Module 3 First Trimester Unit A-D Flashcards

1
Q

What symptoms might make a person suspect they are pregnant?

A

Presumptive elements=Subjective

Examples: Amenorrhea, Breast tenderness, enlargement, tingling, changes in shape/color, Fatigue, Nausea/vomiting, Urinary frequency/nocturia, Perception of fetal movement, Pigmentation changes, Sustained basal body temperature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What signs might make a clinician suspect a patient is pregnant?

A

Probable elements=Objective

Examples: Enlargement of abdomen or uterus, Pelvic exam changes: Chadwick’s, Goodell’s, Hegar’s, or Piskacek’s signs, Ballottment, Palpation of fetal outline, fetal movements, or uterine contractions, Positive pregnancy test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does a clinician definitively diagnose pregnancy?

A

Pregnancy can be confirmed through positive elements (cannot be from anything else) such as:
-Audible fetal heart tones
-Sonographic evidence of pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

When should a clinician use urine pregnancy testing vs. serum pregnancy testing? Serum quantitative vs. qualitative?

A

Qualitative urine pregnancy tests are used most often in the office, and serum pregnancy tests are used for special circumstances.

-Serum qualitative tests are done with urine is unavailable, and blood is already being sent.
-Serum quantitative is used when there is doubt about the health of the pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Why is a false negative urine pregnancy test more likely than a false positive urine pregnancy test?

A

The test could be taken too early to detect hcg.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

How can quantitative beta hCG patterns assist in clinical decision-making?

A

-HCG levels should double every 48-72 hours. If they don’t, this can indicate an embryo that is not developing properly or an ectopic.
-If higher than expected, could indicate multiples or molar pregnancy.
-Cannot be used to date pregnancy, and needs to be serial.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

How do you calculate an estimated date of birth using menstrual dates/Naegele’s Rule?

A

If 28 day cycle, take LMP + 7 days - 3 months + one year=due date.
Must have 28 day cycle that is regular. (If greater than 28 days, add days. If less than, subtract days)
Not on birth control or breastfeeding.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

In which clinical situations is ultrasound-based pregnancy dating clinically preferable?

A

-Cannot remember the first day of LMP
-LMP was unusual in some way (shorter, longer, lighter, heavier than expected or came at a time different than it was expected)
-Conceived while using hormonal contraception
-Breastfeeding at the time of conception
-There is a question about the health or development of the pregnancy because of spotting, the uterus is smaller than expected, or pregnancy symptoms have stopped unexpectedly. An ultrasound would then be for dating and for assessing the health of the pregnancy. Vaginal if <12 weeks suspected, abdominal if >12 weeks by clincal assessment.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

When should you change an estimated date of birth based on a subsequent ultrasound?

A

If <9 weeks gestation, change if greater than 5 days difference.
If 9-13.6 weeks gestation, change if greater than 7 days difference.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How will you incorporate shared decision-making in the decision about menstrual vs. ultrasound dating?

A

Pros of ultrasound: Less chance for a unncessary post-dates induction, maternal bonding, low risk.

Cons: Midwifery hallmark is low intervention unless necessary, they are vaginal which can be uncomfortable/traumatic, some insurance only covers a limited number of ultrasounds so it might be costly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How will you use bimanual exam results to assess gestational age in the first trimester?

A

6 weeks: small orange or pear.
8 weeks: naval orange
10-12 weeks = grapefruit
16 weeks= 3cm above pubic bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the elements of an initial obstetric history and physical exam that clinicians should assess? Why is each of them important? (In other words, don’t just memorize the list; think about why they matter.)

A

Height, weight, BMI, blood pressure, head-to-toe (if not done recently), assessment of uterus size.

Clinical pelivimetry is controversal and not routinely done.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the principles of prescribing for pregnant people?

