Module 3 Unit C Practice Quiz Flashcards

1
Q

A person is experiencing first trimester bleeding and is 9 weeks’ gestation by certain dates.

What non-serious/less serious cause of first trimester bleeding is most likely, given the timing of the bleeding?

A

Subchorionic hemorrhage

[Timing of initial bleeding is typically between 8-10 weeks gestation.]

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2
Q

A patient presents for a first OB visit and mentions that they have a brother with Down Syndrome. What is the most appropriate next step to take as a result of this finding?

A

Further explore the patient’s thoughts about their brother’s condition related to their own pregnancy

[Although both B and C are reasonable recommendations. The first and most appropriate step at this time is to explore the patient’s thought’s about their brother’s condition related to their own pregnancy. Remember, patient preferences and values often steer the direction of these sensitive discussions.]

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3
Q

A woman presents for prenatal care at 6 weeks gestation. While taking her family history, the woman mentions that she has a brother who has developmental delays and she does not know the cause. Which of the following would be most important to include in the care plan for this woman at this visit?

A

referring her to a genetic counselor

[The most important thing to include in the care plan for this woman at this visit is a referral to genetic counseling. Here a genetic counselor could dive deeper into her family history and provide their recommendations regarding genetic testing and or carrier screening. From there it could be determined if this patient wants to consider genetic screening, including the nuchal (between 10-13 wks) and blood work (sequential, Cf DNA, Etc.), and at a later date, the anatomy scan (between 18-20 wks).]

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4
Q

Which of the following is the preferred statement to use when explaining the risk of Down Syndrome? (For purposes of this question, assume that the patient has a 1:100 risk of Down Syndrome).

a) “The relative risk that your baby will have Down Syndrome is lower than the risk of it having a Neural Tube Defect.”
b) “The chance that your baby will have Down Syndrome is less than 2 percent.”
c) “The chance that your baby will have Down Syndrome is 1 in 100, and there is a 99% likelihood that your baby will be normal.”
d) “The chance that your baby will have Down Syndrome is 1 in 100, and there is a 99 in 100 likelihood that your baby will not have Down Syndrome.”

A

d) “The chance that your baby will have Down Syndrome is 1 in 100, and there is a 99 in 100 likelihood that your baby will not have Down Syndrome.”

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5
Q

The sensitivity of a test is the:

A

True positive rate

[The sensitivity of a test is its ability to correctly identify the people who have the condition. In other words, the true positives.]

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6
Q

A patient requests an ultrasound “to be sure everything is okay with the baby.” How should the clinician respond, keeping shared decision-making and sound practice in mind?

A

Ask the patient about her concerns and discuss the factors pertinent to making a decision about ultrasounds.

[It is best to first explore the patient’s concerns and preferences before proceeding to establish a plan of care.]

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7
Q

Assuming no prior lab results are available, which of the following lab tests are most appropriate when the CNM/WHNP suspects a missed abortion?

A

Blood type/Rh factor

[If you are suspicious of a MAB, you would not need a UPT as that will likely remain positive for a while and would have very little clinical value. You would however, want to know if the patient was Rh negative, in which case, you would likely give Rhogam (unless it was documented that the FOB was also Rh negative).

Coagulation studies and liver enzymes are “zebras” and would not typically be performed when suspicious of a MAB.]

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8
Q

Offering informed consent when discussing genetic screening options is an example of which ethical principle?

A

autonomy

[A patient cannot be autonomist, if they do not have accurate and appropriate information from which to make a fully informed decision.]

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9
Q

A 22-year-old G1P0 at 8 weeks gestation presents to clinic with a report of cramping and bright red spotting for the last 2 days. The patient is tearful that something may be wrong. Of the following, the most appropriate action would be to:

A

Perform speculum and bimanual exams

[A speculum exam would allow you to determine if her cervix is dilated, vaginal bleeding, and if there is potential vaginitis which may also be a source of spotting during pregnancy. A bimanual exam would help you assess if her uterus is appropriately sized for gestational age. Now, in some institutions, a patient is automatically scheduled for a TVUS before being added to your schedule when there is a c/o 1st trimester vaginal bleeding. The take away here is that you would first need to collect more information!]

