Module 2 Flashcards
4 components of a physical exam for respiratory assessment
- inspection
- palpation
- percussion
- auscultation
Normal findings for respiratory assessment (observe, inspect, palpate, percussion, auscultation)
-observe pattern of breathing (RR 12-14rr/min) and rhythm (regular with a sigh every 90 breaths or so), depth of breathing/tidal volume, relative time spent inspiration and expiration (ratio 2:3)
-inspect for extrapulmonary signs of pulmonary disease –> use what you find to perform more detailed exam
-palpate: 1. trachea at suprasternal notch 2. posterior chest wall (gauge fremitus/transmission through lungs of vibrations of spoken words) 3. anterior chest wall (assess cardiac impulse)
-percussion: identifies dull areas or hyperresonant areas
-auscultation of lung sounds
Extrapulmonary signs (4)
-digital clubbing (lung abscess, empyema, bronchiectasis, CF, idiopathic pulmonary fibrosis, AV malformations; late presentation: concomitant lung cx
-Cyanosis: blue or bluish-gray discoloration of skin & mm due to inc amounts of unsaturated HgB in capillary blood (anemia: may prevent cyanosis from appearing; polycythemia: cyanosis in mild hypoxemia) –> cyanosis not reliable indicator of hypoxemia = get arterial PO2 or HgB saturation measured
-Inc CVP: indirectly measures pulmonary HTN (major complication of chronic lung dx); impaired ventricular function, pericardial effusion, or restriction, valvular heart dx, COPD
-BLE edema: indirectly measures pulmonary HTN (major complication of chronic lung dx) w/ chronic lung disease = RV failure
Kussmaul respirations
rapid LARGE VOLUME breathing = intense stimulation of respiratory center r/t metabolic ACIDosis
Cheyne-stokes respirations
RHYTHMIC, waxing/waning of rate and RV, regular periods of APNEA (seen in end-stage LV failure, neurological dx, sleeping at high altitude
What is wheezing a powerful indicator for?
obstructive lung disease (asthma, COPD)
Does rhonchi clear after cough?
YES
Risk factors for CAP
older age, hx of etoh/tobacco, asthma/COPD/immunocompromised
Timing of CAP (in relation to the hospital)
Occurs prior to admission (to the hospital) or within 48 hours of admission
Sx of CAP
-Acute or subacute onset of fever (low in elderly) (FEVER)
-Cough (w/ or w/o sputum) (COUGH)
-Dyspnea/tachypnea (sensitive sign in elderly) (DYSPNEA)
-Mental status change (elderly) (MENTAL)
-Rales, bronchial breath sounds or inspiratory crackles (SOUNDS)
-Parenchymal opacity on x-ray (X-RAY)
What bacteria is primarily responsible for CAP?
S pneumoniae
Viruses that cause CAP?
RSV, Influenza A/B, adenovirus/parainfluenza virus, human metapneumonvirus
Is diagnostic testing required/recommended for outpatient management of CAP? Why?
NO (only hospitalized patients). Empiric abx is almost always effective in this population w/o need for dx tests
What 3 widely available rapid point of care tests are used to ID causative organism in CAP?
- Sputum gram stain
- Urinary antigen tests (S pneumonia, legionella species)
- COVID RT-PCR/Rapid Test
Why should you obtain a rapid flu test when dx CAP?
Because positive flu tests reduce unnecessary abx use
What imaging is required to establish a dx of CAP?
Pulmonary opacity on chest x-ray
CAP - Can a CXR identify causative organism or distinguish bacterial from viral pneumonia?
NO
CAP - If CXR shows SIGNIFICANT pleural fluid collections, what should the NP do?
REFER (thoracentesis)
CAP - If CXR shows cavitary opacities, what should the NP do?
ISOLATE and REFER to ED - to rule out TB
Recommended outpatient abx choice for CAP patient who was previously healthy with no recent (90 day) antibiotic use?
Amoxicillin
Doxycycline (100mgBIDx5days)
**do not use fluroquinolones in ambulatory pt w/o comorbidities or recent abx use - RISK OF TENDON RUPTURE
Recommended outpatient abx choice for CAP patient with previous risk of drug resistance (abx<90 days, >65yrs old, comorbid illness (COPD/CHF/DM/Cx/Chronic renal/liver), alcoholism, immunosuppression, exposed to child in daycare?
-Macrolide or doxy PLUS oral beta-lactam (Augmentin) OR
-Oral respiratory fluoroquinolone (moxifloxacin, gemifloxacin, levofloxiacin)
*if abx <90days, choose new one from different class
CAP - what is the typical abx tx for adults?
