousal, cognition, and motor control
Acetylcholine
Basal forebrain: basal nucleus of Meynert
Regulate sleep, arousal, and attention
Low levels of serotonin, norepinephrine, and dopamine have been associated with
depressive symptoms.
Low concentrations of serotonin with high levels of norepinephrine have been associated with
anxiety symptoms
Too much dopamine with low concentrations of serotonin in certain areas of the brain lead to symptoms of
psychosis and mania
Dementia is notable for low concentration levels of
acetylcholine
common comorbid conditions that accompany excessive or uncontrollable anxiety
Hyperthyroidism, cardiopulmonary disorders, and traumatic brain injury (TBI) are
Major depressive disorder (MDD) is characterized by
at least 2 weeks of depressed/irritable mood, with at least four of the following: anhedonia, insomnia or hypersomnia, decreased self-esteem, low energy, poor concentration or indecision, changes in appetite, feeling slowed or restless, and thoughts of death or suicide
Persistent depressive disorder (PDD) is characterized by
depressive/irritable mood lasting for at least 2 years with at least two of the aforementioned depressive symptoms.
Symptoms of manic episodes include
euphoric/irritable mood, grandiosity, decreased need for sleep, talkativeness, racing thoughts, distractibility, increased goal-directed behavior or agitation, and an increase in reckless pleasure-seeking (having unprotected sex, spending excess money, foolish investments
Diseases that mimic depression symptoms
Parkinson disease, traumatic brain injury (TBI), recent myocardial infarction (MI) or stroke, and hypothyroidism may mimic depressive symptoms.
If the patient affirms one-sided hand tremor or difficulty starting movements, consider
Parkinson disease.
In a younger adult patient with unusual limb movements, you should assess the family history for
Huntington disease.
The mental status examination consists of six components:
appearance and behavior; speech and language; mood; thoughts and perceptions; insight and judgment; and cognitive function.
Lethargy
The lethargic patient appears drowsy but opens the eyes when spoken to in a loud voice and looks at you, responds to questions, and then falls asleep.
Obtundation
The obtunded patient opens the eyes when tactile stimulus is applied and looks at you but responds to you slowly and is somewhat confused.
Stupor
The stuporous patient arouses only after painful stimuli. Verbal responses are slow or even absent. The patient lapses into an unresponsive state when the stimulus ceases.
Coma
A comatose patient remains unarousable with eyes closed. There is no evident response to inner need or external stimuli.
Circumlocutions
, in which phrases or sentences are substituted for a word the person cannot think of, such as “what you write with” for “pen”
Paraphasias
, in which words are malformed (“I write with a den”), incorrect (“I write with a bar”), or invented (“I write with a dar”)
expressive, or Broca aphasia
, with preserved comprehension with slow, nonfluent speech
receptive, or Wernicke aphasia
, with impaired comprehension with fluent speech
Blocking
Sudden interruption of speech in midsentence or before the idea is completed, attributed to “losing the thought.” Blocking occurs in normal people.
Circumstantiality
The mildest thought disorder, consisting of speech with unnecessary detail, indirection, and delay in reaching the point. Some topics may have a meaningful connection. Many people without mental disorders have circumstantial speech.