Module 4 study guide Flashcards
Erythrocytes
Responsible for tissue oxygenation
lymphocytes
White blood cells
platelets
Made of bone marrow that form clots and stop or prevent bleeding
Erythropoietin
Hormone excreted by kidney in response to decrease oxygen (hypoxemia) in blood
hematopoiesis
RBC production
erythroblasts
Red bone marrow that synthesize HbG and is an intermediate in the initial stage of RBC formation
reticulocytes
Young and new RBC’s form bone marrow not mature enough to carry 02
Normal RBC level
male: 4.7-6.1 per mm3
female: 4.2-5.4 per mm3
Normal HbB level
iron and oxygen transport protien
Male: 14-18 g/dL
Female: 12-16 g/dL
Normal Hct level
Male: 42-52%
Female: 37-47%
MCV
Mean Corpuscular Volume (size)
Normal 80-100
Buerger Disease
Males
Vasospasm of arterial vessels chronic ishema
DVT
Venous Thrombosis
Clot formation in deep larger veins of the leg
Virchow’s Triad
Unstable angina
Symptoms at rest
Dyspnea
Diaphoresis
Hyperchromic
MCHC > 36
Microcytic
Iron deficiency Anemia
MCV <80
Macrocytic
Vitamin b12 deficiency
MCV <100
MCHC
Hemoglobin concentration/color amount of Hbg in a volume of RBC’s normal 32-36
Hypochromic
Folate deficiency
MCHC < 32
Prinzmetal’s angina
Chest pain
vasospasms
occurs at rest
Myocardial Infaraction
Injury
unless ischemia is relieved… death of myocardial tissues
CAD
Chronic clinical manifestations related to ischemia
Coronary Artery Disease
Virchow’s Triad
Venous Stasis- blood flow reduce
Endothelial Injury
Hypercoagulability-clot formation-DVT- polycythemia
Aneurysm
Weakness in vessels walls
Tunica intima
Tunica media
Adventitia
Acute Coronary Syndrome (ACS)
Unstable angina
HDL
High density
>60
remove fats & cholesterol in blood and cells
LDL
Low density
<100
Atherosclerosis
General term for hardening/stiffening of vessel walls
Cholesterol
<200
Stage 2 HTN
> 160->100
Stage 1 HTN
140-159/90-99
Prehypertension
120-139/80-89
Normal BP
<120/<80
Stable angina
Reversible
transient
pallor
relieved by rest
HTN
Constant elevation of arterial BP sustained increase in peripheral arterial resistance and or increase in circulating volume
Preload
Amount of stretch in the left verticle at the end of diastole
DIC
Acquired disorder in which clotting and hemorrhage simultaneously occur
Von Willebrand Disease
Hemophila blood fails to clot, leads to poor platelet adhesion
Raynaunds diesease
Female
Hyperactive SNS- vasospasm of small arteries
Hemophila A
X-linked recessive disease
Factor 8
ITP
Immune response
Chronic in adults- acute in children
Spleen
Hemophilia
Genetic condition
Thrombocytopenia
Platelet count < 150,000mm3
<50,00- minor trauma
<15,000-spontaneous bleeding
<10,000- severe bleeding
Polycythemia
Increased risk of clotting due to increase numbers of RBC’s
Sickle Cell Disease
Genetic Disorder
Red cell deform- dehydration, stress, move slow, less elasticity + blood viscosity hemolysis in spleen
Myocardial Ischemia
Reverisble imbalance between supply and demand
occurs within 10 seconds
Anemia
Reduction in total number of erythrocytes in circulating blood quality/quantity Hbg
Reduced oxygen carrying capacity
Triglycerides
<150
Transfer Fat and glucose from liver
