Module 2 Flashcards

1
Q

does have iron

A

ferroprotoporphyrin

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2
Q

don’t have iron

A

protoporphyrin 9

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3
Q

2 identical pairs

A

globin chains

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4
Q

alpha and zeta chains : ___ amino acids

A

141

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5
Q

beta and gamma chains : ___ amino acids

A

146

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6
Q

unknown number of amino acids

A

theta

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7
Q

4 heme group attached to 4 globin chains

A

tetrameric molecule

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8
Q

forms cleft-pocket for hem

A

quaternary structure

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9
Q

uroporphyrinogen iii to coproporphyrinogen iii by the action of

A

uroporphyrinogen decarboxylase

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10
Q

alpha and zeta in short arm of

A

chromosome 16

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11
Q

gamma, beta, delta, epsilon in short arm of

A

chromosome 11

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12
Q

came from the common myeloid progenitor lineage

A

erythrocyte

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13
Q

days proliferation & maturation of precursors

A

6-7

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14
Q

days reticulocyte maturation

A

2-3

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15
Q

3 phases of an erythrocyte’s life

A

-Erythrocyte production
-Bone marrow release to the circulation
-Destruction or cell death

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16
Q

number RBCs produced from a single Pronormoblast

A

8-32

17
Q

Production of ___reticulocytes from each pronormoblast

A

16

18
Q

3 phases of development pathway in RBC

A

-Ribosome synthesis
-Hgb accumulation
-Ejection of nucleus

19
Q

Single, most useful test to check or analyze if there’s anemia.

A

reticulocyte test

20
Q

chromatin is distributed irregularly throughout the cytoplasm

A

karyorrhexis

21
Q

basophilic nuclear remnants or clusters of DNA in the circulating erythrocytes.

A

Howell-jolly bodies

22
Q

It has a detectable hemoglobin synthesis

A

prorubriblast

23
Q

this is the last stage that undergo mitosis

A

rubricyte

24
Q

Totality of all stages of erythrocytes, including precursor cells in the bone marrow and mature cells in the peripheral blood within vascular areas of specific organs

A

erythron

25
Q

important in hemoglobin production

A

iron

26
Q

Destruction > production

A

anemia

27
Q

Production > destruction

A

erythrocytosis

28
Q

Enhance the Heme production
Increase the numbers of the first forming unit erythropoiesis and the colony forming unit erythropoiesis colony

A

prostaglandins

29
Q

Imitation of lights that occur as a result of a certain chemical reaction.

A

CHEMILUMINESCENCE

30
Q

Happens when there is over stimulation of the normal bone marrow leading to overproduction of RBCs

A

secondary polycythemia

31
Q

Artificial erythropoietin that were injected in the body usually to the athletes, to boost the blood to increase oxygen in order to bring more oxygen in the system

A

blood doping

32
Q

Balance of the production and destruction of the RBCs

A

Erythrokinetics

33
Q

Negatively charged or also known

A

zeta potential

34
Q

Hydrophobic nonpolar acyl tails - (Tails)
Inner layer

A

-Phosphatidylserine
-Phosphatidylethanolamine

35
Q

Hydrophobic nonpolar acyl tails - (Tails) Outer layer

A

Phosphatidylcholine
Sphingomyelin

36
Q

Change is the position of the phospholipids within the cell membrane.

A

floppases

37
Q

Inner to Outer
Translocation of the phospholipids between the 2 monolayers of lipid bilayer of a cell membrane from inner to outer

A

scramblases

38
Q

Predominant skeletal protein

A

spectrin