Module 4 Flashcards
Aims of GBD Project
- Use systematic approach to to summarise the burden of disease and injury at the population level based on epidemiological principles and best available evidence
- To take account of deaths as well as non-fatal outcomes (disabilities) when estimating the burden of disease.
Reasons for GBD Project
- To get more information on non-fatal outcomes of disease (disability)
- Difficult to estimate comparative burdens of different conditions
Disability Adjusted Life Year (DALY)
= Years of Life Lost (YLL) + Years Lived with Disability (YLD)
Years of Life Lost to mortality (YLL)
- Number of deaths
- Years lost per death (ideal age)
Years Lived with Disability (YLD)
- Number of cases with non-fatal outcomes
- Average duration of non-fatal outcomes
- Disability weight (representing severity of impairment)
Demographic Transition
Decline in fertility and mortality rates observed in most developed and several developing countries.
Epidemiological Transition
A characteristic shift in the composition of causes of death and disability from communicable to non-communicable diseases
Risk Transition
Changes in the risk factor profiles as countries shift from low to higher income countries, where common risks for perinatal and communicable diseases (e.g. unclean water) are replaced by risks for non-communicable diseases (e.g. tobacco)
Double burden of disease
In many middle-income countries, previously common risks for perinatal and communicable diseases co-exist with increasing risks of non-communicable diseases.
DALY/GBD Approach to measuring disability
- No disability weighting in regards to social positions, where they live, access to healthcare
- Represents people with a disability as a burden
- Deficit approach, all blame is on the disabled
- Medical Mode of Disability
Medical Mode of Disability
- Disabled people are defined by their condition
- Regards disability as an individual problem and promotes the view that they are dependants
- Exclude disabled from society
- Control resides with professionals
Social Model of Disability
- Disability is a social issue caused by policies, practices, attitudes, and environment
- Disabling factor is inaccessible environment
- Focused of ridding society of barriers
- Right to heath approach
Right to Health
- Aim to promote, protect and ensure equal human rights and freedoms for all
1. Respect (no discrimination)
2. Protect (no interference by 3rd parties)
3. Fulfil (adopt measures to achieve equality) - Freedoms from and entitlements to
Recommendations of Commission on the Social Determinants of Health
- Improve daily living conditions
- Tackle the inequitable distribution of power, money and resources
- Measure and understand the problem and assess the impact of action
Global HIV Trends
- 2/3 of the people in the world infected with HIV live in Sub-Saharan Africa
- 60% of those infected with HIV in Sub-Saharan Africa are female
- The proportion of people in the world infected with HIV is increasing while the death rates due to AIDS and the new people becoming infected with HIV is going down
- 95% of new infections of HIV were in low and middle income countries.
Pacific Island Trends
- 90% of the HIV burden its in Papua New Guinea
- Largely heterosexual transmission
- Other PI nations have a low prevalence of HIV/AIDS but high prevalence of other STI’s makes HIV i potentially major problem
New Zealand Trends
- 75% of people living with HIV in NZ are men who got HIV from a man
- 15% is from heterosexual transmission
- No mother to child cases since 2007
Global Factors Shaping Epidemic
- AIDS related deaths are decreasing and people are living with HIV longer due to better treatment and care
- High proportion of people living with HIV do not know their HIV status
Main modes of HIV transmission
- Unprotected sex with HIV+ person
- Sharing unsterilised injecting equipment (NZ Needle Exchange Programme)
- Mother to child transmission
- Blood bourn
Feminisation of HIV Epidemic
Increasing proportions of new infections are among women, primarily due to heterosexual transmission of the infection.
- Of the new infections among people aged 15 years and older:
- 47% were among women, at a global level heterosexual transmission has become the dominant mode of transmission.
- 39% Of new infections are among people ages 15-24 years (majority are female and live in Sub-Saharan Africa)
Prevention Impact of Antenatal Screening
- Without treatment 1/3 children born to HIV+ mothers will become infected
- Can screen and treat with anti-retroviral drugs to prevent
- Sub-Saharan Africa is home to 91% of pregnant mothers needing Rx
Main opportunities for Intervention
- Safer sex
- Safer products
- Reduce discrimination
- Increased access to healthcare
Distribution of RTI’s
- 1.2 million people a year die of RTI’s
- 20-50 million more are injured/disabled
- More than 95% of the burden of RTI is from low and middle income countries
- 1-2% of GDP is provided to low income countries - exceeds international aid
Trends of RTI’s
- Percentage change in RTI fatality is going down for rich countries and up for poor countries - socioeconomic differentials
- Males have a much greater fatality rate due to RT’sI than women - mostly ages 15-45