Module 3 Buttarro Ch 171-184 Flashcards
A patient with a family history of amyotrophic lateral sclerosis (ALS) begins to have symptoms that include asymmetric weakness in the arms and difficulty walking. The neurologist recognizes these symptoms as characteristic of involvement of which portion of the nervous system?
a. Lower motor neurons (LMN)
b. Upper motor neurons (UMN)
c. Corticospinal tracts
d. Corticobulbar tracts
a. Lower motor neurons (LMN)
Lower motor neuron involvement and early LMN cell death leads to an insidious onset of asymmetric weakness that is evident initially in the limbs, usually in the arms.
Upper motor neuron cell death may result in hyperreflexia, spasticity, incoordination, and weakness.
Bulbar signs include dysarthria, dysphagia, and tongue fasciculations.
The corticospinal tracts are part of the UMN cells.
The spouse of a patient newly diagnosed with amyotrophic lateral sclerosis (ALS) asks about long-term care. What will the provider include when teaching the family about this disease?
a. Bowel and bladder function will eventually be lost.
b. Positive-pressure ventilation can prolong life.
c. Preventing malnutrition is a key element in care.
d. The nerves affecting sensation will die initially.
c. Preventing malnutrition is a key element in care.
Prevention of malnutrition may improve both the quality and length of life.
Bowel and bladder function and sensation remain intact.
Positive-pressure ventilation helps to relieve sleep disturbance.
A 35-year-old patient reports suddenly experiencing an asymmetric smile along with drooping and tearing in one eye. The patient has a history of a recent viral illness but is otherwise healthy. During the exam, the provider notes that there is unilateral full-face paralysis on the right side. What is the initial intervention for this patient?
a. Perform confirmatory diagnostic tests.
b. Prescribe oral corticosteroids.
c. Recommend wearing an eye patch.
d. Refer the patient to a neurologist.
b. Prescribe oral corticosteroids.
-Bell Palsy = Acute progressive UNILATERAL weakness of the facial nerve, caused by inflammatory proccess of unknown eitiology
-TREATED with CORTICOSTEROIDS within 72 hours of onset or IVIG
- a peripheral facial nerve condition
-self limiting
-typically occurs after recent viral infection (varicella, mono, flu, CMV)
-either side of the face can be affected.
-more common in last trimester of pregnancy
DIAGNOSED: based on history, don’t need MRI unless central lesion is suspected
central lesion sx = is asymmetrical weakness with numbness tingling and ABILITY o wrinkle for head
Bell palsy pt are UNABLE to wrinkle forehead, and UNABLE to close eyes
Patients may be instructed to tape the eye closed at night, but eye patches are not recommended.
What is recommended to prevent ophthalmic complications in patients with Bell’s palsy?
a. Acupuncture
b. Lubricating eye drops
c. Patching of the eye
b. Lubricating eye drops
Bell palsy pt are UNABLE to wrinkle forehead, and UNABLE to close eyes
Patients may be instructed to tape the eye closed at night, but eye patches are not recommended.
Exposure keratitis from drying of the eye can result in blindness. Lubricating eye drops should be used every 2 hours. Protective eyewear to prevent moisture loss is recommended.
Which symptoms may occur with Bell’s palsy? (Select all that apply.)
a. Alteration in taste
b. Decreased hearing
c. Drooling
d. Inability to open the eye
e. Tinnitus
a. Alteration in taste
c. Drooling
e. Tinnitus
Bell’s palsy may cause altered taste, drooling, and tinnitus. It causes increased sensitivity to noises and an inability to close the eye.
A patient exhibits visual field defect, ataxia, and dysarthria and complains of a mild headache. A family member reports that the symptoms began several hours prior. An examination reveals normal range of motion of the neck. What type of cerebrovascular event is most likely?
a. Hemorrhagic stroke
b. Hypertensive intracerebral hemorrhage
c. Ischemic stroke
d. Transient ischemic attack (TIA)
c. Ischemic stroke
NUCHAL rigidity is more common with hemorrhagic stroke
Ischemic stroke
- interruption of blood flow in the CNS
- occurs in one SINGLE event that resolves in a few hours
- DONOT typically have HA
- THROMBOLIC therapy (TPA) is given to patients with ischemic stroke.
