Module 2 Flashcards
Life cycle of Malaria
Mosquito injeccts sporozites 2.) Merozoites infect RBCs 3.) Picked up by misquito 4.) transmitted to human
Is Sickle Cell reciessive or dominiate?
Reciessive
What can cause sickle cell?
Ischemia
O2 decrease
1 sickle cell allel
Heterozygous
Little effect
2 sickle cell alleles
Homozygous
Severly impacted
Benifts of having the Sickle Cell allel
The increase in oxygen triggers sickel cell response in RBC causing malaria infected cells to be taken out of the blood cells quickly therefore limiteding pathogens ability to grow and take hold
If you have No copies of HbS you are likely to contract
Malaria
If you have 1 copy of HbS you are likely to contract
Malaria resistance
If you have 2 copies of HbS you are likely to contract
Sickle Cell Anemia
Alzheimers Disease
Degenerative Brain disease
What allele is affected?
Apolipoprotein (ApoE4)
What does the Apolipoprotein (ApoE4) predict?
Genetic prediction of Alzheimer’s Disease
Raises the risk of Alzheimer’s by 4xs compared to non-carriers
What do most parasites prefer to eat?
Lipids
Fats