Module 5 Cancer drugs Flashcards
1
Q
Alkylating Agents
A
Cyclophosphamide
Cisplatin
2
Q
Antimetabolites
A
5- FU
Methotrexate
Gemcitabine
6-MP
3
Q
Natural Products
A
Etoposide
Paclitaxel
Vincristine
4
Q
Antitumor Antibiotics
A
Bleomycin
Doxorubicin
Mitomycin
5
Q
Hormonal
A
Prednisone
Tamoxifen
6
Q
Nitrogen Mustards
A
- Alkylating agents
Mechlorethamine
Cyclophosphamide
Ifosfamide
Melphalan (L-sarcolysin)
Chlorambucil
7
Q
Imatinib (Gleevec)
A
- bcr-abl tyrosine kinase
- Administration to patients with chronic myeloid leukemia results in decreased proliferation and survival of leukemia cells
- Tyrosine kinase inhibitors block the action of enzymes called tyrosine kinases. Tyrosine kinases are a part of many cell functions, including cell signaling, growth, and division.
8
Q
Prodrugs
A
6MP
TAMOXIFEN
CYCLOPHOSPHAMIDE
IRINOTECAN
TEMOZOLAMIDE
XELODA
9
Q
CCS
A
Bleomycin
vincristine
paclitaxel
6MP, 5FU, Methotrexate
Xeloda (Capeticabine)
Irinotecan
10
Q
Renal Clearance Chemo Drug
A
Bleomycin
Capecitabine
Cisplatin, all platinum containing complexes
Cyclophosphamide
Methotrexate
Mitomycin
Carmustine
Aminoglycosides
