Module 6 Flashcards
Distinguish between an isometric and isotonic contraction.
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Draw the length versus force diagram for muscle and label the three lines that
represent passive (resting), active, and total force. Describe the molecular origin of
these forces in the three muscle types.
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Explain the interaction of the length-force and the force-velocity relationships and
how they vary in the three muscle types
.
List the energy sources of muscle contraction and rank the sources with respect to
their relative speed and capacity to supply ATP for contraction and how they are
different in the three muscle types.
.
Distinguish between an endplate potential and an action potential in skeletal
muscle.
.
List the possible sites for blocking neuromuscular transmission in skeletal muscle
and provide an example of an agent that could cause blockage at each site.
.
Distinguish between a twitch and tetanus in skeletal muscle and explain why a
twitch is smaller in amplitude than tetanus and the continuum of force
development between a twitch and tetanus including the intracellular events.
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Describe the differences in actomyosin regulation of, respectively, smooth and
skeletal muscle and indicate the structural similarities in their respective contractile
units.
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Explain why smooth muscles can develop and maintain force with a much lower
rate of ATP hydrolysis than skeletal muscle.
.
Describe the distinguishing characteristics of multi-unit and unitary smooth
muscles.
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Describe the mechanisms responsible for myofilament calcium sensitization and
desensitization.
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Construct a table of structural, enzymatic, and functional features of the three
major categories (fast-glycolytic, fast-oxidative-glycolytic, and slow-oxidative fiber
types) of skeletal muscle fiber types and their relative plasticity
.
