Module 3 Video Flashcards
Pharmacology (definition)
how drugs interact with the body- side effects, contraindications, effectiveness
Pharmacokinetics (definition)
how drugs move through the body- ADME
Pharmaceutics (definition)
how drugs are created- tablet, capsule, suppository
What does ADME stand for?
Absorption, Distribution, Metabolism, Excretion
What does Absorption refer to? (ADME)
The process by which drugs are absorbed into the bloodstream in order for them to produce an effect, especially in the GI tract
What does Distribution refer to? (ADME)
the process by which drugs are taken to their site of action
Distribution primarily takes place in the ____
bloodstream
3 factors that may affect distribution:
Drug’s solubility, size and protein binding
What does the M in ADME stand for?
Metabolism
What does Metabolism refer to? (ADME)
the process by which drugs are changed by enzymes in order to become active, inactive, or for elimination
What are enzymes?
Complex proteins that speed up or slow down chemical reactions
Metabolism is primarily done by the ____
liver
What is a Metabolite?
the substance resulting from the body’s transformation of an administered drug
What does Excretion refer to? (ADME)
The process by which drugs are removed from the body
How can drugs be removed from the body? (naturally)
Renally in urine, or in stool