Module 5 - Protein Flashcards
What is Protein
- Component of every living cell
- all proteins are made up of amino acids
- every AA contains Nitrogen
Peptide bonds
Covalent bond that links AA together to form a protein
Dipeptide
2 amino acids coming together
Water is released
Tripeptide
Bonds have 2 peptide bonds
Primary structure
Linear order of AA
Secondary Structure
Local spatial arrangement of polypeptide backbone.
Tertiary Structure
Final 3D shape of protein.
What happens to protein when it undergoes ‘denaturation’
Protein denature means (destroying 3D shape) but doesnt break any peptide bonds.
example/ protein hitting stomach acid.
Red Blood Cell Vs Sickle Cell anemia
PolyPeptide
Normal: Normal
Sickle: Altered
Hemoglobin Shape
Normal: Normal
Sickle: Altered
Hemoglobin Arrangement
Normal: Individual Molecules
Sickle: Long chains of Molecules
Red Blood Cell shape
Normal: Disc
Sickle: Sickle
Sickle Cell
Happens when there is reduced oxygen carrying capacity
Proteins that regulate “body processes”
Some Hormones
- Insulin, Glucagon
Enzymes
- Lipase, Amylase, Trypsin
Neurotransmitters
- Serotonin
Proteins that help Transportation substances throughout
Hemoglobin - Transports oxygen
Transferrin - Blood transport proteins for iron.
Proteins that work as apart of immune defence
Antibodies - proteins with sugar groups attached to them
Proteins that growth and repair tissues
Muscle Protein:
a) Actin/Myosin
b) Collagen
Normal turnover (breakdown + Replacement)
How does Stomach help in protein digestion
- HCL Denatures proteins
- Protein begins digestion in stomach –> PEPSIN enzyme lives in stomach to break down peptide bonds.