Mod 4: Buttaro Ch 154-170, 195-170 Flashcards

1
Q

A patient injures an ankle while playing soccer and reports rolling the foot inward while falling with immediate pain and swelling of the lateral part of the joint. The patient is able to bear weight and denies hearing an audible sound at the time of injury. What does this history indicate?

a. Likely ankle sprain with a possible fracture
b. Mild ankle injury without fracture
c. Mild soft tissue injury only
d. Serious ankle injury with certain fracture

A

a. Likely ankle sprain with a possible fracture
inversion- rollin sole inward toward midline
at risk for lateral ligaments injury
eversion-rolling sole outwards away from
midline
-at risk for deltoid ligament injury
**Immediate swelling, bruising of the joint raises the index of suspicion for a fracture or a substantial amount of joint involvement. will need xrays to confirm

***any pop sounds indicate a more serious injury

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2
Q

A patient who is a distance runner reports pain in one heel that is worse in the morning and
seems to improve with exercise. The provider notes localized swelling and a bony prominence
at the heel. What is the initial treatment for this condition?
a. Cessation of all sports activities and exercise
b. Crutches and partial weight bearing
c. Physical therapy for ultrasound therapy
d. Referral to an orthopedist for MRI and evaluation

A

a. Cessation of all sports activities and exercise

This patient has symptoms consistent with Achilles tendonitis.

Immediate cessation of sports and exercise is the first step in management.
**if tear= emergency, classic sign = I thought i got shot in my calf, refer to ortho

Crutches and partial weight bearing may be indicated if symptoms do not improve with rest and NSAIDs.

Physical therapy is used as adjunctive therapy. Symptoms that do not improve require referral.

Stretching and using heal lift inserts

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3
Q

A patient has pain on the plantar aspect of the heel with weight bearing after rest. The pain is worsened with dorsiflexion of the foot. What is the initial treatment for this patient?

a. A series of steroid injections
b. Avoiding all high-impact activities
c. Night splints
d. Wearing flat shoes only

A

b. Avoiding all high-impact activities

The fascia supports the arch with movement like jumping and running

sx: pain with weight bearing the 1st thing in am

The initial treatment includes avoiding all high-impact activities. A single steroid injection may be given with subsequent injections if no improvement.

Night splints are part of second-tier treatment.
Flat shoes should be avoided.

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4
Q

A provider discovers a bone tumor as an incidental finding on a radiograph in a patient who has sustained an injury to a ligament. The patient has not had pain prior to the injury. What will the provider do next?

a. Consult with an orthopedic specialist
b. Order a chest CT and full body scan
c. Refer the patient to for a bone biopsy
d. Repeat the radiograph in 3 to 6 months

A

d. Repeat the radiograph in 3 to 6 months

Latent bone tumors are usually discovered as incidental findings during evaluation for musculoskeletal injury. OFTEN BENIGN If the injury is the source of pain, the radiograph may be repeated in 6 to 12 months to determine whether it is increasing in size. WHICH IS A CONCERN FOR MALIGNANCY

Consultation with an orthopedic specialist, referral for a biopsy, and further testing with chest CT or full body scanning are done if there is suspicion of an active tumor.

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5
Q

A patient reports persistent lower back pain and constipation. A digital rectal examination
reveals a mass at the sacrum. What will the primary care provider do to manage this patient?
a. Order spinal radiographs in 3 months
b. Perform an MRI of the sacrum
c. Refer the patient to an oncologist
d. Schedule the patient for a biopsy
GRADESMORE.COM

A

c. Refer the patient to an oncologist

This patient has a chordoma based on symptoms (low back pain, constipation) and a palpable mass coming out of the sacrum. A referral to an oncologist is necessary. These tumors have a significant risk for malignancy, so waiting 3 months is not an option.

bone is common sites for mets especially cancer of breast, prostate, kidney thyroid and lung

sx of bone pain that are concerning:

  • bone pain worse at night
  • pain longer than 6 months
  • progressing in severity
  • and/or swelling

3 most common bone lesions:

  1. osteosarcoma (cancer that begin in bone cell often in long bones of arms/legs)
  2. Chordoma: which is a type of sarcoma with a predilection for the sacrum,
  3. Multiple myeloma- cancer of the plasma cell (WBC in bone marrow)
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6
Q

Which treatments may be used to manage bone pain in patients with bone tumors? (Select all that apply.)

a. Bisphosphonates
b. Exercise
c. External beam radiation
d. Massage
e. Vertebroplasty

A

a. Bisphosphonates
b. Exercise
c. External beam radiation
e. Vertebroplasty

Bisphosphonates can decrease pain by preventing growth and development of existing and new bone lesions.

Exercise is useful to maintain function and reduce pain.

External beam radiation is useful in most patients.

Vertebroplasty involves injecting bone cement to stabilize bone.

Massage is not recommended.

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7
Q

A patient experiencing shoulder pain is seen by an orthopedic specialist who notes erythema, warmth, and fluctuance of the shoulder joint. What is the next step in treatment for this patient?

a. Admit to the hospital for intravenous antibiotics.
b. Inject lidocaine into the joint and reassess in 5 to 10 minutes.
c. Order a plain radiograph of the shoulder to identify possible fracture.
d. Perform a shoulder ultrasound to further evaluate the cause.

A

a. Admit to the hospital for intravenous antibiotics.

Bursa = sac lined with a membrane that produces and contains synovial fluid that provides lubrication and facilitates smooth movements b/w tissue of extremities

MOST COMMON: SHOULDER, HIP, KNEE, HEEL

can become septic (red, hot swollen = Immediate referral is indicated for patients who present with symptoms consistent with septic bursitis, such as with the symptoms above.
-can do synovial aspiration to dx

Lidocaine is injected into a painful joint to evaluate for improvement to determine whether bursitis or tendonitis is present as a result of impingement.

This exam is not consistent with fracture. An ultrasound is not indicated.

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8
Q

A patient with elbow pain without localized erythema or warmth is diagnosed with bursitis of the elbow and serum laboratory results are pending. What is the initial treatment while waiting for these results?

a. Aspiration of the bursal sac for culture
b. Corticosteroid injection into the bursal sac
c. Elbow pads, NSAIDs, rest, and ice
d. Physical and occupational therapy

A

c. Elbow pads, NSAIDs, rest, and ice

bursitis without signs of septic treated with
Initial therapy includes conservative measures for comfort. but must draw CBC, ESR, CRP

Until infection is suspected, based on the white blood count and inflammatory markers, and without localized signs of infection, aspiration of the bursal sac is not indicated.

Corticosteroids should not be injected into the bursal sac until infection has been excluded. Physical and occupational therapy should not precede comfort measures.