5 days (continue abx until pt is afebrile for 40-72hrs)
-cough, fatigue may last up to 4 weeks
Prevention techniques against CAP?
PPSV23, PCV13 (PCV15), influenza, COVID19
CURB-65
Screening tool for CAP
Assess 5 predictors to calculate a 30 day predicted mortality rate
-Confusion
-Urea: BUN >7mmol/L (20mg/L)
-Respiratory rate: >30/min
-BP: systolic <90, diastolic <60
-Age: >65 years old
0 = outpt tx is probably safe
1-2 = admit to hospital for care
3-4 = URGENT REFERRAL! Admit to ICU.
PSI
Screening tool for CAP
Pneumonia severity index
-Age, gender, nursing home status, comorbid conditions, physical exam, and labs (including blood pH) to determine hospitalization
Anaerobic pneumonia risk factors
hx of predisposition of aspiration (nocturnal asthma, chemical pneumonitis, bronchiectasis, AMS (drugs/ETOH), seizures, general anesthesia, CNS disease, neuromuscular dx, ET tube/NG tube, poor dentition)
Does anaerobic pneumonia have insidious or gradual onset?
Insidious
Symptoms of anaerobic pneumonia
insidious onset of fever, weight loss, malaise, COUGH WITH FOUL-SMELLING SPUTUM = anaerobic
What diagnostic test is used for anaerobic pneumonia?
Chest X-ray
Treatment for anaerobic pneumonia?
IV clindamycin or Augmentin q12 hr; or Pen G and Flagyl. Treat until resolution on X-ray.
What is a major determining factor regarding the lung zone affected at time of aspiration for anaerobic pneumonia?
Body position
What does an air-filled cavity in lung suggest?
Abscess
What does the presence of multiple areas of cavitation within an area of consolidation lead the NP to suspect?
Necrotizing pneumonia
The presence of purulent pleural fluid accompanying either lung abscess or necrotizing pneumonia would indicate what complication (anaerobic pneumonia)?
Empyema
Treatment for anaerobic pneumonia
1st line: IV clindamycin q8hr OR Augmentin q12hr
Alternative: Amox or PCN G + metronidazole (flagyl)
Length of treatment for:
-Anaerobic pneumonia
-Lung abscess
-Empyema
-until CXR improves (month or more)
-until CXR resolution of abscess cavity is demonstrated
-REFER (must have tube thoracostomy)
Key symptoms of pleuritis
localized pain, sharp, fleeting - worse with coughing, sneezing, deep breaths or movement; diaphragmatic involvement = referred ipsilateral shoulder pain
Cause of pleuritis in healthy, young adults?
viral resp infection or pneumonia; simple rib fracture
Treatment for pleuritis
Treat underlying dx
-Pain: analgesics/NSAIDs (indomethacin, etc.)
-Control cough: codeine or other opioid; promitozine cough syrup
What would you do if pleural effusion, pleural thickening, or air in pleural space observed?
REFER!!
Definition of Pleuritis
Inflammation of pleural lining
Definition of Pleural effusion
collection of fluid in pleural space
Risk factors associated with pleural effusion
chest pain + pleuritis, trauma, or infection
Common findings related to pleural effusion
dyspnea (large effusions –> dullness to percussion and decreased/absent breath sounds over effusion); CXR shows pleural effusion; diagnostic findings on thoracentesis
Sx associated with pleural effusion?
Unilateral chest pain, worse with inspiration or deep breathing; dullness to percussion; dec/absent breath sounds where effusion located
Pulmonary infiltrates - how do you diagnose in immunocompromised patient?
Sputum culture!
If no clinically apparent cause for pleural effusion, how is it diagnosed?
Thoracentesis
Symptoms of spontaneous pneumothorax
Acute UNILATERAL chest pain, dyspnea
UNILATERAL chest expansion
Decreased tactile fremitus
Hyperresonance
Types of spontaneous pneumothorax
Primary
Secondary
Signs and symptoms of small pneumothorax
mild tachycardia
Signs and symptoms of large pneumothorax
diminished breath sounds, decreased tactile fremitus, decreased movement of chest
Lab findings related to pneumothorax
-ABG: hypoxemia, resp alkalosis
-EKG: left-sided primary pneumothorax = QRS axis and precordial T wave changes - can appear like MI
Treatment for pneumothorax (primary, secondary, small, large)
*treat cough and pain (serial CXR q 24 hrs)
-Small, stable spontaneous pneumothorax: observation alone may be appropriate
-Large, progressive pneumothorax: needle decompression (16g needle) –> place chest tube (small-bore tube) attached to one-way Hemlich valve (provides protection against development of tension pneumothorax); may permit observation from home
Treatment for tension pneumothorax
chest tube under water seal drainage with suction (removed after air leaks subsides)
What causes risk of reoccurrence of pneumothorax?
