Module 2

Question 1

A chronic neurobiologic disease whose development is influenced by genetic psychosocial,& environmental factors (same as psychological dependence)

Answer 1

Addiction

Question 2

Binds to receptor & causes a response

Answer 2

Agonist

Question 3

Substance that bind to a receptor & cause a partial response that is not as strong as that caused by an agonist( aka partial agonist)

Answer 3

Agonists-antagonist

Question 4

What occurs when a given pain drug no longer effectively controls a patient’s pain despite the administration of the highest safe dosage

Answer 4

Analgesic ceiling effect

Question 5

Medications that relieve pain without causing loss of consciousness(aka painkillers)

Answer 5

Analgesics

Question 6

A drug that binds to a receptor& prevents(blocks) a response

Answer 6

Anagonist

Question 7

Pain that occurs between doses of pain medication

Answer 7

Breakthrough pain

Question 8

Pain resulting from any disorder that causes central nervous system damage

Answer 8

Central pain

Question 9

Sudden onset of pain, usually subsides when treated & typically occurs over less than a 6 wk period

Answer 9

Acute pain

Question 10

Persistent or recurring pain that is often difficult to treat. Includes any pain lasting longer that 3-6months, pain lasting longer than 1month after healing of an acute injury or pain that accompanies a nonhealing tissue injury.

Answer 10

Chronic pain

Question 11

The most well-described theory of pain transmission & pain relief. It uses a gate model to explain how impulses from damaged tissues are sensed in the brain

Answer 11

Gate Theory

Question 12

Pain that results from a disturbance of function or pathologic change in a nerve

Answer 12

Neuropathic pain

Question 13

Processing of pain signals in the brain that gives rise to the feeling of pain

Answer 13

Nociception

Question 14

A subclass of sensory nerves(A and C fibers) that transmit pain signals to the central nervous system from other body parts

Answer 14

Nociceptors

Question 15

Analgesics that are not classified as opioids

Answer 15

Nonopioid analgesics

Question 16

A large chemically diverse group of drugs that are analgesics & also posses anitinflammatory & antipyretic activity but are not corticosteroids

Answer 16

Nonsteroidal antiinflammatory drugs(NSAIDS)

Question 17

Synthetic drugs that bind to opiate receptors to relieve pain

Answer 17

Opioid analgesics

Question 18

Describes patients who are receiving opioid analgesics for the first time & who therefore are not accustomed to their effects

Answer 18

Opioid naive

Question 19

A normal physiologic condition that results from long-term opioid use, in which large doses of opioids are required to maintain the same level of analgesia & in which abrupt discontinuation of the drug results in withdrawal symptoms

Answer 19

Opioid tolerence

Question 20

Unpleasant sensory & emotional experience associated with actual or potential tissue damage

Answer 20

Pain

Question 21

The level of stimulus that results in the sensation of pain

Answer 21

Pain tolerance

Question 22

Pain that originates from skeletal muscles, ligaments, or joints

Answer 22

Somatic pain

Question 23

The general term for a state in which repetitive exposure to a given drug, over time, induces changes in drug receptors that reduce the drug’s effects

Answer 23

Tolorence

Question 24

An international organization of health care professionals that studies & responds to health needs & trends worldwide

Answer 24

World Health Organization(WHO)

Question 25

Hyperuricemia; build up of uric acid crystals in tissue and joints

Answer 25

Gout

Question 26

A localized protective response stimulated by injure to tissues that serves to destroy, dilute, or wall of both the injurious agent and the injured tissue

Answer 26

Inflammation

Question 27

A large and chemically diverse group of drugs that possess analgesic, antiinflammatory and antipyretic activity

Answer 27

Nonsteroidal antiinflammatory drugs(NSAIDs)

Question 28

The syndrome of salicylate toxicity, insluding syptoms such as tinnitus, nausea & vomiting

Answer 28

Salicylism