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9
Q

What are included in the initial management of bursitis of the heel? (Select all that apply.)

a. Activity modification and bracing
b. Closed heel shoes to prevent further injury
c. Corticosteroid injections
d. Nonsteroidal anti-inflammatory medications
e. Rest, ice, compression, and elevation

A

a. Activity modification and bracing
d. Nonsteroidal anti-inflammatory medications
e. Rest, ice, compression, and elevation

Activity modification and bracing, NSAIDs, and RICE are all used initially to treat heel bursitis. Patients should wear open-heeled shoes. Corticosteroid injections should be used cautiously to prevent rupture of the Achilles tendon.

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10
Q

Which cause is implicated in patients with fibromyalgia syndrome (FMS)?

a. Autoimmune disease
b. Central nervous system dysfunction
c. Muscle dysfunction
d. Viral disease

A

b. Central nervous system dysfunction

fibromyalgia-wide spread muscle skeletal pain, fatigue, non restorative sleep, DEPRESSION, ha, gi problems
-considered a rheumatologic
condition
-unclear cause
DX: wide spread pain > 7/10
generalized pain in at least 4-5 regions
pain present for at least 3 months

Although the cause of FMS is unclear, current research suggests a CNS cause and not muscle, autoimmune, or viral causes.

tx with low dose TCA= amytriptaline 10mg taken 2-3 hours before bedtime

or SNRIs= fluoxetine, duloxetine

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11
Q

When counseling a patient about the long-term effects of fibromyalgia syndrome, what is important to include in teaching?

a. A multidisciplinary approach to treatment is most effective.
b. Eventual damage to muscles and joints will occur.
c. Exercise may cause discomfort and damage to muscles.
d. Medications are useful for controlling and preventing symptoms.

A

a. A multidisciplinary approach to treatment is most effective.

A multidisciplinary approach to FMS management can help with pain management, stress,
and exercise. Although patients experience pain, damage to tissues does not occur. Exercise
may be painful but does not cause damage. Medications help alleviate some, but not all symptoms.

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12
Q

Which are symptoms associated with fibromyalgia? (Select all that apply.)

a. Gastrointestinal complaints
b. Hepatosplenomegaly
c. Musculoskeletal pain
d. Nonrestorative sleep
e. Renal complications

A

a. Gastrointestinal complaints
c. Musculoskeletal pain
d. Nonrestorative sleep

Fibromyalgia may cause GI complaints, musculoskeletal pain, and nonrestorative sleep. Hepatosplenomegaly and renal complications are not associated with fibromyalgia.

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13
Q

A postmenopausal female patient has a blood test that reveals hyperuricemia, although the patient has no symptoms of gout. What will the provider do initially?

a. Ask the patient about medications and medical history
b. Begin therapy with colchicine and an NSAID
c. Recommend a low-purine, alcohol-restricted diet
d. Treat for gout prophylactically to prevent a flare

A

a. Ask the patient about medications and medical history

Patients without symptoms of gout but with hyperuricemia do not need treatment, since most of these patients will never have a gout flare. It is important, however, to determine the cause of this finding and correct it if possible, since it is a risk factor for gout. Certain medications and medical conditions can predispose patients to gout.

Colchicine and NSAIDs are used to treat symptoms of gout.

Dietary changes are not necessary and are difficult to follow.

Prophylaxis for prevention of flares is for patients who have gout and who are between flares.

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14
Q

A patient with gout and impaired renal function who uses urate-lowering therapy (ULT) is experiencing an acute gout flare involving one joint. What is the recommended treatment?

a. Administration of intraarticular corticosteroid
b. Discontinuing ULT while treating the flare
c. Oral colchicine for 5 days
d. Therapy with NSAIDs begun within 24 hour

A

a. Administration of intraarticular corticosteroid

Intraarticular steroids are practical and beneficial when only one or two joints are involved

Gout- chronic disease caused by a built of urate in the blodd= hyperurecemia
urate= product of purine metabolism, insoluable to humans, typically gets excreted in urine
-excess urate can deposit in joints and lead to pain.

SX: rapid onset, red, hot, swollen joint, that increases in pain, pain often begins at night

typically occurs 1st in metatarsal joint (toe)
more common in diet consisting of Alcohol, overeating, fasting diuretics

MEN typically have one joint effected episodes
POSTMENAPAUSAL WOMEN- it will affect less than 4 joints

TX: Focused on treating acute attack with oral corticosteroids or NSAIDS with in 24-48 of attack or chochicine

Long-term= use of urate lowering agents- daily use of Allupurinol not to be used during an attack because it will prolong it. SART 5-6 weeks AFTER attack Must have urate level less than 6

NSIADs are contraindicated in patients with renal disease and colchicine should not be used in those with low glomerular filtration rates.*

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15
Q

A patient experiences a second gouty flare and the provider decides to begin urate-lowering therapy (ULT). How should this be prescribed?

a. Begin with a high-loading dose and gradually decrease.
b. Start ULT during the current flare for best results.
c. Start ULT in 5 weeks along with an anti-inflammatory drug.
d. ULT should be suspended during future gouty flares.

A

c. Start ULT in 5 weeks along with an anti-inflammatory drug.

Beginning therapy with a urate-lowering drug during an acute flare will prolong the flare.
Typically, ULT is begun 5 to 6 weeks AFTER A FLARE a flare and should be given with an anti-inflammatory drug, since the initial period of ULT administration is associated with flares.

ULT dosing should start low and gradually increase.

It is not recommended to stop ULT during future flares, but to treat those flares while continuing the ULT.

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16
Q

A patient reports the sudden onset of pain, redness, and swelling in one knee joint but denies a fever. The provider elicits exquisite pain with manipulation of the joint and notes no decrease in pain when the joint is at rest. Which is the likely cause of this arthritis?

a. Bacterial infection
b. Gout
c. Lyme disease
d. Rheumatoid arthritis

A

a. Bacterial infection

Biggest symptom = pain at rest and pain relieved by medicine
fever is not always present

septic arthritis = emergency
casued by autoimmune, gout, infection

**if pain is continued despite therapy =sign of infection

synovial sites = most common due to more likely to experience trauma that can damage joint and lead to increase risk of organisms affecting area

***STAPH= MOST COMMON
However can have STD organism cause septic arthritis

Will need synovial fluid analysis to confirm BACTERIAL cause
blood cultures will not show anything

Septic arthritis is usually painful both with movement and at rest and is accompanied by swelling and erythema. Fever is not always present. The other causes of arthritis are not painful at rest.

