Module 2: Chapter 6: Life span: Children Flashcards
The textbook defines a pediatric patient as what
less than 16 years of age and under 50kg
what % of drugs regularly prescribed to children in the US have never been labeled for use in any pediatric population
75
is it now considered ethical or unethical to exclude children from drug studies
unethical
what must nurses be aware of until all drugs have been tested and labeled for sue in children?
off-label use that will occur
what are most pediatric doses based on
the childs weight in kilograms
what is used to determine the dosage in pediatric patients if a child dose is not specified
can be determined from the adult dose based on the body SA of the child
what can be used to determine a childs surface area to determine dosing
nomogram
True or false a drugs mechanism of action is the same in all individuals regardless of age
true
true of false in very young children immature organ systmes have less than optimal functioning
true
true or false a childs age, growth and maturation can affect how the body absorbs, distributes, metabolizes and excretes a drug
true
what can a nurse do regarding adverse and therapeutic effects
maximize therapeutic effects and minimize adverse effects
what can be done with dosages to account for immature or impaired body systems in neonates and infants
lowered
what can have an effect on pediatric drug absorption
age disease process dosage form route foods and drugs present in the childs body
is an infants GI tract more or less acidic than an adults
less acidic
compared to adults do infants have a higher or lower body SA
higher
what are fat and water levels like in children compared to adults
children have higher concentrations of water
lower concentrations of fat
does a neonates liver produce more or less plasma proteins then adults
fewer
what is the difference in the blood brain barrier in children compared to adults
at birth the blood-brain barrier is not full developed
immaturity of the nonatal and infant liver results in _____ or ___ metabolism of many drugs
decreased or incomplete
a child with an immature or compromised liver fn is at risk for what
drug toxicity
why are drugs that require oxidation for metabolism frequently more rapidly metabolized in children than adults
because children ahve a faster resting respiratory rate
immaturity of the nonatal and infant liver results in ____ or _____ metabolism of many drugs
decreased or incomplete
in children with impaired renal fn, drug dosages should be _____ to acheive and maintain therapeutic drug levels
alterered
the neonate, especially the preterm infant, has immature kindeys so renal excretion of the drug is
slow
true or false: many drugs excreted through the bilary tree into the intestinal tract
false: few drugs
is biliary drug flow increased or decreased during the first few days of life
increased
are most drugs prescribed to children prescribed for their labeled use or off labeled use
off labeled
are drugs that are dangerous for children labelled as such?
obviously