Module 5 Flashcards

1
Q

Significance of proteins

A

Muscle Contraction
Enzymes
Some hormones
Connective tissue and muscle

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2
Q

All enzymes are…

A

Proteins

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3
Q

Hormones to know…

A

Insulin
Growth hormone
Glucagon
Epinephrin, norepinephrine- derived from a single amino acid

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4
Q

How many different amino acids?

A

20 diffrent amino acids- 20^x for different combos

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5
Q

Primary Structure

A

Amino acid sequence

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6
Q

Secondary structure

A

Arrangement of amino acids in “space”

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7
Q

Tertiary structure

A

The 3-D shape- caused by folding, coiling, sheeting, etc

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8
Q

Quaternary structure

A

Protein subunits combined to form 1 protein

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9
Q

How are amino acids classified?

A

Structure of the side chain

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10
Q

Classifications of amino acids?

A
Acids
Bases
Thiols
Hydroxyls
Alkanes
Phenyls
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11
Q

What is the simplest amino acid structure?

A

Glycine

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12
Q

What are non-polar amino acids-?

A

Side chains that lack electrical charge- 4 have alkane side chains [Ala, Val, Leu, Ile]

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13
Q

What are the names of non-polar amino acids?

A
Alanine
Valine
Leucine
Isoleucine
Proline
Tryptophan
Phenylalanine
Methionine :)
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14
Q

What are polar amino acids-? - Referring to Polar Neutral ones

A

They have polar side chains- BUT: at pH 7 they are neutral-!

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15
Q

What are the names of polar amino acids when pH is neutral at 7-? They are also known as Polar Neutral

A

Serine
Threonine
Tyrosine
Cystine

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16
Q

What are acidic amino acids-?

A

They have polar acid side chains- BUT are ionized [negatively charged] at pH 7-!

17
Q

What are names of acidic amino acids-?

A

Glutamic acid

Aspartic acid

18
Q

What are amino acids with amine side chains?

A

They have an amino group attached to the carboxyl-carbon [replacing the -OH on the carboxylic acid]

19
Q

What are the names of the amino acids with amine side chains?

A

Glutamine

Asparagine

20
Q

What are basic polar amino acids-? Referring to when they become + at a certain pH

A

Polar, yet positively charged when pH is 7

21
Q

What are the names of basic polar amino acids-?

A

Histidine
Lysine
Arginine

22
Q

What does the order or “sequence” of an amino acid determine-?

A

How amino acids will interact with each other- these interactions will influence how the long chains of amino acids bend and fold as the protein develops - the final 3-D shape is determined by the sequence of the amino acids

23
Q

What are some bioactive proteins?

A

Enzymes- only catalyze certain reactions and specific uses
Hormones
Hemoglobin
Myoglobin
Contraction proteins like myosin and actin

24
Q

What are essential and nonessential amino acids?

A

Essential: needed in the diet- also called indispensable

Nonessential: body can synthesize it- called dispensable

25
Q

How is the genetic code read and converted into the sequence of amino acids in a protein?

A

Messenger RNA is decoded by ribosome outside the nucleus to make a specific amino acid - when an entire nucleic acid message is translated, a protein is formed-!