Module 3 - Repro Flashcards
What are the major reproductive hormones in females?
estrogen, progesterone, LH, FSH, and GnRH
How does the Hypothalamic-Pituitary-Gonadal (HPG) axis regulate female hormone production?
Hypothalamus releasing GnRH, which stimulates the anterior pituitary to secrete LH and FSH. Act on the ovaries to regulate the production of estrogen and progesterone.
What are the phases of the menstrual cycle and the hormones involved?
Follicular phase
Ovulation
Luteal phase
The primary hormones are FSH, LH, estrogen, and progesterone.
What are the functional units of the ovary?
Follicles
What is the name of the process that produces female gametes?
oogenesis.
What is the 2-cell 2-gonadotropin hypothesis?
Estrogen production in the ovaries requires the interaction of theca, granulosa cells, LH and FSH. LH stimulates theca cells to produce androgens, then converted into estrogen by granulosa cells under the influence of FSH.
What are the two cycles that make up the ‘menstrual’ cycle?
Ovarian cycle (follicular phase, ovulation, and luteal phase)
Uterine cycle (menstruation, the proliferative phase, and the secretory phase).
What is Folliculogenesis?
The maturation process of ovarian follicles,
What is a Primordial Follicle?
An early stage follicle consisting of an immature oocyte surrounded by a single layer of flattened granulosa cells, present in the ovaries from birth.
What is a Preantral Follicle?
A developing follicle, multiple layers of granulosa cells surrounding the oocyte, no antrum.
What is an Antral Follicle?
A more developed follicle containing an antrum, with the oocyte surrounded by layers of granulosa and theca cells.
What is the Corpus Luteum?
A temporary endocrine structure formed from the remnants of the follicle after ovulation, which secretes progesterone and estrogen to prepare the uterus for possible pregnancy.
What is a Gonadotropin?
A hormone that stimulates the activity of the gonads
What does LH stand for, and what is its function?
Luteinizing Hormone
Stimulates ovulation and the formation of the corpus luteum in females, and testosterone production in males.
What does FSH stand for, and what is its role?
Follicle-Stimulating Hormone
Promotes the growth of ovarian follicles in females and spermatogenesis in males.
What does GnRH stand for, and what does it do?
Gonadotropin-Releasing Hormone
Released by the hypothalamus to stimulate the pituitary gland to secrete LH and FSH.
What are Theca Cells?
Cells that surround the follicle and work with granulosa cells to produce estrogen precursors, primarily androgens.
What are Granulosa Cells?
Cells that surround and nourish the developing oocyte within the follicle and convert androgens into estrogen.
What are Androgens?
Steroid hormones that play a role in male traits and reproductive activity; they are also precursors for estrogen synthesis in females.