A

Choose the lowest dose, for the shortest time, with the most evidence.
When possible, use a single medication as opposed to combination products.
Weigh the risks vs. benefits and include the patient in the decision-making process.
If possible, do not prescribe drugs during the first trimester.
When appropriate, prescribe topical instead of systemic drugs.
If the pregnant person is already taking a medication, discontinue only if the medication is harmful to the pregnancy and only if safe to do so. Some maternal conditions can be more dangerous if they are untreated (e.g. asthma, depression), compared with the risks of medication exposure during pregnancy.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How will you determine if a medication is safe for a person to continue during pregnancy?

A

Briggs on Lexicomp!
Compatible = The human pregnancy experience, either for the drug itself or drugs in the same class or with similar mechanisms of action, is adequate to demonstrate that the embryo–fetal risk is very low or nonexistent. Animal reproduction data are not relevant.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What labs do clinicians order as part of the initial obstetric panel?

A

Urine culture, CBC, RPR, MMR, blood type (RH factor), Hepatitis C/B, HIV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

How do clinicians record obstetric history using the GTPALM system?

A

G= How many pregnancies.
T: Term (37+ weeks)
P: Preterm (20-27 weeks)
A: Abortion (elective and spontaneous)
L: Living
M: Muliples (1= one set of twins)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

How do clinicians assess maternal well-being at subsequent/routine interval prenatal visits during the first trimester?

A

Blood pressure, weight, urine by dipstick (if indicated), evaluation of discomforts.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How do clinicians manage common discomforts in the first trimester, including subjective and objective data collection, development of assessment/differential diagnoses, determination of normalcy, development of a plan, and patient education? (You should be able to navigate that process for each of the common discomforts listed below.) ADD SLIDES ABOUT EACH DISCOMFORT. ANOTHER DECK MAYBE?

A

Shortness of breath
Urinary frequency
Nausea and vomiting
Heartburn
Breast tenderness/enlargement
Fatigue
Bleeding gums

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What subjective and objective findings would reassure you that a pregnancy is intrauterine and developing as it should be, even though a patient is experiencing first trimester bleeding?

A

Normal rising HcG, gestational sac and yolk in uterus.
Painless bleeding.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What are the subjective and objective data that you must assess to investigate the possibility of serious causes of first trimester bleeding such as ectopic pregnancy, molar pregnancy, and incomplete/inevitable early pregnancy loss?

A

Subjective: Ectopic and loss (painful), increased n/v (molar)
Objective: No yolk sac/pole/etc in uterus, abnormal hcg levels (higher for molar or lower than expected for loss and ectopic).. Bright red bleeding for ectopic or loss, dark brown for molar.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is the role of serial quantitative beta hCG testing in the setting of first trimester bleeding?

A

If betas are not rising normally, could indicate a embryo that is not growing in conjunction with the bleeding.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What are the less serious causes of first trimester bleeding and how will you assess for those?

A

-Subchorionic hemorrhage: Painless bleeding typically week 8-10, beta rises normally, seen on u/s.
Implantation bleeding: Roughly 2 weeks after ovulation, small amount for short amount of time, too early to see anything on ultrasound, betas would rise normally.
-Cervical irritation from infection or intercourse: Small amounts, irritation seen on cervix, no u/s findings, STI testing may be indicated.
-Fibroids/polyps: Uterus may be enlarged, will see on u/s, no conern if small, beta would rise.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

In which situations will you manage first trimester bleeding collaboratively with a physician colleague?

A

Ectopic and molar.

24
Q

How will you remain patient-centered, promote health equity, and provide anticipatory guidance to patients experiencing first trimester bleeding?

A

-Don’t use terms like “failed”
-Don’t assume their feelings surrounding the pregnancy. “How do you feel about this?”
-Mindful that some patients can’t leave work or pay for multiple lab draws or ultrasounds.

25
Q

For a patient 5 weeks from a sure LMP who has an ultrasound that does not show a definitive intrauterine pregnancy, what are the differential diagnoses? How will you proceed clinically?

A

Potential ectopic, but also could be too early to see.
Would do serial hcg and ultrasounds.
Give ectopic precautions.