Smoking, high altitudes, flying in unpressurized aircraft, scuba diving
What coexists with obstructive sleep apnea?
Obesity-hypoventilation syndrome (blunted ventilatory drive and increased mechanical load imposed upon the chest by obesity)
Patients with pulmonary venous thromboembolism have a history of what?
DVT
Symptoms of pulmonary venous thromboembolism
-dyspnea
-chest pain worse with inspiration
-cough
-hemoptysis
-syncope
-tachypnea
-widened alveolar-arterial PO2 difference (hypoxemia with right-to-left shunting)
How to diagnose PE (what diagnostic tests)?
-d-dimer (increased)
-CT pulmonary angiography (abnormalities/VQ Scan-for those who cannot tolerate contrast dye)
-EKG (ST or T wave change, tachycardia), then REFER
Substances that could embolize to lung circulation causing PE?
-Air
-Amniotic fluid
-Fat
-Foreign bodies
-Parasite eggs
-Septic emboli
-Tumor cells
Risk factors for thrombus formation
-Venous stasis
-Injury to vessel wall
-Hypercoagulability
-Immobility
-Inc CVP ((Dec CO states, pregnancy)
-Inherited dx (factor V Leiden)
Labs/Diagnostic tests for suspected PE?
ECG
ABG
d-dimer
CXR
CT angiogram
Venous ultrasound (rule out proximal DVT)
Profound hypoxia with normal CXR in absence of lung disease - what are you suspicious for?
PE
What is the clinical prediction tool for determining patient probability of PE?
Wells Clinical Prediction rule (modified Wells score of 4 or mess who meet all PERC criteria ORDER a d-dimer)
What is a form of secondary prevention (med) for PE?
Heparin anticoagulation therapy (standard regimen) followed by 6 month PO warfarin (another effective drug is LMWH - recommended for patients’ with cancer)
What is the appropriate duration of therapy for patients with PE?
No standard
What is a major complication from treatment of PE? What should you be monitoring?
Hemorrhage; INR (target INR = 2.0-3.0)
What medication therapy is instituted for an established PE?
Rt-PA
Alteplase: thrombolytic therapy (high risk pts) –> choose if needs lifesaving tx
ABSOLUTE CONTRAINDICATIONS FOR THROMBOLYTIC THERAPY
active internal bleeding
stroke w/i past 2 months
MAJOR CONTRAINDICATIONS TO THROMBOLYTIC THERAPY
uncontrolled HTN
Surgery/trauma within past 6 weeks
Symptoms of RSV
-low-grade fever
-tachypnea
-wheezing
-apnea
-increased mucous secretion
Physiologic sx of RSV
hyperinflated lungs, decreased gas exchange, increased WOB
At what ages is RSV mortality highest?
<5yrs; >65yrs
Risk factors for RSV
prematurity
early RSV bronchiolitis in kids + family hx of asthma –> persistent airway reactivity in life
Wells Score - for patients with Modified Wells <equal 4 who meet ALL of the following criteria, PE is excluded, follow off anticoagulation, and search for alternative dx. List criteria (8)
- Age <50yrs
- HR <100bpm
- Oxyhemoglobin saturation on room air >equal 95%
- No prior hx of venous thromboembolism
- No recent (w/i 4 weeks) trauma or surgery requiring hospitalization
- No presenting hemoptysis
- No estrogen therapy
- No unilateral leg swelling
How is seasonal influenza spread?
Droplet
Symptoms of seasonal influenza in relation to:
-unvaccinated adults
-kids with type B
-elderly
-abrupt onset of fever, chills, HA, malaise, myalgias, runny/stuffy nose, sore throat, hoarseness, cough, substernal soreness
-GI complaints
-Lassitude, confusion, w/o fever or respiratory sx
How long is the incubation period for seasonal influenza?
1-4 days
When to suspect secondary bacterial infection during seasonal influenza illness
Recurrent fever or persistent fever >4 days w/ productive cough and WBC >10,000
-most common = pneumococcal pneumonia; staph pneumonia = most serious
Treatment for seasonal influenza
Tamiflu
75mg by mouth BID 5 days
-most effective if given w/i 2 days of sx start
Relenza: inhalation powder (oral inhalation). Used for influenza A and B
-contraindicated with asthma