Module 4 - Addictions Flashcards
What constitutes a ‘binge’ (alcohol)
5 standard drinks for males, 4 for females in 2 hour period. OR blood alcohol of 0.08%
What is the latin word for addiction?
‘Addicere’ - to give or bind a person to one thing or another
What is the Psychiatric View of Addiction?
Drug addiction has aspects of both:
- Impulse control disorders
- compulsive disorders
Drug addiction progresses from impulsivity to compulsivity in a collapsed cycle of addiction that consists of three stages: preoccupation/anticipation, binge/intoxication, and withdrawal/negative affect
What is the Psychodynamic view of addiction? What is the core element?
- focus on the factors that produce vulnerability to addiction.
- Two critical elements (disordered emotions and disordered self-care) and two contributory elements (disordered self-esteem and disordered relationships)
- the core element of this psychodynamic perspective is a dysregulated emotional system in individuals who are vulnerable to addiction.
What is the core element of the Psychodynamic view of addiction?
a dysregulated emotional system in individuals who are vulnerable to addiction
What are Social Psychological and Self-Regulation Views of Addiction ?
- Underregulation, reflected by strength deficits, a failure to establish standards, conflicting standards, attentional failures, and misregulation (misdirected attempts to self-regulate) can contribute to the development of addiction- like behavioral patterns
- can be facilitated by lapse-activated causal patterns
- Executive function deficits, self-regulation problems, and frontal lobe dysfunction or pathology constitute risk factors for biobehavioral disorders, including drug abuse.
- Deficits in frontal cortex regulation in children or young adolescents predict later drug and alcohol consumption,
What is Brown’s (1993) criteria for addiction?
(SET WCR) o 1. Salience o 2. Euphoria o 3. Tolerance o 4. Withdrawal o 5. Conflict o 6. Relapse and reinstatement
what is the lifetime prevalence of substance dependence among people who began using drugs under the age of 14
34%
What % of genetic factors account for total variability?
40%
What are the Involved brain structures in addiction?
o Nucleus accumbens (learning)
o Limbic structures (learning/conditioning)
o Orbitofrontal cortex (motivation/drive)
o Anterior cingulate gyrus (inhibitory control)
o Prefrontal cortex (inhibited in gambling)
What brain chemistry is involved in addiction?
- Dopamine (reward and motivation)
- Orbito Frontal and Anterior cingulate (interconnected for sensory modslities)
- Alcohol: GABA-A, NMDA, serotonin
What is the role of the hypothalamus in addiction?
critical for motivated behaviour (eating, drinking, sex).
Primarily consummatory behaviours (not goal directed).
Activation of the HPA xis during times of stress can trigger need for reward.
What is the mesolimbic pathway?
- Ventral Tegmental Area (VTA)
- Median Forebrain bundle (MFB)
- Nucleus Accumbens (NAcc)
- Limbic System
Starts at VTA -> prefrontal -> cingulate -> Perirhinal cortex
Neurocognitive Processes Underpinning Addiction:
- Attentional Bias (hyperattentive)
- Reward Processing
- Error Processing (insensitivity to future negative consequences)
Explain the bottom up and top-down system:
The bottom-up system, reflecting the impulse or reactive system, encourages rewarding, habitual behaviours and prioritises responding to available cues above consideration of long term consequences.
In contrast, the top-down system, reflects executive or reflective functions, including self-control, planning, memory and resistance to temptation
- In healthy individuals top down processing over runs bottom down but in an addict it’s the other way
what do Stevens and colleagues (2014) argue is the core pathological feature of substance use disorders?
impulsivity