26
Q

How would you interpret a situation in which a person is 7 weeks from a sure LMP whose beta hCG is 1,200 and transvaginal ultrasound shows no fetal pole?

A

You should be able to see something in the uterus once the hcg is >1,000 and a heartbeat once it is >10,000. HCG is very low for this gestation. This would be a blighted ovum or ectopic and options for management (expectant management, miso or D/C) would be given. Refer to physician.

27
Q

How will you decide whether/when to attempt to hear fetal heart tones with a Doppler in early pregnancy?

A

Most of the time you cannot hear prior to 12 weeks, but potentially as early as 10/11.
Discuss with patient and make the decision together. If they opt to try, and you cannot hear anything, have them return in a week.

28
Q

What are the prenatal genetic testing options in the first trimester?

A

NIPT.
Blood draw for maternal serum markers + NT.
Blood draw #1 of integrated or sequential.

29
Q

Which first trimester prenatal genetic testing options are screening tests and which are diagnostic?

A

Screening: NT, NIPT, quad, integrated and sequential screens.
Diagnostic: Amnio (later), CVS (10-14 weeks).

30
Q

For which conditions do the first trimester prenatal genetic testing option test? Which conditions do they NOT test for?

A

NIPT: T21, T13, T18, some do sexual like Turners, etc. (Anueploidy)

Does NOT test for structural abnormalities or neural tube defects.

31
Q

What are some techniques to avoid giving a patient a long lecture of options and details about each? i.e. how will you remain patient-centered in your counseling?* ADD SLIDES ABOUT SPECIFIC GENETIC TESTS

A

“Do you have an initial idea of the genetic testing decision you would feel comfortable with?”
“Can you say more about what makes that option most appealing?”

32
Q

What are the highest priority questions to ask a patient in the first trimester to assess their nutrition learning needs? Why did you select those questions?

A

Ask some general questions about the person’s comfort with nutrition concepts, their patterns of home cooking vs. restaurant or fast food, general food preferences, and who in their household shops and cooks.

Does the person have a history of disordered eating, bariatric surgery, underweight/overweight/obese, or closely spaced pregnancies? Is the person coping with food or housing insecurity or interpersonal violence? Does the person follow a vegetarian or vegan diet or have lactose intolerance?

33
Q

How will you help a person maximize nutrition as much as possible even if they are experiencing nausea and vomiting?

A

Ideally we want more B vitamins and protein, but emphasize it’s okay to just eat what they can. They do not need extra calories this trimester.

34
Q

What are the risks associated with getting listeriosis or toxoplasmosis during pregnancy?

A

Listeria (Bacterial): Stillbirth, miscarriage, and newborn deaths.
Toxo (Parasite): Blindness, mental illness, seizures.

35
Q

What can pregnant people do to avoid getting listeriosis or toxoplasmosis?

A

-Wash fruits and vegetables (avoid precut if possible), heat deli meats and hotdogs, eat pasturized dairy, avoid smoked seafood.
-Get someone else to manage the litterbox, but if you need to, wear gloves and a mask and wash hands afterwards. Likelihood of transmission if an exclusively indoor cat is low.
-Gardeners should wear gloves.
-Avoid raw pork, raw shellfish, drinking unfiltered water.

36
Q

What advice should you give regarding eating fish during pregnancy?

A

Avoid high mercury fish: (To Keep Me Safe & Soothe Our Tummy)
-Tuna, bigeye/steak
-King mackerel
-Marlin
-Shark
-Swordfish
-Orange roughy
-Tilefish (Gulf of Mexico)

Limit moderate to 1 serving a week: MahiMahi, halibut, Tuna, rockfish, monkfish, etc.

Others you can eat 2-3 times a week: Salmon, shellfish, light tuna etc.

37
Q

What advice should you give regarding caffeine intake during pregnancy? How will you incorporate shared decision-making in the conversation?

A

Ideally less than 200mg of caffeine daily (one 12oz cup) but the official statement is that consuming that amount of caffeine does not appear UNSAFE, which is a tricky statement.

