Module 12.1 - Nutritional Considerations Flashcards

1
Q

What are some characteristics of malnutrition?

A
  • Independent risk factor for patient morbidity and mortality in hospitalized patients
  • Prevalence as high as 40% among critically ill adults due to lack of proper evaluation and failure to optimize nutritional support early in hospitalization
  • Associated with increased healthcare costs
  • No standard methods of screening or diagnostic criteria
  • Inflammation/infection has been identified as risk factor for malnutrition due to a marked increase in metabolism, leading to greater energy (caloric) requirements and loss of lean body mass
  • Independent of type and severity of disease, duration of hospitalization impacts the risk of malnutrition; longer the stay = increase risk
  • Laboratory markers are NOT reliable by themselves, should be used in conjunction with a thorough physical exam.
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2
Q

What are 6 laboratory measures of malnutrition?

A

1. Serum albumin

  • Produced by the liver
  • Half-life 14-20 days (synthesis requires amino acids and adequate liver function)
  • Functions as a carrier molecule for certain minerals, hormones, fatty acids and assists in maintaining oncotic pressure in the capillaries
  • Low in malnutrition (<3.5 grams/dl), infection, burns, fluid overload, liver failure, cancer and nephrotic syndrome
  • Unreliable as a stand-alone marker for nutritional status since it is affected by a multitude of disease processes.
  • Older adults: in functionally impaired elderly, albumin has a low specificity for identifying nutritional status.

2. Pre-Albumin

  • Produced by the liver
  • Half-life 2-3 days (reflects changes in nutritional status sooner than albumin)
  • Affected by the same inflammatory states as albumin- infections and liver disease
  • Low in malnutrition:< 10 gm/dl severe depletion, 10-15 grams/dl moderate depletion
  • Can be low in liver failure and elevated in renal failure
  • More reliable indicator of acute changes in a patient’s nutritional status
  • Since it is degraded by the kidneys, any renal dysfunction causes an increase in pre-albumin serum levels.

3. Transferrin or Total Iron Binding Capacity (TIBC)

  • Half-life 10 days
  • Serum protein synthesized in the liver
  • Low in protein energy malnutrition (can also be affected by iron status as in chronic blood loss anemia causing an elevated transferrin level due to increased iron absorption)
  • Mild depletion 151-200 mg/dl
  • Moderate depletion 100-150mg/dl
  • Severe depletion, < 100 mg/dl
  • Transferrin also increases in renal failure. Oral contraceptives and estrogen also alter serum transferrin levels.
  • Poor serum marker for assessing nutritional status

4. Hemoglobin

  • Low hemoglobin leads to inadequate oxygen perfusion to cells resulting in decreased energy production affecting multi-functions-including healing and growth

5. Hematocrit

  • A volume measurement that verifies hemoglobin level

6. Lymphocyte count

  • Low lymphocyte count indicates decreased ability to fight off infections/increased susceptibility to infections
  • Chronic steroid use can decreased lymphocyte count
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3
Q

When evaluating malnutrition what should you focus on when conducting a history & physical assessment?

A

Focus on general characteristics, such as:

  • Edema, ankle and sacral
  • Subcutaneous fat loss
  • Muscle wasting
  • Ascites
  • Skin, mucous membranes, hair, nails

History should include:

  • Weight loss in past 6 months
  • Changes in dietary intake
  • Gastrointestinal symptoms (n,v, change in bowel habits)
  • Functional capacity (poor exercise tolerance, reduced mobility/endurance)
  • Disease and its relation to nutritional requirements (hx of cancer, crohn’s disease, rheumatoid arthritis. Cardiopulmonary disease, infection)
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4
Q

How do you determine a patient’s calorie needs?

A

Kilocalories per kilogram of body weight (may use actual or desired weight depending upon goal of therapy)

  • Average adult: 30kcal/kg or 13 kcal/lb of body weight/24 hours
  • For weight gain: 35 or more kcal/kg is appropriate
  • For weight loss: 25 kcal/kg
  • 1 lb of body weight = 3500 kcal
  • For fever: 7% increase in kcal/24 hours needed for each degree > 37.0C
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5
Q

How do you determine a patient’s fluid requirements?

A
  • One mL (cc) of fluid/kcal/24 hours (30-35 ml/kg of body weight) is usual- decaffeinated beverages
  • Elevation in vital signs, placements of drains, nausea/vomiting, diarrhea etc. requires an increase of 150mL/24 hours for each degree rise in body temperature above normal (37.0C)
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6
Q

How do you determine a patient’s protein requirements?