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10
Q

A 22-year-old G3P1011 at 7 weeks gestation by LMP presents to clinic reporting an episode of spotting yesterday the size of a 50-cent piece. She reports occasional headache and fatigue. Her uterus is enlarged on pelvic exam. The MOST important data to gather at this visit is:

A

Presence of pain

[The key here is the most important piece of information to gather. Early pregnancy dated by LMP, w/ spotting, you always want to take into consideration the possibility of an ectopic. The presence of pain, most suspiciously unilateral pain, would raise your concern for an ectopic pregnancy.]

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11
Q

A patient presents at 9 weeks gestation with a report of persistent bright red bleeding for 2 days, similar to a heavy period. The patient had their first visit one week ago and had no concerns. Today, other than the bleeding, the patient feels well. The next most important step in the clinician’s care is to:

A

Obtain an ultrasound to assess fetal cardiac activity and other indicators the health of the pregnancy.

[Given that this patient has had persistent bleeding (like a heavy period), the first thing you would want to do is establish viability. Given her gestational age, the best way to determine viability is via US.

Although Chlamydia and gonorrhea can cause vaginal bleeding, it is not typically heavy bleeding, and may be something you’ve considered evaluating for, AFTER obtaining an US.

You would want to complete your assessment of the patient prior to proceeding with consultation.

A CBC would typically be considered after first obtaining an US. Coag studies are not routinely drawn and certainly would not be the MOST important data to collect.]

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12
Q

What is most appropriate to offer a person at 13 weeks gestation who has a positive first trimester screening test (NT and serum screen)?

A

referral to a genetic counselor

[Although all of these options may be appropriate at some point, the most appropriate thing to do is to refer to a genetic counselor or perinatologist (depending on the facility resources). The perinatologist would counsel the patient on all of their options and will often be the one to perform any higher level ultrasounds, diagnostic testing (if elected), and loop back with the referring provider to discuss if the patient has elected for a termination.]

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13
Q

A patient is excited to present to prenatal care because she had a positive pregnancy test at home 3 days ago. A urine pregnancy test in the office is also positive. The patient feels great today without any cramping, pain, or bleeding.

The patient thinks her last period might have started about 4-5 weeks ago but she can’t remember whether it was a normal period or if it started when she expected it to start. Upon further discussion, she says that perhaps she’s wrong about the date? Her periods are fairly irregular.

The clinician and patient agree that an ultrasound is the best way to date the pregnancy so the patient undergoes a vaginal ultrasound in the office. The ultrasound results are unclear with a gestational sac visible but no embryonic pole or cardiac activity can be identified.

How should the clinician proceed?

A

Offer the patient a repeat ultrasound in one week with specific precautions to call immediately if she experiences any bleeding or pain.

[This patient is possibly 5 weeks.

This patient is also possibly further along with a MAB.

Until cardiac activity is seen, we cannot confirm viability.

Returning in 1 week we should also be able to see a yolk sack, embryonic pole, and possibly cardiac activity. ]

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14
Q

A patient is in clinic for a first prenatal visit at 12 weeks by sure, normal LMP and regular cycles. The clinician finds the uterine fundus at the level of the symphysis. The clinician uses a Doppler but is unable to hear fetal heart tones. What should the clinician conclude about whether this is an expected finding?

A

FHTs should be audible by Doppler in this patient so further evaluation is warranted.

[By 12 weeks EGA, you should be able to obtain FHTs via doppler, therefore, further evaluation is warranted. Now…adipose and uterine position can make it more or less difficult to hear fetal heart tones. If an unsuccessful attempt is made to hear fetal heart tones, the pregnant person should be given an opportunity to return in a week or so to try again]

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15
Q

What is the typical human chorionic gonadotropin (hCG) pattern for a hydatidiform molar pregnancy?