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17
Q

An adolescent patient reports intermitted pain and swelling in various joints on the right side including the knee, elbow, wrist, and ankle. A physical examination reveals tenosynovitis and a maculopapular rash. Which diagnostic tests will be most helpful in determining a diagnosis in this patient?

a. Blood cultures and a complete blood count
b. Cultures of the urethra, pharynx, cervix, and rectum
c. Skin lesion scrapings and cultures
d. Urine cultures and renal function studies

A

b. Cultures of the urethra, pharynx, cervix, and rectum

most common cause of from bacteria, fungi, virus, and STD

This patient has signs of gonococcal arthritis. Cultures of the urethra, pharynx, cervix, and rectum will be positive in 80% of patients with this infection.

Blood cultures are likely to be negative. Culturing skin lesions is not helpful. Renal involvement is not part of this infection.

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18
Q

A patient has marked swelling of a shoulder joint with erythema and severe pain. The provider suspects a bacterial cause. Which culture will be most helpful to determine the cause of these symptoms?

a. Blood culture
b. Synovial fluid culture
c. Urethral culture
d. Urine culture

A

Synovial fluid culture is the most important exam for diagnosis of septic arthritis.

Blood culture may be positive in only 10% of cases.

Urethral culture is performed if gonococcal arthritis is suspected. Urine culture is not helpful.

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19
Q

A patient reports severe back pain located in the lumbar spine. To evaluate whether the patient has axial pain or radicular pain, which assessment is necessary?

a. Asking the patient to perform the Valsalva maneuver
b. Assessing reflexes and asking about tingling or numbness
c. Determining whether the pain is present with prolonged sitting
d. Noting whether pain is mitigated with frequent position shifts

A

a. Asking the patient to perform the Valsalva maneuver

axial pain = dull and acing

ridicular pain caused by things that can cause the spinal nerve root to be pinched which causes searing pain down the nerve roots

Valsava maneuver determine if pain is caused by radicular or axial

Associated neurological signs are present with radicular pain and include numbness, tingling, weakness, and reflex changes.

The other symptoms occur with both axial and radicular pain.

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20
Q

A patient has an acute onset of lower back pain associated with lifting heavy objects at work. A physical examination reveals no loss of lower extremity function or neurological symptoms. What is the initial intervention for this patient?

a. Magnetic resonance imaging (MRI) to evaluate soft tissue involvement
b. Plain radiographs to evaluate the extent of the injury
c. Traction therapy to minimize complications
d. Treatment with a nonsteroidal anti-inflammatory drug (NSAID)

A

d. Treatment with a nonsteroidal anti-inflammatory drug (NSAID)

NSAIDs are appropriate as first-line treatment in patients without potential complications.

Radiologic studies are performed if improvement does not occur in 4 to 6 weeks.

Traction may be used for patients with radicular symptoms to help resolve neurological deficits, although systematic review of research has not clearly identified a benefit to this therapy

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21
Q

A patient has recurrent lumbar pain which is sometimes severe. The patient reports that prescription of nonsteroidal anti-inflammatory drugs (NSAIDs) is no longer effective for pain relief. What will the provider recommend?

a. Adjunctive treatment with physical therapy
b. Beginning treatment with opioid analgesics
c. Complementary and alternative therapies
d. Referral to an interventional spine physician

A

d. Referral to an interventional spine physician

Patients with recurrent or chronic lower back pain may benefit from lumbar epidural corticosteroid injection performed by an interventional spine physician.

Physical therapy is often used for ACUTE injury if no improvement in 4 to 6 weeks.

Opioid analgesics are not usually effective.

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22
Q

An adult patient who has been taking high-dose corticosteroids reports a dull, aching pain in the groin and presents with a limp. What condition does the provider suspect, based on this history?

a. Avascular necrosis of the femoral head
b. Infectious arthritis of the hip
c. Osteoarthritis of the hip
d. Slipped capital femoral epiphysis (SCFE)

A

a. Avascular necrosis of the femoral head

Avascular necrosis has the symptoms listed above and is common among patients who have been taking corticosteroids. Infectious arthritis will typically be accompanied by fever and intense pain. Osteoarthritis causes progressively worsening pain with activity and improvement with rest. SCFE is common in adolescents.

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23
Q

A patient with chronic hip pain cannot take nonsteroidal anti-inflammatory drugs (NSAIDs) and tells the provider that acetaminophen is minimally helpful. What might the provider recommend initially to improve pain relief?

a. A fentanyl patch
b. Capsaicin
c. Glucosamine
d. Lidocaine patches

A

b. Capsaicin

Topical capsaicin has been shown to provide short-term pain relief and has fewer side effects than oral agents. It is an appropriate initial therapy. Fentanyl is a narcotic analgesic and should be reserved for more severe pain. Glucosamine and lidocaine may be helpful for some patients.

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24
Q

A high school soccer player sustains a knee injury when kicked on the lateral side of the knee by another player. The provider notes significant swelling of the knee, with pain at the joint line on the medial aspect of the knee. What will the provider do to treat this injury?

a. Instruct about RICE management and follow up in 1 week
b. Refer for a same-day orthopedic consultation
c. Schedule a magnetic resonance imaging (MRI) exam
d. Splint the knee and refer for orthopedic consultation in 1 to 2 weeks

A

b. Refer for a same-day orthopedic consultation

bases off of symptoms: sounds like either Meniscus or MCL.

This patient has an injury caused by a traumatic event associated with swelling and should have a same-day orthopedic consultation.

Simple sprains may be managed with RICE. MRI may be ordered by the orthopedist.

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25
Q

Which maneuver during a physical examination is used to assess the anterior cruciate ligament (ACL)?

a. Anterior drawer test
b. Posterior drawer test
c. Valgus stress on knee joint
d. Varus stress on knee joint

A

a. Anterior drawer test

The anterior drawer test, in which the examiner pulls the tibia forward while the knee is flexed, is used to assess anterior cruciate ligament laxity.

The posterior drawer test is used to determine posterior cruciate ligament laxity.

The valgus stress test assesses the medial collateral ligament (MCL) laxity

The varus stress test assesses the lateral collateral ligament (LCL) laxity.

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26
Q

A previously healthy patient reports a sensation of one knee locking or feeling like it will give way when descending stairs. The patient has no recollection of injury to the knee and denies pain. What is the most likely treatment for this disorder?

a. Conservative management with RICE and activity modification
b. Immediate referral to an orthopedic surgeon for possible repair
c. Intraarticular injections of corticosteroids three times yearly
d. Restricting participation in sports and strenuous workouts indefinitely

A

a. Conservative management with RICE and activity modification

Test= McMurry’s test
This patient has symptoms consistent with chronic degenerative meniscal injury and is without pain or significant disability. Conservative management is indicated.

Immediate referral is indicated for severe pain or disability. Intra-articular injections of corticosteroids are used for patients with concomitant osteoarthritis.