- Sx depend on Location Middle artery=most common
1. LEFT Middle SX - RIGHT side face, right arm, right leg weakness, hemianopia = Losing sight in HALF of your visual field, (confrontation) with expressive (brocas) aphasia= difficulty speaking, but can understand
- Right: middle
- LEFT side face, arm, leg weakness with possible Henianopia
An elderly patient is brought to the emergency department after being found on the floor after a fall. The patient has unilateral sagging of the face, marked slurring of the speech, and paralysis on one side of the body. The patient’s blood pressure is 220/190 mm Hg. What is the likely treatment for this patient?
a. Carotid endarterectomy
b. Close observation until symptoms resolve
c. Neurosurgical consultation
d. Thrombolytic therapy
c. Neurosurgical consultation
This patient has signs consistent with hemorrhagic stroke and will need consultation with a neurosurgeon to determine whether surgical intervention will be beneficial.
Carotid endarterectomy is performed in patients with carotid stenosis and is used in patients with hemispheric ACVS (TIA).
Patients with TIA may be observed to monitor symptoms.
Hemorrhagic Stroke:
- sudden onset severe headache “thunderclamp”
- pain may radiate
- n/v
- NUCHAL RIGIDITY
- LOC
- typically caused by an aneurysm rupture or vascular malformations
A previously healthy 30-year-old patient is brought to the emergency department with signs of stroke. Diagnostic testing determines an ongoing ischemic cause. The patient’s spouse reports that symptoms began approximately 2 hours prior to transport. What is the recommended treatment?
a. Administration of low-molecular-weight heparin
b. Neurosurgical consultation for possible surgery
c. Observation for complications prior to initiating tPA
d. Tissue plasminogen activator (tPA) administration
d. Tissue plasminogen activator (tPA) administration
This patient meets the criteria for tPA administration and it should be begun within 4.5 hours after onset of symptoms. This patient has had symptoms for over 2 hours, so tPA should begin immediately.
LMW heparin is not indicated.
Neurosurgical intervention is recommended for patients with hemorrhagic stroke.
A previously lucid patient with early-stage Alzheimer’s disease is hospitalized after a surgical procedure and exhibits distractibility and perceptual disturbances that occur only in the late afternoon. The patient has difficulty sleeping at night and instead sleeps much of the morning. What is the likely cause of these symptoms?
a. Hyperactive delirium
b. Hypoactive delirium
c. Sundowner syndrome
d. Worsening dementia
c. Sundowner syndrome
Patients with dementia are at increased risk of sundowner syndrome, characterized by the symptoms above and which typically appear in late afternoon and early evening. Hyperactive delirium is manifested by agitation and restlessness. Hypoactive delirium includes patients with decreased alertness, lethargy, and slowed speech. Delirium and worsening of dementia would cause symptoms around the clock, not just in the late afternoon or evening.
An 80-year-old patient becomes apathetic, with decreased alertness and a slowing of speech several days after hip replacement surgery alternating with long periods of lucidity. What is
the most likely cause of these symptoms?
a. Anesthesia effects
b. Delirium
c. Pain medications
d. Stroke
b. Delirium
An acute presentation of these symptoms is most likely delirium since they alternate with lucid periods. The other causes may contribute to delirium by intensifying it.
An elderly patient has symptoms of depression and the patient’s daughter asks about possible Alzheimer’s disease (AD) since there is a family history of this disease. A screening evaluation shows no memory loss. What is the initial step in managing this patient?
a. Order brain imaging studies such as CT or MRI.
b. Perform genetic testing to identify true risk.
c. Prescribe a trial of an antidepressant medication.
d. Recommend a trial of a cholinesterase inhibitor drug.
c. Prescribe a trial of an antidepressant medication.
Elderly patients with depression who do not have other signs of AD may be given a trial of antidepressant medications initially in order to evaluate these symptoms. Brain imaging studies are not indicated initially. Genetic testing is not indicated. Once the degree of depression is determined and if other symptoms appear, an anticholinesterase inhibitor may be ordered.
A patient reports a recurrent sensation of spinning associated with nausea and vomiting. Which test will the provider order to confirm a diagnosis for this patient?
a. Electroencephalogram (ECG)
b. Holter monitoring and electrocardiogram
c. Neuroimaging with computerized tomography (CT)
d. The Hallpike-Dix positioning maneuver
d. The Hallpike-Dix positioning maneuver
Dizziness can be wither associated with Cardiac issue, eye issue of ear (vestibular issue= Vertigo) or brain (cerebellum)
Must determine if vestibular lesion done by performing Hallpike-Dix position maneuver to evaluate vestibular function
If seizure activity is suspected, an electroencephalogram will be ordered.
Holter monitoring and ECG are used if patients report syncope or lightheadedness.
Neuroimaging with CT is used when patients possibly have a central lesion which would present with difficulty balancing.