A

Abnormally high levels of hCG

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16
Q

When is chorionic villus sampling (CVS) typically performed?

A

10-14 weeks

[CVS is performed between 10-14 weeks. The easiest way to remember this is to recall that 1st trimester genetic screening is also performed between this timeframe.]

17
Q

Which of these tests is diagnostic, rather than screening?

a) Nuchal translucency (NT)
b) Chorionic villus sampling (CVS)
c) Cell-free DNA (cfDNA)

A

b) Chorionic villus sampling (CVS)

NT/serum screen:
-Noninvasive; does not risk fetal harm
-Positive results (abnormally thick nuchal fold or abnormal serum markers) require confirmatory testing
-In some settings, after the NT/serum screen, patients can choose to proceed to diagnostic testing OR have additional serum markers drawn in the second trimester OR do no additional testing

Chorionic villus sampling:
-Results available in less than one week
-Invasive; risks of pregnancy loss, harm to fetus, infection, and amniotic fluid leakage. Specific stats for these risks vary with the provider performing the procedure
-As a diagnostic test, it can be tremendously reassuring when the results are negative/normal

Cell-free DNA/NIPT/NIPS:
-Noninvasive; does not risk fetal harm
-Positive results require confirmatory testing
-Very high negative predictive value (a negative test is quite reassuring that the fetus does NOT have an aneuploidy)
-Higher positive predictive value (a positive test is likely to be a true positive) compared with traditional genetic screening tests

18
Q

Which of the following conditions does cell-free DNA screen for? [select all that apply]

a) Trisomy 21
b) Trisomy 13
c) Spina bifida
d) Trisomy 18
e) Cystic fibrosis

A

a, b, & d Trisomy 21, 13, & 18

[cfDNA screens for trisomy 13, 18, and 21.

CF- would be assessed via carrier screening.

Spina bifida would be screened via the AFP blood draw during the 2nd trimester), as well as US.

19
Q

True or False? A patient is 8 weeks’ gestation by sure, normal LMP and regular cycles. They may have a first trimester screen (nuchal translucency ultrasound and maternal serum markers) TODAY.

A

False

[This is false. Recall that the 1st trimester screening (maternal serum markers, and NT scan) are performed between 10-14 weeks.]

20
Q

A patient with early pregnancy bleeding is 5 weeks by certain LMP. The serum beta hCG levels are as follows: Mon. 6/14: 750, Wed. 6/16: 1,100, Fri. 6/18: 1,320. Which of these serious causes of first trimester bleeding is most likely?

a) Molar pregnancy
b) Ectopic pregnancy

A

Ectopic pregnancy

[Recall that with a suspected ectopic pregnancy, the beta hCG often does not double as expected every 48 hrs. In a molar pregnancy the beta hCG is often much higher than expected.

A normal hCG progression would be: Mon. 6/14: 750 Wed. 6/16: ~1,500 Fri. 6/18: ~3,000]

21
Q

A patient is interested in having chorionic villus sampling (CVS) and wants to know specific statistics associated with risk of miscarriage from the procedure. How should the CNM/WHNP respond?

A

“I’d like my physician colleague who will be performing the procedure to share their statistics with you. That is an important part of what the physician will talk to you about during your counseling appointment.”

[Although it is okay to provide general information regarding a CVS, It is most appropriate to have the physician who will be performing the CVS meet with the patient first to discuss the risks, benefits, and specific statistics associated with the procedure.]

21
Q

Defining the moral goodness of an action by its consequences best describes the concept of:

A

Beneficence

[Beneficence- to act in the benefit of the patient (without regardless of the consequence).

non-maleficence-to avoid harm to the patient (regardless of the consequence).

utilitarianism- differs from the two in that the ends justify the means. For example, mandating the covid-19 vaccine for hospital staff is meant to reduce spreading covid-19 to compromised patients. This consequence does not take into consideration the inconvenience and potential small risk of harm to the staff. It is focused on the greater good.]

