Module 6: The Neonate Flashcards
(105 cards)
What 2 hormones plays an essential role in neonatal transition to extrauterine life?
- catecholamines
- cortisol
What role does hormone catecholamines (epinephrine, norepinephrine, and dopamine) play in neonatal transition?
- promote fluid clearance from lungs
Surge in response to the normal birth process:
- responsible for increased blood pressure after birth, - adaptation of energy metabolism,
- initiation of thermogenesis from brown fat
What 3 roles does hormone cortisol play in neonatal transition to extrauterine life?
- key regulatory hormone
- Clearance of lung fluid
- Lung maturation (anatomy and surfactant)
- Gut maturation
- cortisol level starts to increase around 30 weeks gestation
- Maturation of glucose metabolic pathways in the liver
- Maturation of the thyroid axis
The major adaptations associated with transition occur during the first 6-8 hours of life. What is the most critical adaptation required?
- establishment of effective respirations
What are the fetal physiological (cardiopulmonary) changes that occur during transition?
- initiation of gas exchange across alveolar membrane
- expansion of lungs with air
- rise in arterial pO2
- rapid decrease in pulmonary vascular resistance and increase in pulmonary blood flow
- pressure gradient changes (decreased right side pressure/increased left side pressure in heart)
- closure of circulatory shunts (foraman ovale, ductus arteriosus)
What is persistent pulmonary hypertension of newborn?
- During the stabilization period, which occurs over several hours, the pulmonary vessels remain very responsive to the effects of hypoxia.
- Hypo-expansion of the lungs, hypoxemia, –> persistent acidosis –> result in high pulmonary vascular resistance, delayed clearance of lung fluid, –> persistent right to left shunting
What are the initial steps of NRP (4)?
- dry
- warm
- stimulate the infant
- ensure there is an open airway
What 4 factors stimulate the newborn to take first breath?
- Chemical: factors in a newborn’s blood (low oxygen, high carbon dioxide, and low pH) which stimulate respiratory center in brain.
- Mechanical: release of pressure on a baby’s chest, as the chest is born, may stimulate breathing and chest expansion.
- Sensory: stimulation from drying, lights, sounds, smells all involved in stimulation of respiratory center
- Thermal: change from temperature from warm intrauterine environment to cool extrauterine environment stimulate skin receptors which stimulate respiratory center.
What are the major changes that take place in a newborns cardiopulmonary system during the transition to extrauterine life?
- the lungs become the primary organ of gas exchange (instead of the placenta); the lungs inflate, fluid is cleared from the alveoli, pulmonary vascular resistance decreases rapidly and there is increased pulmonary blood flow.
- The pressure gradient in the newborn’s heart shifts. Right sided pressure which was high in fetal circulation decreases, and left sided pressures which were low now increases. As a result the foramen ovale closes.
- Rising pO2 causes smooth muscle cells in the ductus arteriosus to constrict thereby closing the shunt.
- Removal of the low pressure placental system increases the pressure in a newborn’s circulation which increases circulation and pulmonary perfusion.
What is the role of lung surfactant?
- Surfactant lowers the surface tension of the alveoli thereby reducing the pressure required to keep the alveoli open.
- Decreased surface tension also results in increased lung compliance.
What is the rapid assessment of 5 parameters that is performed after completing the initial steps of NRP? When is it performed?
- Apgar score
- performed and scored at one and five minutes
What does APGAR score stand for?
- A: appearance (colour): generalized skin colour
- P: pulse (heart rate): based on observed movement of chest wall
- G: grimace (reflexes) “response to stimulation”: based on degree flexion and movement of extremities
- A: activity (muscle tone): based on presence of grimace, crying or active withdrawal
- R: respirations (breathing):
based on auscultation or palpation of umbilical cord
What does APGAR score (at one minute) of 7 or above mean? score of 4-6 mean? score of 3 or less?
- A score of 7 or above at one minute indicates that an infant is making a good adjustment to extrauterine life.
- A score of 4 to 6 at one minute indicates that an infant is having some difficulty
- A score of 3 or less at one minute indicates severe distress.
What APGAR score warrants another assessment at 10 minutes?
- Apgar of 7 or less at 5 minutes warrants another assessment of the five parameters at 10 minutes
What are the predictable phases of activity and rest during the transition period for full term healthy infant?
“What are the 3 stages of newborn transitions periods?”
- first period of reactivity: within minutes after birth and lasting for 30-60 minutes
- sleep: generally go into a deep sleep, lasting for 60-100 minutes
- second period of reactivity: between two to six hours after birth and can last from 10 minutes to several hours
What is the “first period of reactivity” during the transition period (first hours of life) include for infant?
- Within minutes after birth and lasting for 30-60 minutes.
- In this period, infants are in a quiet alert state: eyes wide open and capable of responding to their environment.
- Healthy infants are in an optimal state for the important first meeting with their parents. Heart rate increases to 160-180 bpm, then settles to 100-120 bpm by 30 minutes of age.
- Respirations may be irregular and fine crackles may be audible on auscultation of lung fields.
- Transitory grunting, nasal flaring, and chest retractions may be evident.
What is the “sleep period” during the transition period (first hours of life) include for infant?
- Following this initial period of reactivity, infants generally go into a deep sleep, lasting for 60-100 minutes.
- During this deep sleep, many physiologic needs stabilize: temperature regulation and adequate oxygenation and circulation.
- Respirations may be rapid but not laboured.
What is the “second period of reactivity” during the transition period (first hours of life) include for infant?
- this takes place approximately between two to six hours after birth and can last from 10 minutes to several hours.
- brief periods of tachycardia and tachypnea, increased muscle tone, and skin colour changes.
- meconium is usually passed in this period.
What 2 physiological adaptation tasks are included for neonate to be maintaining respirations?
- adjusting to circulatory changes
- regulating temperature
-other additional tasks of ingesting, retaining, and digesting nutrients, eliminating wastes, and regulating weight
What is the most effective ways of supporting physiologic transition for infants to extrauterine life?
- skin to skin contact with mother
- kangaroo care
- involves placing the naked infant onto the naked chest of the woman
What are 4 benefits of neonatal skin to skin care?
- stabilizing respirations and oxygen saturation
- thermal regulation
- reduces stress and crying (lower salivary cortisol levels)
- increased incidence and duration of breastfeeding
- improves infant state organization and self-regulation
- reduces apnea and bradycardia
- facilitates neurodevelopment
- accelerated weight gain
- decreases pain response to painful procedures
What are 4 maternal benefits of skin to skin care?
- Increased self-confidence, competence, and self esteem
- Enhanced parent-infant attachment
- Increased incidence and duration of breastfeeding
- Positively affects maternal mood/behaviour
- increased milk supply
- Increased confidence in meeting infant’s needs
What behavioural tasks must a neonate accomplish to adapt to extrauterine life?
- establish regulated behavioural tempo independent of mother
- processing, snoring, organizing multiple stimuli
- establishing relationship with care givers and environment
- regulating physiologic functioning,
- motor organization,
- responding to stimuli and
- regulating states, and interacting with the environment
What are the 4 level of adaptations that Brazelton & Nugent (2011) describe infants progress as they adapt to their environment?
- First level: regulate their physiologic functions: heart rate, respiration, and temperature.
- Second level: motor organization; reduce excessive activity and improve muscle tone
- Third level: state regulation, predictable sleep/wake states and able to react to stress
- Fourth level: social interaction, able to attend to visual and auditory stimuli