Patients should be encouraged to continue sports and exercise to improve overall muscle tone and minimize disability.

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27
Q

The primary care provider is assessing a 45-year-old postmenopausal woman who has a family history of osteoporosis. Which test will be most useful to screen for this disease in this patient?

a. Biochemical markers of bone resorption and bone formation
b. Bone densitometry of the hip and posteroanterior lumbar spine
c. Plain radiographs of the hips and lumbar and thoracic spine
d. Serum calcium and serum 25-hydroxyvitamin D

A

b. Bone densitometry of the hip and posteroanterior lumbar spine

Postmenopausal women are candidates for bone densitometry to assess for osteopenia and osteoporosis.
SX fractures with no history of trauma

decrease levels of Estrogen decreases bone remolding

osteoporosis- osteoclast (destroys old bone and repairs then increases ca in blood) activity rate exceeds that of osteoblast (bone rebuilders)

Biochemical markers are generally ordered by specialists; their role in primary care is uncertain.

Plain radiographs are used to determine fracture.

Serum calcium and vitamin D levels are useful in the general population as a preventive measure.

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28
Q

A patient is diagnosed with osteoporosis. What is the recommended treatment once the diagnosis is made?

a. Bisphosphonate therapy
b. Calcium and vitamin D
c. Estrogen replacement
d. Yoga and weight-bearing exercises

A

a. Bisphosphonate therapy

Bisphosphonates are FDA-approved treatment for osteoporosis and will help IMPROVE bone density and reduce the risk of fractures. PREVENT FRactures
**take biphoshates on an empty stomach with 6-8 ounzes of water
Calcium and vitamin D may help prevent osteoporosis but must be taken from an early age.

Estrogen replacement is used to PREVENT bone loss.

Yoga and exercise help with balance and muscle strength to help prevent falls.

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29
Q

A patient has bone pain and laboratory testing reveals an elevated serum alkaline phosphatase (SAP). Which test can help distinguish Paget’s from malignant bone disease?

a. Bone densitometry
b. Bone marrow biopsy
c. Bone radiograph
d. Bone scan

A

c. Bone radiograph

A plain bone radiograph will show changes pathognomonic of Paget’s disease. The other tests are not necessary.

Paget disease is a disease that disrupts the replacement of old bone tissue

30
Q

A patient comes to a provider with reports of unilateral arm pain and weakness with mild neck pain. The provider notes that the patient prefers holding the affected arm crossed in front of the throat. A history reveals a recent onset of sexual dysfunction. What does the provider suspect based on this history?

a. Axial neck pain
b. Cervical myelopathy
c. Diabetic neuropathy
d. Facet joint pain

A

b. Cervical myelopathy

Patients with neurological symptoms have radicular neck pain, which is usually greater in one arm and involves neurological findings.
Patients with concurrent lower extremity findings may have cervical myelopathy and should be evaluated immediately.

Axial neck pain does not involve neurological findings.

Diabetic neuropathy typically does not include neck pain. Facet joint pain is a cause of axial neck pain, associated with injuries and headaches.

31
Q

A provider suspects degenerative disk disease in a patient with chronic neck pain. Which diagnostic test will be performed?

a. Computerized tomography (CT)
b. Magnetic resonance imaging (MRI)
c. Plain radiograph
d. Radionuclide bone scintigraphy

A

b. Magnetic resonance imaging (MRI)

MRI is usually performed to diagnose degenerative disk disease.

CT testing is used to identify bone and degenerative changes, but the exposure to radiation is high. Plain radiographs are used to identify fractures or when trauma or cancer is present. Radionuclide bone scintigraphy is used for osteomyelitis, metastatic disease, or occult fracture.

32
Q

A patient has chronic radicular neck pain that no longer responds to over-the-counter NSAIDs and physical therapy measures and reports having difficulty sleeping. Which medication will the provider order?

a. A skeletal muscle relaxant
b. A tricyclic antidepressant
c. An opioid analgesic
d. Gabapentin

A

d. Gabapentin

Gabapentin is useful for central pain syndromes and radiculopathy and can help to restore sleep.

Skeletal muscle relaxants are useful for muscle spasms.

A tricyclic antidepressant is useful for some chronic neck pain, although gabapentin is more specific to this patient’s symptoms.

Opioid analgesics should be used cautiously.

33
Q

A 50-year-old woman reports pain in one knee upon awakening each morning that goes away later in the morning. A knee radiograph is negative for pathology and serum inflammatory markers are normal. What will the provider tell this patient?

a. A magnetic resonance imaging study is necessary for diagnosis
b. That the lack of findings indicates no disease process
c. To take acetaminophen 1 gram three times daily for pain
d. To use a cyclooxygenase 2-selective NSAIDs to reduce inflammation

A

c. To take acetaminophen 1 gram three times daily for pain

Symptoms: insidious pain or stiffness in one of more joints more common in knees, hips (weight bearing) fingers, toes, hands) worse in morning
relieved by rest* more common in women

WILL HAVE NO SERUM INFLAM MARKERS

Acetaminophen is the mainstay for initial treatment of osteoarthritis.
Radiologic findings are often negative in the early stages of the disease.

There are no serologic markers for OA.

A COX-2-selective inhibitor has cardiovascular side effects and should not be used unless necessary. These agents are used more for pain than for inflammation.

34
Q

A patient who has osteoarthritis in the carpometacarpal joints of both thumbs asks about corticosteroid injections to treat symptoms. What will the provider tell this patient about this therapy?

a. Corticosteroid therapy reduces inflammation and improves joint mobility
b. Injections may be administered as needed up to 6 times per year
c. Intraarticular injections provide significant pain relief for 3 to 4 months
d. This treatment may cause a temporary increase in pain, warmth, and redness

A

d. This treatment may cause a temporary increase in pain, warmth, and redness

SX worse in am but get better or get worse with repeated activity but relieve with rest

Intraarticular injections of corticosteroids are helpful in decreasing pain, but may cause a transient increase in pain, warmth, and redness. This therapy does not improve inflammation and joint mobility.

Injections are not recommended more than 3 to 4 times per year. The
duration of pain relief is variable.

35
Q

A 45-year-old patient has mild osteoarthritis in both knees and asks about nonpharmacologic

therapies. What will the provider recommend?
a. Aerobic exercise
b. Glucosamine with chondroitin
c. Therapeutic magnets or copper bracelets
d. Using a cane or walker

A

a. Aerobic exercise
Osteoarthristis is degenerative joint disease, affects thumbs phalangeas (Heberden nodes)

Tylenol first line therapy
Aerobic exercise helps with cardiovascular conditioning and weight reduction as well as improved range of motion, decreased pain, and strengthening of supporting structures.

