Module 2 - Cells And Tissues Flashcards
It is the smallest unit of life.
Cells
Cells that connect body parts, form linings or transport gases.
Epithelial Cells, Fibroblasts, Erythrocytes
Cells that move organs and body parts.
Skeletal muscle cell, Smooth muscle cells
Cell that stores nutrients.
Fat cell
Cell that fights disease.
Macrophage
Cell that gathers information and controls body functions.
Nerve cell
Cell of reproduction.
Sperm
A selectively permeable barrier and a phospholipid bilayer with protein molecules plugged in as a fluid mosaic.
Plasma Membrane
An intracellular fluid packed
with organelles.
Cytoplasm
The organelle that controls
cellular activities.
Nucleus
It includes interstitial fluids, blood plasma, cerebrospinal fluid (CSF).
ECF (extracellular fluid)
The substances that aid in digestion (gastric fluids) or act as lubricants (saliva).
Cellular secretions
Most abundant material, jellylike substance composed of proteins and polysaccharides.
Extracellular matrix (ECM)
It forms the fabric of the membrane (phospholipid +
cholesterol).
Membrane Lipids
It allows the membrane to communicate with its
environment, responsible for specialized membrane function.
Membrane Proteins
It includes glycoproteins and glycolipids.
Glycocalyx (carbohydrate rich area) provides identity molecules for specific
biologicals markers.
Membrane Carbohydrates
It allows neighboring cells to adhere and to communicate,
inhibit or aid in allowing movement of molecules between cells.
Cell Junctions
Form basic structure of the membrane.
Phospholipids
Stiffens the membrane and further decreases the water solubility of the membrane.
Cholesterol
It determines what functions the membrane can perform.
Proteins
They act as identity molecules.
Carbohydrates
Encloses the cell, separating the cytoplasm from the extracellular fluid. (Functions of the Plasma Membrane)
Physical Barrier
Determines which substances enters or exit
the cell. (Functions of the Plasma Membrane)
Selective Permeability
Plasma membrane proteins interact with specific chemical messengers and relay messages to the cell interior. (Functions of the Plasma Membrane)
Communication
Cell surface carbohydrates allow cells to recognize each other. (Functions of the Plasma Membrane)
Cell Recognition
Face the water inside and outside the cell. (includes phosphate group)
Polar Hydrophilic head
Hide from the water. (fatty acids)
Nonpolar Hydrophobic tail
Type of protein that is embedded in the lipid bilayer.
Integral proteins
Type of protein that is anchored to the membrane or to the other proteins.
Peripheral proteins
What are the membrane proteins functions?
Transport, receptors for signal transduction, Enzymatic activity, Cell - cell recognition, Attachment to the cytoskeleton and extracellular matrix (ECM), Cell - cell joining.
Impermeable junctions that form continuous seals around the cell.
Tight junctions
Anchoring junctions that help keep cells from tearing apart.
Desmosomes
Communicating junctions that allow ions and small molecules to pass from cell to cell.
Gap junctions
Diffuse directly through the lipid bilayer (usually small nonpolar molecules that
readily dissolve in lipids).
Simple Diffusion
Either through a) binding to
carrier proteins or 2) through water filled channel
proteins.
Facilitated Diffusion
Diffusion of a solvent through a membrane.
Osmosis
Diffusion via protein carrier specific for one chemical; binding of solute causes transport protein to change shape.
Carrier - mediated facilitated diffusion
Diffusion through a channel protein; mostly ions selected on basis of size and charge.
Channel - mediated facilitated diffusion
Refers to the ability of a solution to change the shape of cells by
altering the cells; internal water volume.
Tonicity
Have the same concentrations of nonpenetrating solutes as those
found in the cells, retain shape, exhibit no net loss or gain of water.
Isotonic
Higher concentration of nonpenetrating solutes than seen in the
cell, lose water, shrivel or crenate.
Hypertonic
More dilute than cells, cells plump up or lyse.
Hypotonic
Cells retain their normal size and shape in this solution (same solute/water concentration as inside cells; water moves in and out).
Isotonic solutions
Cells lose water by osmosis and shrink in this solution (contains a higher concentration of non-penetrating solutes than are present inside the cells).
Hypertonic solutions
Cells take on water by osmosis until they become bloated and burst (lyse) in this solution (contains a lower concentration of non-penetrating solutes than are present inside the cells).
Hypotonic solutions
Requires transport proteins that combine specifically and reversibly with the transported substances
and move solutes uphill, against a concentration gradient using energy.
Active Transport
The transport of substances against a concentration (or electrochemical) gardient.
Primary active transport
Cotransport (coupled transport) of two solutes across the membrane.
Secondary active transport
A large external particle (proteins, bacteria, dead cell debris) is surrounded by a pseudopod (false foot) and becomes enclosed in a vesicle (phagosome).
Phagocytosis
Plasma membrane sinks beneath an external fluid droplet containing small solutes. Membrane edges fuse, forming a fluid - filled vesicle.
Pinocytosis (fluid - phase endocytosis)
External substance binds to membrane receptors and is a selective endocytosis and transcytosis.
Receptor - mediated endocytosis
Vesicles pinch off from organelles and travel to other organelles to deliver their cargo.
Vesicular trafficking
Secretion or ejection of substances from a cell.
Exocytosis
Also termed as voltage, electrical potential energy resulting from the separation of oppositely charged particles.
Membrane Potential
Ranging from (-)50 – (-)90 mV.
Resting Membrane Potential
According to Ren, Roberts and Shi (2011), these molecules are cell surface proteins that mediate the interaction between cells, or between cells and the extracellular matrix (ECM).
Cell Adhesion Molecules (CAMs)
Diverse group of integral proteins that serve as binding sites.
Plasma Membrane Receptors