Module 2 Flashcards
What are the five major function of the skeletal system
Support, protection, assistance with movement, blood cell production, storage
Cartilage:
- made of matrix.
- avascular.
- no nerves.
Cartilage growth:
2 ways:
- Appositional growth (cartilage is added to outside of the existing cartilage)
- Interstitial growth (chondrocytes within the matrix divide and add more matrix between the chondrocytes)
cartilage types
hyaline cartilage:
-collagen fibres are small and evenly dispersed in the matrix therefore matrix appears transparent and is firm but flexible. Chondrocytes are found in lacunae.
-allows the growth of long bones.
-contain chondroblasts that produce the matrix.
Fibrocartilage:
-more collagen bundles than hyaline and are arranged in thick bundles.
Elastic cartilage:
-Matrix collagen similar to hyaline but also contains elastic fibres.
What are the components of bone tissue (ie the matrix) and how do they relate to its properties?
Organic - Collagen fibres and proteoglycans -> stops bone from being too brittle.
Inorganic - Hydroxyapatite -> stops bone from being too bendable.
Name the three main bone cell types and state their function
Osteoblasts - Bone forming cells; produce the chemicals and structures that make up the matrix (lay down the matrix).
Osteoclasts - Bone destroying cells; breaks down the matrix.
Osteocytes - Maintain the matrix.
What is the role of collagen in bone tissue?
Bone strength -> stops it from being brittle.
Distinguish between compact and spongy (cancellous) bone?
Spongy bone:
• Appears porous and contains columns of bone called trabeculae. It usually surrounded by a sleeve of compact bone.
• provides strength and support without the greater weight of compact bone.
• In the interior of the bones of the skull, vertebrae, sternum and pelvis; in the ends of the long bones.
Compact bone:
• very organised.
has a hard bong matrix with many osteocytes.
basic unit: osteon/harvesian system.
• great strength and support; prevents breaks and punctures.
located in the outer portions of all bones and the shafts of long bone.
Classify bones according to their shape, give examples.
- long: upper and lower limbs e.g. femur, tibia.
- short: carpals and tarsals.
- flat: ribs, sternum, skull, scapulae.
- irregular: vertebrae, facial.
Describe the general structure of a long bone.
- diaphysis.
- epiphysis.
- epiphyseal plate.
- epiphyseal line.
- medullary cavity.
Describe in detail the arrangement of bone tissue in compact bone.
Layers of bone (lamellae) form around the central canal form the osteon. Osteocytes sit in the spaces between the lamellae (called lacunae). Periosteum is a dense, irregular CT sheath surrounding the bone. Endosteum is the thin membrane lining the medullary cavity.
What is the embryonic precursor tissue and cell of bone?
Mesoderm and mesenchymal tissue.
How does bone ossify and how is this different for flat and long bones?
- intramembranous - flat
- endochondral – long
Intramembranous: Bone forms directly from mesenchyme. Takes place within connective tissue membranes. Flat bones.
Endochondral: Takes places within a cartilage template. Bone forms from mesenchyme producing a hyaline cartilage model first which is replaced by bone tissue. Long bones.
Distinguish epiphyseal lines and plates on an X-ray and explain what the presence of each will tell about the growth of bone.
- epiphyseal plate is a band of cartilage left between primary and secondary ossification centres
- the plate includes rows of young cartilage cells undergoing mitosis and new cartilage cells are being produced
- as bone ages the cartilage cells are progressively converted to bone
- when all the cartilage cells become bone an epiphyseal line is formed. growth in length stops
What are the components of the axial and appendicular skeleton?
Axial:
- 80 bones.
- bones of the head and trunk; ossicles (inner ear), skull, hyoid bone, rib cage and the vertebral column.
Appendicular:
- 126 bones.
- consists of the bones and cartilages that support the appendages.