Randomized controlled studies have failed to demonstrate significant pain relief with glucosamine.

Therapeutic magnets and copper have not been proven to be effective.

A young patient with mild symptoms will not need assistive devices and should focus on conditioning.

36
Q

50-year-old patient with diabetes mellitus has a low-grade fever and pain on one foot. The provider notes erythema and swelling at the site along with several superficial skin ulcers without necrosis and suspects osteomyelitis. Which type of diagnostic study will the provider order?

a. Biopsy of bone or debridement cultures
b. Blood cultures and serologic markers of inflammation
c. Magnetic resonance imaging of the foot
d. Plain radiograph of the foot

A

d. Plain radiograph of the foot

A patient with diabetic foot infection suspected of having osteomyelitis should have a plain radiograph to identify bony abnormality or soft tissue changes.

MRI may be performed if more specific evaluation is needed or if abscess is suspected. Blood cultures are not diagnostic of osteomyelitis.

Biopsy and debridement cultures increase the risk of further infection if poor healing at the site occurs

37
Q

A 3-year-old child has marked pain in one leg localized to the upper tibia with refusal to bear weight. The child has a high fever and a toxic appearance. Which type of osteomyelitis is most likely?

a. Chronic osteomyelitis
b. Hematogenous osteomyelitis
c. Osteomyelitis from a contiguous focus
d. Peripheral vascular disease osteomyelitis

A

b. Hematogenous osteomyelitis

Young children are more likely to have hematogenous osteomyelitis, especially with acute symptoms.

Chronic osteomyelitis is more common with underlying diseases such as diabetes.

Contiguous focus osteomyelitis occurs when organisms are introduced from a puncture
wound, foreign body, or adjoining soft tissue infection. Peripheral vascular causes are more common in chronically ill patients.

38
Q

A patient has osteomyelitis related to vascular insufficiency. Which initial consultation is necessary?

a. Infectious disease consultation
b. Neurosurgical consultation
c. Surgical consultation
d. Wound care specialist consultation

A

c. Surgical consultation

Because patients with vascular insufficiency who develop osteomyelitis may need
debridement or draining of lesions, a surgical consult is necessary.

Infectious disease consults are obtained for patients with resistant organisms or complex wounds.
Neurosurgical consults are needed for patients with epidural abscess.

Wound care consults are needed for patients with progressive or chronic wounds.

39
Q

A 45-year-old patient reports a recent onset of unilateral shoulder pain which is described as diffuse and is associated with weakness of the shoulder but no loss of passive range of motion. What does the provider suspect as the cause of these symptoms?

a. Acromioclavicular joint disease
b. Cervical radicular pain
c. Glenohumeral arthritis
d. Rotator cuff injury

A

d. Rotator cuff injury

Rotator cuff injury is usually characterized by diffuse pain, weakness of the joint, but no change in range of motion.
Test: Empty can test: rotator cuff associated with stability of the shoulder

Acromioclavicular joint disease is associated with anterior-superior shoulder pain.

Glenohumeral arthritis has similar symptoms, but with loss of range of motion.

Cervical radicular pain is characterized by pain distal to the elbow.

40
Q

An examiner is evaluating a patient who reports unilateral shoulder pain and notes limited active and passive range of motion in the affected shoulder along with erythema and bulging on the anterior shoulder. What diagnosis is likely with this presentation?

a. Acromioclavicular joint disease
b. Adhesive capsulitis
c. Inflammatory bursitis
d. Rotator cuff tear

A

c. Inflammatory bursitis

Both bursitis and adhesive capsulitis will present with decreased active and passive range of motion, but patients with inflammatory bursitis will exhibit erythema and bulging of the anterior shoulder.

Acromioclavicular joint disease does not cause erythema or bulging of the joint.

41
Q

A patient reports a deep ache in one shoulder and the provider suspects tendonitis secondary to repetitive activity. To determine whether the pain is caused by impingement on the acromion, the provider will ask the patient to

a. abduct the arm.
b. adduct the arm.
c. internally rotate the shoulder.
d. shrug the shoulders.

A

a. abduct the arm.

If pain is caused by impingement on the acromion, the patient will reflexively shrug when asked to abduct the arm to reduce the pain.

Adduction of the arm does not elicit this response.

The shrug elicited is reflexive and not intentional.

Internal rotation may be performed to evaluate generalized muscle weakness.

42
Q

A soccer player is brought to the emergency department after twisting an ankle during a game. An examination of the affected joint reveals ecchymosis and edema of the ankle and limited joint laxity along with pain on weight-bearing, although movement with pain is intact. Which grade sprain is likely?

a. Grade I
b. Grade II
c. Grade III
d. Grade IV

A

b. Grade II

This patient probably has a grade II sprain, which involves incomplete tear of a ligament with some functional impairment, ecchymosis, and pain with weight-bearing.

A grade I sprain causes only pain and edema.

A grade III sprain is a full or complete tear of the ligament with loss of ligament integrity.

A grade IV sprain results in severe weakness with loss of function.

43
Q

A school-age child falls off a swing and fractures the humerus close to the elbow joint. What is the most important assessment for this patient to evaluate possible complications of this injury?

a. Evaluation of pain with extension
b. Palpation for joint laxity
c. Salter-Harris classification
d. The presence of a spiral fracture

A

c. Salter-Harris classification

Salter-Harris classification identifies the degree of epiphyseal, or growth plate involvement and is important to evaluate in children and adolescents, since damage to the growth plate can result in shortening of the long bone.

The other assessments are part of the exam but have less importance than assessment of growth plate involvement.

44
Q

An emergency department provider is giving instructions for rest, ice, compression, and elevation (RICE) treatment in a patient with a sprain. What is included in teaching about this home care? (Select all that apply.)

a. An elastic bandage is enough for compression.
b. Apply ice packs for 20 minutes three times daily.
c. Proximal joints should be elevated higher than distal joints.
d. The injured extremity should be raised above the level of the heart.
e. Place a cloth between the ice pack and the skin.

A

a. An elastic bandage is enough for compression.
d. The injured extremity should be raised above the level of the heart.
e. Place a cloth between the ice pack and the skin.

There is good evidence supporting use of an economical elastic bandage for support and compression. Elevation of the extremity above the level of the heart after the injury helps to reduce the edema and thereby decrease initial pain. If using an ice pack, a cloth should be placed between the ice pack and the skin to prevent cold burn. Ice packs should be applied at 20-minute intervals, allowing the skin to return to normal temperature before each application. Distal joints should be higher than proximal joints.