38
Q

What fetal growth and development milestones would you share with a patient? How will you decide what to share?

A

Ask patients what they are interested in knowing. Many will have apps.

39
Q

What warning signs should you advise a person in the first trimester to report promptly?

A

Bleeding, painful uterine cramping, severe n/v.
Temperature >100.4, difficulty breathing, chest pain, swelling redness of leg, suicidal thoughts.
Whenever they feel something is “off.”

40
Q

If your practice follows a traditional prenatal visit schedule, when will you ask the person to schedule their next visit?

A

Four weeks later.

41
Q

What U/A is considered abnormal and needs treatment?

A

> 100,000 need to treat

42
Q

What changes do we expect to see in a CBC during first trimester of pregnancy?

A

All decrease during pregnancy

Hgb: >11 for pregnancy
Hct: 36.1-44.3
MCH: >27?
MCV: 80-100

43
Q

What is the expected result of antibody screening in pregnancy? How should the CNM respond with an abnormal result?

A

An antibody screen evaluates for antibodies in the mother’s blood that might cross the placenta and attack fetal red blood cells, causing hemolytic disease of the newborn.

Refer to physician if positive.

44
Q

What is the difference between a positive antibody vs. a positive antigen (HsbAG) of Hep B?

A

Positive Antibody means they are vaccinated.
Positive antigen (HsbAG) means they have Hep B

45
Q

How should the CNM respond if a patient has a positive result for RPR?

A

RPR/VDRL= Syphilis

Respond by retesting with a FTA-ABS

46
Q

What is the expected results of a TSH in the first trimester?

A

Because HCG also stimulates T3 and T4 production, TSH should decrease in pregnancy. Therefore, our threshold is lower:
-Non-pregnant adult reference range for TSH = 0.34 - 4.25
-First trimester reference range for TSH = 0.6 - 3.4 (some use 4.0 as upper limit)

47
Q

Explain the NT/serum screen.

A

-Noninvasive; does not risk fetal harm
-Does not determine fetal sex
-Positive results (abnormally thick nuchal fold or abnormal serum markers) require confirmatory testing
-In some settings, after the NT/serum screen, patients can choose to proceed to diagnostic testing OR have additional serum markers drawn in the second trimester OR do no additional testing

48
Q

Explain the cell-free DNA/NIPT/NIPS

A

-Noninvasive; does not risk fetal harm
-Can determine fetal sex
-Positive results require confirmatory testing
-Very high negative predictive value (a negative test is quite reassuring that the fetus does NOT have an aneuploidy)
-Higher positive predictive value (a positive test is likely to be a true positive) compared with traditional genetic screening tests
-Flexible timeframe of test (anytime between 10 weeks and term) allows for information early in pregnancy (which can be beneficial for people who might not continue the pregnancy) AND allows for information later in pregnancy for those who are late to care

49
Q

What subjective and objective data may be seen with a molar pregnancy?

A

Excessive n/v, high hcg, brownish bleeding, uterus larger than expected.

50
Q

If a patient requires Rhogam in the first trimester, how much should be given?

A

50mcg in first trimester

51
Q

How can the hCG levels be affected in an ectopic, impending miscarriage?

A

They are often lower than expected for gestational age and/or they do not rise as expected. This is not definitive of an unhealthy pregnancy

52
Q

How can the hCG levels be affected in a multiple gestation or molar pregnancy?

A

Will often but not always be higher than expected

53
Q

How can quantitive hCG be used?

A

It can be used to diagnose pregnancy and help determine the possible health of pregnancy but cannot definitively date a pregnancy. We must determine an accurate GA and assess hCG in a serial manner (q2-3d).

54
Q

How are the trimesters generally defined?

A

1st: 1-13w
2nd: 13-28w
3rd: 28-40w

55
Q

What factors must be present for Naegel’s rule calculation to be accurate?

A

Has a known LMP
Has regular cycles
Did no conceive on hormonal BC or BF
Has a clinical picture that fits

56
Q
A