A
  • Protein required per day ranges from 0.8-2 grams/kg of body weight
  • Renal and hepatic diseases necessitate lower levels of protein due to inability of body to convert ammonia to urea in liver or to excrete urea via the kidneys
  • Protein is primary source of all nitrogenous waste products
  • Protein should account for 20% of daily kcal intake- needed for tissue growth
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7
Q

How do you determine a patient’s carbohydrate requirements?

A
  • Accounts for largest proportion of kcal in most diets- approx. 50% of daily kcal need
  • Patients with compromised respiratory function should eat less than average carbohydrate amounts since more oxygen (and release of co2) is required than for protein and fat metabolism
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8
Q

How do you determine a patient’s fat requirements?

A
  • Substituting fat for carbohydrates can reduce stress on the respiratory system since fat uses less oxygen and produces the least amount of carbon dioxide.
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9
Q

How do you determine a patient’s vitamin/mineral requirements?

A
  • Use recommended dietary allowance (RDA) as guided
  • Consult dietician for individual needs
  • Avoid over supplementation since the liver and kidneys excrete excess vitamins
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10
Q

How do you determine a patient’s electrolyte requirements?

A
  • Replace deficits as per laboratory results
  • Avoid excessive amounts, especially in renal disease
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11
Q

What are the 2 types of nutritional support?

A

1. Parenteral (vascular feeding): appropriate when GI tract is non-functional

2. Oral/Enteral feeding: appropriate when GI tract is functioning; the preferred method of feeding

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12
Q

When should patients begin receiving entral feeding?

A
  • Start early within the first 24-48 hours following admission
  • Withhold in setting of hemodynamic compromise
  • Gastric or small bowel feeding is acceptable
  • If high risk for aspiration, enteral access tube feeds should take place in small bowel
  • If enteral feeding > 6 weeks, refer for gastrostomy tube placement
  • If enteral feeding < 6 weeks, feed through trans-nasal tube
  • Withhold feeds for repeated high gastric residual volumes and place tip in small bowel
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13
Q

What are the 6 enteral routes of nutritional support?

A

1. Nasogastic tube:

  • Tip of tube in stomach
  • Most similar to route of normal digestion
  • Acid reflux common
  • Lack of integrity of gastric mucosa contradicts use

2. Nasoduodenal tubes:

  • End of tube located in duodenum
  • Acid reflux/aspiration less common
  • May require partially predigested form of formula

3. Nasojejunal tube:

  • End of tube located in jejunum
  • Formula type depends on area of jejunum that is used; intact for upper portion and hydrolyzed for mid to lower portion

4. Enterostomies: surgically created openings from exterior GI tract for long-term use (> 6 weeks) or when trans-nasal tube is contraindicated (ENT cancer)

  • Types include esophagostomy (distal tip in stomach)
  • Intact or blenderized formulas appropriate

5. Gastrostomy:

  • 2 types:
    • Percutaneous endoscopic gastrostomy (PEG)
      • Placed by GI endoscopy
      • Intact formula appropriate
      • Can be used 24 hours after placement
    • Percutaneous Gastrostomy (G tube)
      • Placed by Interventional Radiology using fluoroscopy
      • Intact formula appropriate
      • May be used in 24 hours

6. Jejunostomy:

  • Percutaneous endoscopic jejunostomy is an extension of percutaneous or endoscopic placed gastrostomy tube
  • Distal tip lies in jejunum
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14
Q

What are some complications with enteral feeding?

A
  • GI complications: diarrhea, cramping, constipation, gastric retention
  • Monitor for electrolyte imbalances and hyperglycemia
  • Consult a dietitian for formula and kilocalorie needs
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15
Q

How is parenteral nutritional support initiated?

A
  • Consult dietitian, nutritional support team, to include pharmacist
  • In patients who are not malnourished prior to acute illness, only initiate after first 7 days of hospitalization- if enteric nutrition not available or contraindicated
  • If evidence of malnutrition exists on admission and enteric nutrition contraindicated, begin parenteral nutrition following admission and stabilization.
  • Parenteral nutrition provided for a short duration (< 7 days) is not shown to produce outcome effect and can actually increase risks to patient.
  • Concentrations of dextrose > 10% require use of central line dedicated to parenteral nutrition.
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16
Q

What should you monitor on patients with parenteral nutrition?

A
  • Monitor blood glucose every 6 hours
  • Monitor electrolytes cbc, ca, mg, phos, lft’s and triglyceride levels
  • Infuse fat emulsions slowly
  • Involve parenteral nutrition team
  • Trend lab results weekly at minimum
17
Q

What are some complications associated with parenteral nutrition?

A
  • Metabolic complications, hyperglycemia, hypercapnia
  • High risk for infection due to glycemic content
  • Risk of pancreatitis with lipid infusion