Module 2D Respiratory Drugs Flashcards
Contraindications for antihistamine
Sever liver diseases, narrow-angle glaucoma, urinary retention
Mode of adm for CROMOLYN AND NEDOCROMIL
Inhalation
For:
○ Prophylactic treatment of bronchial asthma
○ Not to be used for acute asthma attack
Antiinflammatory effect and suppresses the release of histamine
CROMOLYN AND NEDOCROMIL
Nursing interventions for leukotriene receptor antagonist
Assess herbal meds intake
Prophylactic and maintenance for chronic asthma; causes decrease in bronchoconstriction
LEUKOTRIENE RECEPTOR ANTAGONIST
○ Zafirlukast (Accolate)
○ Montelukast (Singulair)
Xanthines when taken with Beta-adrenergic agonist (terbutaline) causes
synergistic effect cardiac
dysrhythmias
Xanthines when taken with __________cause decrease effects
Barbiturate and carbamazepine
Xanthines when taken with Beta-blockers, cimetidine (Tagamet), propranolol (Inderal) and erythromycin causes
decreased metabolism rate or increase the
half-life of theophylline
Caution xanthines when px have hx of
○ Seizure
○ Cardiac, renal, or liver disorders
Causes bronchodilation; for COPD and asthma;
XANTHINES
○ Aminophylline (Somophyllin)
○ Theophylline (Theo-Dur)
○ Oxtriphylline (Choledyl)
Anticholinergic drugs (respi) have potential increase fluorocarbon toxicity when used with
other inhalation bronchodilators having a fluorocarbon propellant
Used For COPD
ANTICHOLINERGIC
Examples of this drug include ○ Epinephrine (adrenaline) ○ Isoproterenol (Isuprel) ○ Terbutaline (Brethine) ○ Metaproterenol (Alupent) ○ Albuterol (Proventil, Ventolin)
BETA2 - ADRENERGIC AGONIST
beta2 adrenergic agonists decrease with
beta blockers (-olol)
Facilitates smooth muscle relaxation and inhibits mast cell
degranulation
CAMP- CYCLIC ADENOSINE MONOPHOSPHATE
Nursing interventions for bronchodilators
avoid food containing xanthine (cola, coffee, tea)
An autoimmune disorder wherein antibodies destroy
communication between nerves and muscles
Myasthenia gravis
Symptoms include:
Dyspnea, excess mucus secretion
● Airway obstruction, bronchospasm
● Permanent irreversible damage to the lung tissue
COPD
LOWER RESPIRATORY TRACT disorders causes
difficulty breathing
Increase /liquefy respiratory secretions to aid in the clearing of
airway for patients who are coughing thick, tenacious secretions
MUCOLYTICS
● Acetylcysteine (Mucomyst)
● Dornase alfa (Pulmozyne)
For: ○ Non-productive cough ○ Low viscosity of tenacious secretion Act on the cough-control center in the medulla to suppress the cough reflex
ANTITUSSIVES Dextromethorphan hydrobromide (benylin)
Nursing interventions for INTRANASAL GLUCOCORTICOIDS (STEROIDS)
Clear nasal passages before administration
Do not use INTRANASAL GLUCOCORTICOIDS (STEROIDS) if
there is a presence of untreated acute
infection (mucus)
Used to treat allergic rhinitis; May be used alone or in combination with H1 antihistamines; decrease inflammatory activity in the
bronchial wall, inhibit constriction of airway
INTRANASAL GLUCOCORTICOIDS (STEROIDS)