45
Q

A patient reports elbow pain and the examiner elicits pain with resisted wrist flexion, forearm pronation, and passive wrist extension on the affected side. What is a likely cause of this pain?

a. Lateral epicondylitis
b. Medial collateral ligament instability
c. Medial epicondylitis
d. Ulnar neuritis

A

c. Medial epicondylitis

Medial epicondylitis will produce pain as described above. Lateral epicondylitis may result in pain with passive wrist flexion and active wrist extension.

46
Q

A patient has chronic elbow pain associated with arthritis. What is included in management of this condition? (Select all that apply.)

a. Avoidance of certain activities
b. Balanced rest and exercise
c. Long-term NSAIDs
d. Occupational therapy
e. Splinting of the elbow

A

a. Avoidance of certain activities
b. Balanced rest and exercise
d. Occupational therapy

Patients with arthritis may be managed by avoiding pain-causing activities, a program of balanced rest and exercise, and occupational therapy to improve function. NSAIDs are used for short periods. Splinting is not recommended.

47
Q

A 40-year-old woman reports pain at the thumb base in one hand radiating to the distal radius. The provider learns that the woman knits for a hobby and is able to elicit the pain by asking the patient to pour water from a pitcher. Which condition is suspected in this patient?

a. Carpal tunnel syndrome
b. Palmar fibrosis
c. De Quervain’s Tenosynovitis
d. Trigger finger

A

c. De Quervain’s Tenosynovitis

De Quervain’s tenosynovitis causes pain as described and occurs more in women between 30 and 59 years who engage in activities requiring excessive repetitive motions, such as knitting. Carpal tunnel syndrome presents with intermittent wrist pain, numbness, and tingling radiating from the palm to the thumb, index finger, middle finger, and medial aspect of the ring finger.
*Finkelstein test
Palmar fibrosis causes contractures, usually of the ring finger.

Trigger finger causes nodules in tendons that catch on the finger pulley and impede movement.

48
Q

A patient reports numbness and weakness of the wrist with pain focuses on the radial aspect of the joint. During physical examination, what will the examiner do to help diagnose this condition?

a. Applying press to the focus area
b. Flexing the thumb while placing a finger on the metacarpophalangeal joint
c. Passively extending the thumb and observe for puckering of the skin
d. Placing the thumb on the palm while deviating the hand toward the ulna

A

a. Applying press to the focus area

Applying pressure to the volar or radial aspect of the wrist will elicit pain in patients with a ganglion cyst which has symptoms described above.

Flexing the thumb while the examiner places a finger on the metacarpophalangeal joint will elicit a pop when the digit is extended in patients with trigger finger.

Puckering of the skin occurs with palmar fibrosis. Placing the patient’s thumb on the palm while deviating the hand toward the ulna will elicit pain in patients with tenosynovitis.

49
Q

A patient has symptoms of carpal tunnel syndrome. Which diagnostic tests will help confirm this disorder? (Select all that apply.)

a. Anti-nuclear antibody (ANA)
b. Electromyography
c. Erythrocyte sedimentation rate (ESR)
d. Nerve conduction studies
e. Plain radiographs

A

b. Electromyography
d. Nerve conduction studies

While diagnosis may be made on history and physical findings, electromyography and nerve conduction studies can be helpful to confirm or exclude carpal tunnel syndrome. ANA and ESR testing are useful when rheumatoid arthritis is suspected. Plain radiographs are not useful.

50
Q

A 40-year-old woman reports pain at the thumb base in one hand radiating to the distal radius. The provider learns that the woman knits for a hobby and is able to elicit the pain by asking the patient to pour water from a pitcher. Which condition is suspected in this patient?

a. Carpal tunnel syndrome
b. Palmar fibrosis
c. De Quervain’s Tenosynovitis
d. Trigger finger

A

De Quervain’s tenosynovitis
-painful inflam of Dorsal aspect of wrist
- Pain with ulnar deviation (pouring something)
-pain located at thumb base
** most common in women age 30-40 d/t position of wrist when holding a baby
SX localized n/t, weakness
TEST= Finkelstein test

causes pain as described and occurs more in women between 30 and 59 years who engage in activities requiring excessive repetitive motions, such as knitting.

Carpal tunnel syndrome presents with intermittent wrist pain, numbness, and tingling radiating from the palm to the thumb, index finger, middle finger, and medial aspect of the ring finger.

Palmar fibrosis causes contractures, usually of the ring finger. Trigger finger causes nodules in tendons that catch on the finger pulley and impede movement

51
Q

A patient reports numbness and weakness of the wrist with pain focuses on the radial aspect of the joint. During physical examination, what will the examiner do to help diagnose this condition?

a. Applying press to the focus area
b. Flexing the thumb while placing a finger on the metacarpophalangeal joint
c. Passively extending the thumb and observe for puckering of the skin
d. Placing the thumb on the palm while deviating the hand toward the ulna

A

a. Applying press to the focus area

Applying pressure to the volar or radial aspect of the wrist will elicit pain in patients with a ganglion cyst which has symptoms described above.

ganglion cyst = fluid like sacs that can appear and disappear, occur around joints, smooth and rubbery as well as transilluminates

Flexing the thumb while the examiner places a finger on the metacarpophalangeal joint will elicit a pop when the digit is extended in patients with trigger finger.

Puckering of the skin occurs with palmar fibrosis.

Placing the patient’s thumb on the palm while deviating the hand toward the ulna will elicit pain in patients with tenosynovitis. (finkelstein test like in De Quervain)

52
Q

A patient has symptoms of carpal tunnel syndrome. Which diagnostic tests will help confirm this disorder? (Select all that apply.)

a. Anti-nuclear antibody (ANA)
b. Electromyography
c. Erythrocyte sedimentation rate (ESR)
d. Nerve conduction studies
e. Plain radiographs

A

b. Electromyography
d. Nerve conduction studies

While diagnosis may be made on history and physical findings, electromyography and nerve conduction studies can be helpful to confirm or exclude carpal tunnel syndrome.

***ANA and ESR testing are useful when rheumatoid arthritis is suspected.

Plain radiographs are not useful.

53
Q

A patient reports elbow pain and the examiner elicits pain with resisted wrist flexion, forearm pronation, and passive wrist extension on the affected side. What is a likely cause of this pain?

a. Lateral epicondylitis
b. Medial collateral ligament instability
c. Medial epicondylitis
d. Ulnar neuritis

A

c. Medial epicondylitis

Medial epicondylitis will produce pain as described above. Lateral epicondylitis may result in pain with passive wrist flexion and active wrist extension.

54
Q

A patient has chronic elbow pain associated with arthritis. What is included in management of this condition? (Select all that apply.)

a. Avoidance of certain activities
b. Balanced rest and exercise
c. Long-term NSAIDs
d. Occupational therapy
e. Splinting of the elbow

A

a. Avoidance of certain activities
b. Balanced rest and exercise
d. Occupational therapy

Patients with arthritis may be managed by avoiding pain-causing activities, a program of balanced rest and exercise, and occupational therapy to improve function. NSAIDs are used for short periods. Splinting is not recommended.