An older adult patient reports sensations of being off balance when walking but does not experience dizziness. The provider will refer this patient to which specialist for further evaluation?
a. Audiologist
b. Cardiologist
c. Neurologist
d. Otolaryngologist
c. Neurologist
This patient has problems of balance without dizziness, suggestive of a central neural lesion and should be referred to a neurologist.
Patients with vertigo are likely to have vestibular dysfunction and would be referred to an otolaryngologist and possibly an audiologist if hearing is affected.
Patients with syncope or lightheadedness are more likely to have an underlying cardiac disorder and would be referred to a cardiologist.
Following an upper respiratory infection, a patient begins to develop ataxia and distal paresthesias, along with oculomotor symptoms and double vision. Based on these presenting symptoms which type of Guillain-Barré syndrome (GBS) does this patient have?
a. Acute inflammatory demyelinating polyradiculoneuropathy (AIDP)
b. Acute motor axonal neuropathy (AMAN)
c. Classic Guillain-Barré syndrome
d. Miller Fisher syndrome (MFS)
d. Miller Fisher syndrome (MFS)
GBS-symmetric paresthesias and/or lack of weakness, typically starting in lower extremities and evolving ocer days or hours typically Patients with have HISTORY of Recent infection. Can spread up and affect respiratory muscles
DX with LP lookin for increased protein
Miller Fisher syndrome has oculomotor symptoms. Patients with this type tend to peak sooner and recover more completely and quickly.
Which diagnostic test helps confirm a diagnosis of Guillain-Barré syndrome (GBS) in a patient who is developing muscle weakness and paresthesias?
a. Lumbar puncture
b. MRI imaging
c. Nerve conduction studies
d. Screening for systemic infection
a. Lumbar puncture
A lumbar puncture is the most important confirmatory test showing albuminocytologic disassociation.
MRI imaging typically is not necessary unless there is concern for spine pathology but does not diagnose GBS.
Nerve conduction studies are not necessary for the diagnosis. Screening for systemic infection is based on history and does not diagnose GBS.
Which monitoring parameters are necessary when caring for a patient with Guillain-Barré syndrome (GBS)? (Select all that apply.)
a. Bladder scans
b. Cardiac telemetry
c. Imaging studies
d. Fever
e. Vital capacity measures
a. Bladder scans
b. Cardiac telemetry
d. Fever
e. Vital capacity measures
Urinary retention can cause discomfort and infection, so assessment of urinary retention is necessary. Cardiac telemetry is essential, as are measures of pulmonary function. Imaging studies are not essential.
A patient reports recurrent headaches occurring 1 or 2 times per month that generally occur with weather changes or when sleep patterns are disrupted. They are described as severe, with throbbing on one side of the head and sometimes accompanied by nausea. What is the recommended abortive treatment for this type of headache?
a. Gabapentin
b. Propranolol
c. Ergotamine tartrate
d. Topiramate
c. Ergotamine tartrate
Migraines typically are severe, described as pounding or throbbing accompanied by n/v, phono, photophobia, can be associated with identified triggers,
tx: *must rule our Cardiovascular problems, medications to treat headache are vasoconstrictors
Severe attacks
1. Triptans = first line abortive-may cause flushing or tinging
2. ergotamine-may cause nausea
mild-mod
-analgesiacs with antiemetics
moderate- severe
-triptans with nsaids (naproxen)
Propholactice tx taken every day
- Beta-blockers
- TCAs (elavil at bedtime)
- SNRIs - effexor
- anticonvulsants- topamax, valporate
The other medications are preventive medications and are used for patients having more than 4 per mo
A patient has recurrent cluster headaches and asks about abortive therapy. Which therapy is effective for most patients with cluster headaches?
a. Lithium
b. NSAIDs
c. Oxygen
d. Verapamil
c. Oxygen
Cluster headaches
- unilateral
- pts will wake up with it
- last 15-90 minutes
- can occur several times a day
- typically pts are restless and cannot sit still, moaning or crying
tx; Oxygen works as abortive therapy for cluster headaches in 75% of patients and should be inhaled at the start of an attack.
NSAIDs are not useful.
Lithium and verapamil work well as preventive medications for cluster headaches but are not given for abortive treatment.
Which medications may be useful in treating tension-type headache? (Select all that apply.)
a. Triptan drugs
b. Lithium
c. Muscle relaxants
d. NSAIDs
e. Oxygen
a. Triptan drugs
c. Muscle relaxants
d. NSAIDs
Tension HA:
- feeling like a tight band across head
- do not have n/v
- nagging
- common triggers are headache
- not exacerbated by activity
Triptan drugs, muscle relaxants, and NSAIDs may all be used to treat tension-type headaches.
Lithium and oxygen are not used.