22
Q

What does an abnormally thick nuchal fold mean during a first trimester screen (NT + maternal serum markers)?

A

Increased likelihood of an aneuploidy

[Recall that a nuchal translucency is a screening tool and is not diagnostic. The result is given in a ratio format to express the risk of an aneuploidy. Therefore, you cannot tell with certainty that the fetus has trisomy 21. This screening tool, does not screen for a neural tube defect.]

23
Q

A person presents to the clinic for evaluation, experiencing vaginal bleeding at 8 weeks gestation. They have O negative blood. Which plan of action is most appropriate?

A

order a vaginal probe ultrasound and administer 50 mcg of RhoGAM

[Given that this patient is 8 weeks, you would want to perform a TVUS as the uterus is still a pelvic organ until approximately 12 weeks.

Given the patient’s negative Rh status with early vaginal bleeding, it is best to proceed with administration of rhoGAM. 50mcg dose of rhoGAM can be used for 1st trimester events and protect against a fetomaternal bleed of 2.5mL RBC, because the mean RBC mass of the first trimester fetus is small (1.5mL at 12 weeks).]

24
Q

The clinician should proceed with further investigation if fetal heart tones are not auscultated by handheld Doppler by how many weeks gestation?

A

12 weeks

25
Q

A person had a positive pregnancy test and then a significant amount of vaginal bleeding a week later. At the clinic, an ultrasound shows an empty uterus. Which of these diagnoses is most accurate to describe this situation?

A

Complete abortion

[-Threatened abortion. This general term refers to bleeding in early pregnancy. Threatened abortion is often used as a diagnosis of exclusion.
-Incomplete abortion. These terms mean bleeding + pain + an open cervix. These terms are usually used when there is clinical certainty that the pregnancy loss is in progress.
-Missed abortion. This term is usually used when there is no bleeding or pain AND no cardiac activity, even though the pregnancy is advanced enough that there should be cardiac activity.
-Complete abortion. This term is usually used when all pregnancy products have been expelled.]

26
Q

A person is 5 weeks 2 days by sure LMP and has had a small amount of spotting. The patient is physiologically stable and has not had any pain.

An ultrasound shows:
-Presence of an intrauterine gestational sac and yolk sac
-No embryonic pole visible

Which of the following is accurate concerning the location and viability of the pregnancy?

A

The pregnancy is likely to be intrauterine. We cannot determine viability until we can visualize an embryonic/fetal pole and cardiac activity.

[The presence of a gestational sac and yolk sac in the uterus make an ectopic unlikely. The only way to determine viability is with the presence of cardiac activity.]

27
Q

A patient has vaginal bleeding, a positive urine pregnancy test, and an uncertain menstrual history. The serum beta hCG result is 1,000.

Given that beta hCG level, what is a transvaginal ultrasound likely to show?

A

A gestational sac and possibly a yolk sac but no embryonic pole.

[Gestational sac- seen at 1,000 hCG

Yolk sac- seen between 1,000-7,200 hCG

Embryonic pole- seen between 7,200-10,800

Cardiac activity is not typically seen until >10,800]

28
Q

Which of these clinical assessment elements aligns with molar pregnancy? [select all that apply]

a) Excessive nausea and vomiting
b) Minimal pregnancy symptoms
c) Lower than expected levels of beta hCG
d) Uterus larger than expected for gestational age
e) Brownish-colored vaginal bleeding
f) Empty uterus on ultrasound

A

a) Excessive nausea and vomiting
d) Uterus larger than expected for gestational age
e) Brownish-colored vaginal bleeding

[Higher than expected levels of beta hCG are common with molar pregnancies, Characteristic molar pregnancy features can be seen on US.]