55
Q

A patient is diagnosed with polymyalgia rheumatica (PMR) with giant cell arteritis. Which dose of prednisolone will be given initially?

a. 15 mg daily
b. 20 mg daily
c. 30 mg daily
d. 60 mg daily

A

d. 60 mg daily

Although the usual starting dose to treat PMR is 15 to 20 mg daily, a higher dose of 60 mg daily is used when there is evidence of concomitant giant cell arteritis.

PMR-treatable, chronic inflam condition of unknown cause
SX diffuse, dull, aching and stiffness in am

PMR= inflammatory arthritis that is not errosisve and ASYMMETRIC, highly responsive to corticosteroids.
most common in shoulder, neck and pelvis

Treated with steroid (prednisolone) low dose over 1-2 years unless patient has symptoms of Giant cell arthritis

Giant cell arthritis = systemic vasculitis that affect medium blood vessels

Sx will include new onset HA in TEMPORAL region = most common site
can radiate to jaw and have tenderness to scalp, and tongue probs can lead to stroke, vision problems=emergency

treated with 60mg predinisolone with taper total course then low dose daily for 1-2 years

RA=auto immune arthritis with symmetric joint degeneration accompanied by systemic symptoms, will have deformaties
most common in hands wrists and elbows

56
Q

A patient who is taking prednisolone 20 mg daily to treat polymyalgia rheumatica reports blurred vision. What will the provider do?

a. Discontinue the medication
b. Increase the prednisolone dose to 60 mg daily
c. Prescribe NSAIDs to treat the inflammation
d. Refer to a rheumatologist immediately

A

d. Refer to a rheumatologist immediately

Sudden vision loss, diplopia, and other visual disturbances may indicate giant cell arteritis
(GCA) and requires immediate referral to rheumatology.

Giant cell arthritis = systemic vasculitis that affect medium blood vessels

Sx will include new onset HA in TEMPORAL region = most common site
can radiate to jaw and have tenderness to scalp, and tongue probs can lead to stroke

treated with 60mg predinisolone with taper total course then low dose daily for 1-2 years

Sudden vision loss, diplopia, and other visual disturbances may indicate giant cell arteritis
(GCA) and requires immediate referral to rheumatology. The primary provider should not change the medication regimen without a consult.change the medication regimen without a consult.

57
Q

a. Antinuclear antibodies
b. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)
c. Liver function tests (LFTs)
d. Protein electrophoresis
e. Serum calcitonin

A

b. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)
c. Liver function tests (LFTs
d. Protein electrophoresis

ESR, CRP, and protein electrophoresis are included in the initial diagnostic workup when polymyalgia rheumatica is suspected. And CBC 50% may have systemic symptoms like RA must rule out other causes

ANA testing is not specific for this disorder. Will be negative along with Rheum factor Serum calcitonin is not indicated.

58
Q

A provider performs a nail fold capillaroscopy on a patient who reports marked color changes of both hands with cold exposure and notes tortuous and dilated capillary loops. This finding is consistent with what condition?

a. Polymyositis
b. Primary Raynaud’s phenomena
c. Scleroderma
d. Secondary Raynaud’s phenomena

A

d. Secondary Raynaud’s phenomena

Microvascular abnormalities like tortuous of dilated capillary loops are observed in secondary Raynaud’s phenomena and capillaroscopy is used to differentiate primary from secondary Raynaud’s.

These findings are not present with polymyositis or scleroderma.

59
Q

A patient has secondary Raynaud’s phenomena with severe digital ischemia. Which treatment is indicated for this patient?

a. Ginkgo biloba
b. Intravenous prostaglandin E1
c. Oral nifedipine
d. Sildenafil as needed

A

b. Intravenous prostaglandin E1

Intravenous prostaglandin E1 is reserved for patients with secondary Raynaud’s phenomenon who have severe digital ischemia.

Ginkgo biloba is associated with adverse effects and has not been shown to be effective.
MILD CASE
Nifedipine is used to prevent vasospasm in milder cases.

Sildenafil may be used as a vasodilator in milder cases.

60
Q

A patient has swelling and tenderness in the small joints of both hands and reports several weeks of malaise and fatigue. A rheumatoid factor (RF) test is negative. What will the primary care provider do next?

a. Begin treatment with a biologic disease-modifying anti-rheumatic (DMARD) drug
b. Order radiographic tests, a CBC, and acute-phase reactant levels
c. Reassure the patient that the likelihood of rheumatoid arthritis is low
d. Refer the patient to an orthopedic specialist for evaluation and treatment

A

b. Order radiographic tests, a CBC, and acute-phase reactant levels

The patient has signs of rheumatoid arthritis (RA); THE RF TEST MAY BE NEGATIVE INITIALLY but will become positive in 70% to 80% of patients. The provider’s next step is to order tests to confirm the diagnosis and to provide a baseline to monitor disease progress and response to treatment.

DMARDs may be ordered when the disease is confirmed = treatment like METHOTREXATE

The PCP may treat in consultation with a rheumatologist (MUST HAPPEN TO CONFIRM DIAGNOSIS AND INITIATE TREATMENT) who will order medications and will refer the patient for physical therapy, occupational therapy, and psychotherapy.

RA= systemic autoimmune disorder, erosive arthritis characaterized with SYMMETRICAL INFLAMMATORY POLYARTHRITIS

  • joints in hands.fingers first then wrists, elbows
  • will have deformities (swan nodes)
  • *****WILL HAVE SYSTEMIC SX-fever, chillsm malaise, anemia

Labs: ESR, CRP = elevated
anticyclic citrullinated peptide

COMPLICATIONS; uveitis (eye inflam) with vision probs, reddness = IMMEDIATE REFERRAL TO OPTHO,
-lymphoma

61
Q

A patient is diagnosed with rheumatoid arthritis (RA) after a review of systems, confirmatory lab tests, and synovial fluid analysis. What will the provider order initially to treat this patient?

a. Disease-modifying anti- rheumatic (DMARDs) drugs
b. Long-term glucocorticoid therapy
c. Non-pharmacological treatments
d. Nonsteroidal anti-inflammatory drugs (NSAIDs)

A

a. Disease-modifying anti- rheumatic (DMARDs) drugs

Treatment with DMARDs should be initiated as soon as the diagnosis of RA is established to achieve disease modification. = Methotrexate
Long-term glucocorticoid therapy is not recommended because of adverse effects.

**NSAIDs are not first-line drugs, INCREASE RISKS OF CARDIAC AND RENAL COMPLICATIONS **

NSAIDs are used as adjunctive and not first-line therapy.

