Module 2 - Resp Flashcards

1
Q

What is external respiration?

A

The movement of gases between the environment and the cells of the body.

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2
Q

What is internal respiration?

A

The movement of gases from the lungs, through the bloodstream, and to the cells.

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3
Q

What is the upper respiratory system, and what are its functions?

A

nose, pharynx, and associated structures. Functions include warming, humidifying, filtering air, olfaction (smell), and speech resonance.

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4
Q

What is the lower respiratory system, and what are its functions?

A

larynx, trachea, bronchi, and lungs. Functions involve protecting the airway, conducting air to the lungs, and enabling gas exchange.

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5
Q

What are alveolar pneumocytes, and what are their types?

A

Alveolar pneumocytes are cells in the alveoli.

Type 1: Simple squamous epithelial cells, forming the walls of the respiratory membrane.

Type 2: Simple cuboidal epithelial cells, producing surfactant to reduce surface tension.

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6
Q

What is Boyle’s Law?

A

The volume of a gas is inversely proportional to its pressure at a constant temperature. In respiration, as lung volume increases, pressure decreases, causing air to flow in.

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7
Q

What is the role of the pleura in the respiratory system?

A

The pleura are membranes surrounding the lungs and lining the thoracic cavity. They reduce friction during breathing and help keep the lungs expanded.

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8
Q

What is the function of the diaphragm in respiration?

A

The diaphragm contracts to increase the thoracic cavity’s volume during inhalation, decreasing pressure and drawing air into the lungs.

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9
Q

What is pulmonary circulation?

A

The process that conducts blood from the heart to and from the gas exchange surfaces of the lungs.

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10
Q

What are the three main factors that influence respiration?

A

Compliance (ease of lung expansion), airway resistance, and elastic recoil (lungs returning to their resting state).

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11
Q

What is airway resistance?

A

The opposition to the flow of air through the respiratory tract, which is influenced by the airway’s length, radius, and cross-sectional area.

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12
Q

What is elastic recoil?

A

The tendency of the lungs to return to their normal state after being stretched or filled with air. It counteracts compliance

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13
Q

What are bronchioles, and how do they function?

A

Small airways in the lungs that lack cartilage and are surrounded by smooth muscle, allowing them to regulate airflow by contracting and relaxing.

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14
Q

What is the role of surfactant in the lungs?

A

a detergent-like mixture of phospholipids and proteins that reduces surface tension within the alveoli, preventing their collapse and aiding in efficient gas exchange. Without surfactant, the alveoli would tend to collapse, making breathing difficult.

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15
Q

What is Dalton’s Law of Partial Pressures?

A

The total pressure of a mixture of gases is equal to the sum of the partial pressures of each gas.

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16
Q

What is Henry’s Law, and how does it relate to gas exchange?

A

The amount of dissolved gas in a liquid is proportional to the partial pressure of that gas above the liquid.

For respiration, it explains how oxygen and carbon dioxide dissolve in blood based on their partial pressures in the alveoli.

17
Q

What is Fick’s Law of Diffusion, and how does it apply to the alveoli?

A

Fick’s Law states that the rate of gas diffusion across a membrane is proportional to the surface area and the concentration gradient and inversely proportional to the membrane’s thickness.

In the alveoli, this means that a larger surface area and thinner membrane facilitate more efficient gas exchange.

18
Q

What is ventilation-perfusion coupling?

A

The relationship between the amount of air reaching the alveoli (ventilation) and the amount of blood reaching the alveoli (perfusion). For optimal gas exchange, these two processes must be closely matched.

19
Q

What is the role of hemoglobin in oxygen transport?

A

Hemoglobin, a protein in red blood cells, binds to oxygen molecules in the lungs and carries them to tissues throughout the body. Approximately 98.5% of oxygen in the blood is bound to hemoglobin, forming oxyhemoglobin.

20
Q

What is the Haldane Effect?

A

How oxygen binds to hemoglobin in the lungs reduces hemoglobin’s ability to bind carbon dioxide and protons, facilitating their release and exhalation. In tissues, the release of oxygen increases hemoglobin’s capacity to bind carbon dioxide and protons, aiding in their removal.

21
Q

What is alveolar interdependence, and why is it important?

A

Structural support alveoli provide each other, preventing collapse. When one alveolus starts to collapse, surrounding alveoli recoil, pulling it open and maintaining overall lung stability.

22
Q

What is the Medulla Oblongata’s role in respiratory regulation?

A

It contains the Dorsal Respiratory Group (DRG) and Ventral Respiratory Group (VRG), which control the rhythm of breathing and the muscles involved in inspiration and expiration.

23
Q

What is the Dorsal Respiratory Group (DRG)?

A

A group of neurons located in the nucleus tractus solitarius in the medulla oblongata that primarily controls the muscles involved in inspiration.

24
Q

What is the function of the Pons Respiratory Center?

A

It fine-tunes the breathing pattern by integrating inputs from higher brain centers and peripheral sensory receptors, and modulates the activity of the DRG and VRG.

25
Q

What are Chemoreceptors?

A

Sensory receptors sensitive to changes in blood levels of carbon dioxide, oxygen, and pH, which send signals to the respiratory centers to adjust ventilation rates.

26
Q

What are Stretch Receptors in the respiratory system?

A

Located in the walls of the airways, these receptors detect lung inflation and send inhibitory signals to the medulla to end inspiration, preventing over-inflation.

26
Q

What is the Hering-Breuer Reflex?

A

A reflex triggered to prevent over-inflation of the lungs, mediated by stretch receptors sending signals to the medulla to stop inhalation.

27
Q

What is the difference between Obstructive and Restrictive Pulmonary Diseases?

A

Obstructive diseases impede airflow (e.g., asthma, COPD), while restrictive diseases limit lung expansion (e.g., pulmonary fibrosis, chest wall deformities).