Module 2 Flashcards
A chronic neurobiologic disease whose development is influenced by genetic psychosocial,& environmental factors (same as psychological dependence)
Addiction
Binds to receptor & causes a response
Agonist
Substance that bind to a receptor & cause a partial response that is not as strong as that caused by an agonist( aka partial agonist)
Agonists-antagonist
What occurs when a given pain drug no longer effectively controls a patient’s pain despite the administration of the highest safe dosage
Analgesic ceiling effect
Medications that relieve pain without causing loss of consciousness(aka painkillers)
Analgesics
A drug that binds to a receptor& prevents(blocks) a response
Anagonist
Pain that occurs between doses of pain medication
Breakthrough pain
Pain resulting from any disorder that causes central nervous system damage
Central pain
Sudden onset of pain, usually subsides when treated & typically occurs over less than a 6 wk period
Acute pain
Persistent or recurring pain that is often difficult to treat. Includes any pain lasting longer that 3-6months, pain lasting longer than 1month after healing of an acute injury or pain that accompanies a nonhealing tissue injury.
Chronic pain
The most well-described theory of pain transmission & pain relief. It uses a gate model to explain how impulses from damaged tissues are sensed in the brain
Gate Theory
Pain that results from a disturbance of function or pathologic change in a nerve
Neuropathic pain
Processing of pain signals in the brain that gives rise to the feeling of pain
Nociception
A subclass of sensory nerves(A and C fibers) that transmit pain signals to the central nervous system from other body parts
Nociceptors
Analgesics that are not classified as opioids
Nonopioid analgesics
A large chemically diverse group of drugs that are analgesics & also posses anitinflammatory & antipyretic activity but are not corticosteroids
Nonsteroidal antiinflammatory drugs(NSAIDS)
Synthetic drugs that bind to opiate receptors to relieve pain
Opioid analgesics
Describes patients who are receiving opioid analgesics for the first time & who therefore are not accustomed to their effects
Opioid naive
A normal physiologic condition that results from long-term opioid use, in which large doses of opioids are required to maintain the same level of analgesia & in which abrupt discontinuation of the drug results in withdrawal symptoms
Opioid tolerence
Unpleasant sensory & emotional experience associated with actual or potential tissue damage
Pain
The level of stimulus that results in the sensation of pain
Pain tolerance
Pain that originates from skeletal muscles, ligaments, or joints
Somatic pain
The general term for a state in which repetitive exposure to a given drug, over time, induces changes in drug receptors that reduce the drug’s effects
Tolorence
An international organization of health care professionals that studies & responds to health needs & trends worldwide
World Health Organization(WHO)
Hyperuricemia; build up of uric acid crystals in tissue and joints
Gout
A localized protective response stimulated by injure to tissues that serves to destroy, dilute, or wall of both the injurious agent and the injured tissue
Inflammation
A large and chemically diverse group of drugs that possess analgesic, antiinflammatory and antipyretic activity
Nonsteroidal antiinflammatory drugs(NSAIDs)
The syndrome of salicylate toxicity, insluding syptoms such as tinnitus, nausea & vomiting
Salicylism