62
Q

Which are symptoms of rheumatoid arthritis (RA) that distinguish it from osteoarthritis (OA)? (Select all that apply.)

a. Extra-articular inflammatory signs
b. History of injury to affected joints
c. Morning stiffness of at least 1 hour
d. Symmetric tender, swollen joints
e. Unilateral joint involvement

A

a. Extra-articular inflammatory signs
c. Morning stiffness of at least 1 hour
d. Symmetric tender, swollen joints

The clinical presentation of RA includes extra-articular symptoms (fever, malaise, anemia), morning stiffness lasting at least 1 hour, and SYMMETRIC BILAT JOINT INVOLVEMENT

OA often has a history of previous injury and is usually ASYMMETRIC AND MAY BE UNILATERAL JOINT INVOLVEMENT

63
Q

A patient is diagnosed with ankylosing spondylitis and begins taking a COX-2 inhibitor with minimal pain and inflammation relief. What will the provider order initially to manage this patient’s symptoms?

a. A trial of sulfasalazine and methotrexate
b. Biologic anti-tumor necrosis factor agents
c. Changing to a COX-1 inhibitor medication
d. Corticosteroid injections every 3 months

A

c. Changing to a COX-1 inhibitor medication

NSAIDs have been shown to reduce pain and stiffness and reduce progression of structural damage if administered continuously. Patients should try at least two NSAIDs before other medications are attempted. Sulfasalazine and methotrexate have not been shown to be significantly effective for axial disease. Biologic anti-tumor necrosis factor medications are given only after failure of two NSAIDs. Corticosteroid injections are not indicated.

64
Q

A patient is treated for a urinary tract infection and, 3 weeks later, presents with pain and swelling of one knee and in one hand, along with inflammation in both eyes. What will the provider suspect as the cause of these symptoms?

a. Ankylosing spondylitis
b. Infectious arthritis
c. Psoriatic arthritis
d. Reactive arthritis

A

d. Reactive arthritis

Reactive arthritis can cause arthritis, urethritis, and inflammation of the eyes 1 to 6 weeks after a prior infection.

Ankylosing spondylitis generally presents with lower back inflammation.

Psoriatic arthritis is associated with psoriasis. Reactive arthritis is not related to infection in the involved joints.

65
Q

A patient reports a history of recurrent lower back pain for 6 months. The patient describes the pain as a deep ache and stiffness that is worse upon awakening and improves after walking. Which findings will the examiner elicit to help make a clinical diagnosis of ankylosing spondylitis? (Select all that apply.)

a. Assessment of the degree of lumbar lordosis
b. Evaluation of lateral thoracic spine flexion
c. Measurement of chest expansion
d. Noting the degree of cervical kyphosis
e. Observation for scapular asymmetry

A

a. Assessment of the degree of lumbar lordosis
b. Evaluation of lateral thoracic spine flexion
c. Measurement of chest expansion

Examination of the spine will show loss of the normal lumbar lordosis, decreased thoracic spine flexion, and diminished chest expansion. Cervical kyphosis is not assessed. Scapular asymmetry evaluates for scoliosis.

66
Q

A patient with systemic lupus erythematosus (SLE) develops end-stage renal disease. Because of the underlying SLE, what treatment is recommended for this patient?

a. Dialysis only
b. Immunosuppressant therapy
c. Kidney transplantation
d. Palliative care

A

c. Kidney transplantation

Patients with SLE who develop renal failure may require dialysis and then kidney transplantation; most who undergo transplant do relatively well because of the immunosuppression given to prevent graft rejection. Immunosuppressant therapy is given for graft rejection and does not treat end-stage renal failure. Palliative care is not the only option for this patient.

67
Q

Which laboratory tests may help distinguish systemic lupus erythematosus (SLE) from other systemic rheumatologic disorders?

a. Antinuclear antibody titer
b. C-reactive protein
c. Rheumatoid factor
d. Serum complement levels

A

d. Serum complement levels

With SLE, complement levels may decrease because of the activation and deposition of immune complexes in tissues. The other tests are non-specific tests for inflammation and rheumatologic disorders.

SLE= chronic multisystem autoimmune disease that is more common in women, disease may cause rashes (butterfly and discoid rash

TYPICALLY will have protein in urine

68
Q

A patient with systemic lupus erythematosus (SLE) has frequent symptoms and has been taking prednisone for each episode. The provider plans to start hydroxychloroquine and the patient asks why this medication is necessary. What will the provider tell this patient about this medication?

a. It is effective in reducing disease flares and for tapering steroids.
b. It is given in conjunction with steroids to improve outcomes.
c. It lowers blood pressure and decreases the risk for renal disease.
d. It prevents the need for bisphosphonate therapy.

A

a. It is effective in reducing disease flares and for tapering steroids.

SLE treated with NSAIDS, steroids, antimalaria, immune modulators

Hydroxychloroquine is effective in managing musculoskeletal, cutaneous, and serosal manifestations of SLE and allows tapering of steroids and reduces disease flares.

Cyclophosphamide is given with prednisone to improve renal outcomes.

Hydroxychloroquine is not given for effects on blood pressure and kidneys.

Calcium and vitamin D are given to prevent the need for bisphosphonates.

69
Q

Which is a distinctive finding in patients who are diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA)?

a. Erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)
b. Hepatitis B virus (HBV) surface antigen
c. Increased eosinophils
d. Positive antinuclear antibodies (ANA)

A

c. Increased eosinophils

Unique to EGPA are large numbers of circulating and tissue-based eosinophils.

ESR and CRP are non-specific markers of inflammation HBV surface antigen is often present in polyarteritis nodosa.

ANA levels are present in many autoimmune diseases.

70
Q

A child presenting with a high fever, bilateral conjunctivitis, and a desquamating rash is presumed to have a vasculitic disease. What is the likely treatment for this child?

a. Antibiotic therapy for 10 to 14 days
b. Aspirin (ASA) and intravenous immunoglobulin (IVIG)
c. High-dose prednisolone therapy
d. Immunosuppressant medications

A

b. Aspirin (ASA) and intravenous immunoglobulin (IVIG)

This patient has symptoms of Kawasaki disease. Because of the risk for coronary aneurysms and death, ASA and IVIG are indicated. Antibiotics, prednisolone, and immunosuppressants are not useful.

71
Q

A patient has a palpable purpura rash. This finding is most consistent with what condition?

a. Small-vessel vasculitis
b. Medium-vessel vasculitis
c. Large-vessel vasculitis
d. Central-vessel vasculitis

A

a. Small-vessel vasculitis

A palpable purpura rash is the most helpful physical examination finding of a small-vessel vasculitis.