Module 3 Flashcards
1
Q
Whats the difference in jobs of hemoglobin and myoglobin?
A
Hemoglobin: Transports O2.
Myoglobin: Stores O2 in muscle.
2
Q
How many subunits do hemoglobin and myoglobin have?
A
Hemoglobin: 4
Myoglobin: 1
3
Q
Whats the purpose of subunits?
A
They bind to Heme groups which bind to iron which bind to oxygen.
4
Q
What are 5 characteristics of hemoglobin in the lung?
A
High affinity for O2 Relaxed (readily awaiting to pick up O2) Higher pH Lower CO2 Low H+
5
Q
What are 5 characteristics of hemoglobin in the muscle?
A
Lower affinity for O2 Tense (readily awaiting to drop off O2) Muscles tense up* Lower pH Higher CO2 Lots of H+
6
Q
What shop is hemoglobin when it is in its T or R state?
A
T : Domed (deoxygenated).
R: Flat/Planar (oxygenated).
7
Q
How does pH affect the Bohr effect?
A
The higher the pH the stronger the affinity of oxygen
8
Q
What does 2,3 BPG do?
A
It binds to hemoglobin and promotes the T state.
