Common Drug Interactions & Contraindications (Mod 2 Doc)

Question 1

Warfarin (drug interactions)

Answer 1

NSAIDs, Antibiotics, Fish Oil, Coenzyme 10, Garlic Supplements, Ginko Biloba, Vitamin K

Question 2

Warfarin (side effects)

Answer 2

Excessive bruising/ bleeding

Question 3

Warfarin (pregnancy category)

Answer 3

Yes, X

Question 4

NSAIDS (drug interactions)

Answer 4

When taken with Lithium or Methotrexate, can cause toxicity

Increased risk of bleeding with Coumadin (warfarin)

Question 5

NSAIDs (pregnancy category)

Answer 5

No

Question 6

HMG- CoA Reductase Inhibitors (-statins) (food interaction)

Answer 6

Grapefruit inhibits metabolism leading to muscle damage

Question 7

HMG-CoA Reductase Inhibitor (-statin) (Pregnancy category)

Answer 7

Yes, X

Question 8

Benzodiazepines & Hydrocodone (drug interactions)

Answer 8

When taken together, benzodiazepines and hydrocodone can cause respiratory depression

Question 9

Benzodiazepine (pregnancy category)

Answer 9

Yes, D

Question 10

Clopidogrel & PPIs (drug interaction)

Answer 10

When taken together, Clopidogrel and PPIs can reduce effectiveness of Clopidogrel

Question 11

Antibiotics (drug interaction)

Answer 11

Increased risk of bleeding with anticoagulants, reduce effectiveness of birth control

Question 12

Antibiotics (pregnancy category)

Answer 12

Varies, Doxycycline is Category D

Question 13

Ace Inhibitor (ACEi) (pregnancy category)

Answer 13

Yes, D

Question 14

Serotonin Syndrome (drug

Answer 14

SSRIs, or SNRIs and MAOIs taken together can cause serotonin syndrome

Question 15

Digoxin & Diuretics (drug interaction)

Answer 15

When taken together, Digoxin and Diuretics can cause increased risk of Digoxin toxicity

Question 16

Lithium (drug interactions)

Answer 16

Alcohol, NSAIDs, and Methotrexate should be avoided when taking Lithium

Question 17

Lithium (pregnancy category)

Answer 17

Yes, D