Module 12.1 - Nutritional Considerations Flashcards
What are some characteristics of malnutrition?
- Independent risk factor for patient morbidity and mortality in hospitalized patients
- Prevalence as high as 40% among critically ill adults due to lack of proper evaluation and failure to optimize nutritional support early in hospitalization
- Associated with increased healthcare costs
- No standard methods of screening or diagnostic criteria
- Inflammation/infection has been identified as risk factor for malnutrition due to a marked increase in metabolism, leading to greater energy (caloric) requirements and loss of lean body mass
- Independent of type and severity of disease, duration of hospitalization impacts the risk of malnutrition; longer the stay = increase risk
- Laboratory markers are NOT reliable by themselves, should be used in conjunction with a thorough physical exam.
What are 6 laboratory measures of malnutrition?
1. Serum albumin
- Produced by the liver
- Half-life 14-20 days (synthesis requires amino acids and adequate liver function)
- Functions as a carrier molecule for certain minerals, hormones, fatty acids and assists in maintaining oncotic pressure in the capillaries
- Low in malnutrition (<3.5 grams/dl), infection, burns, fluid overload, liver failure, cancer and nephrotic syndrome
- Unreliable as a stand-alone marker for nutritional status since it is affected by a multitude of disease processes.
- Older adults: in functionally impaired elderly, albumin has a low specificity for identifying nutritional status.
2. Pre-Albumin
- Produced by the liver
- Half-life 2-3 days (reflects changes in nutritional status sooner than albumin)
- Affected by the same inflammatory states as albumin- infections and liver disease
- Low in malnutrition:< 10 gm/dl severe depletion, 10-15 grams/dl moderate depletion
- Can be low in liver failure and elevated in renal failure
- More reliable indicator of acute changes in a patient’s nutritional status
- Since it is degraded by the kidneys, any renal dysfunction causes an increase in pre-albumin serum levels.
3. Transferrin or Total Iron Binding Capacity (TIBC)
- Half-life 10 days
- Serum protein synthesized in the liver
- Low in protein energy malnutrition (can also be affected by iron status as in chronic blood loss anemia causing an elevated transferrin level due to increased iron absorption)
- Mild depletion 151-200 mg/dl
- Moderate depletion 100-150mg/dl
- Severe depletion, < 100 mg/dl
- Transferrin also increases in renal failure. Oral contraceptives and estrogen also alter serum transferrin levels.
- Poor serum marker for assessing nutritional status
4. Hemoglobin
- Low hemoglobin leads to inadequate oxygen perfusion to cells resulting in decreased energy production affecting multi-functions-including healing and growth
5. Hematocrit
- A volume measurement that verifies hemoglobin level
6. Lymphocyte count
- Low lymphocyte count indicates decreased ability to fight off infections/increased susceptibility to infections
- Chronic steroid use can decreased lymphocyte count
When evaluating malnutrition what should you focus on when conducting a history & physical assessment?
Focus on general characteristics, such as:
- Edema, ankle and sacral
- Subcutaneous fat loss
- Muscle wasting
- Ascites
- Skin, mucous membranes, hair, nails
History should include:
- Weight loss in past 6 months
- Changes in dietary intake
- Gastrointestinal symptoms (n,v, change in bowel habits)
- Functional capacity (poor exercise tolerance, reduced mobility/endurance)
- Disease and its relation to nutritional requirements (hx of cancer, crohn’s disease, rheumatoid arthritis. Cardiopulmonary disease, infection)
How do you determine a patient’s calorie needs?
Kilocalories per kilogram of body weight (may use actual or desired weight depending upon goal of therapy)
- Average adult: 30kcal/kg or 13 kcal/lb of body weight/24 hours
- For weight gain: 35 or more kcal/kg is appropriate
- For weight loss: 25 kcal/kg
- 1 lb of body weight = 3500 kcal
- For fever: 7% increase in kcal/24 hours needed for each degree > 37.0C
How do you determine a patient’s fluid requirements?
- One mL (cc) of fluid/kcal/24 hours (30-35 ml/kg of body weight) is usual- decaffeinated beverages
- Elevation in vital signs, placements of drains, nausea/vomiting, diarrhea etc. requires an increase of 150mL/24 hours for each degree rise in body temperature above normal (37.0C)
How do you determine a patient’s protein requirements?
- Protein required per day ranges from 0.8-2 grams/kg of body weight
- Renal and hepatic diseases necessitate lower levels of protein due to inability of body to convert ammonia to urea in liver or to excrete urea via the kidneys
- Protein is primary source of all nitrogenous waste products
- Protein should account for 20% of daily kcal intake- needed for tissue growth
How do you determine a patient’s carbohydrate requirements?
- Accounts for largest proportion of kcal in most diets- approx. 50% of daily kcal need
- Patients with compromised respiratory function should eat less than average carbohydrate amounts since more oxygen (and release of co2) is required than for protein and fat metabolism
How do you determine a patient’s fat requirements?
- Substituting fat for carbohydrates can reduce stress on the respiratory system since fat uses less oxygen and produces the least amount of carbon dioxide.
How do you determine a patient’s vitamin/mineral requirements?
- Use recommended dietary allowance (RDA) as guided
- Consult dietician for individual needs
- Avoid over supplementation since the liver and kidneys excrete excess vitamins
How do you determine a patient’s electrolyte requirements?
- Replace deficits as per laboratory results
- Avoid excessive amounts, especially in renal disease
What are the 2 types of nutritional support?
1. Parenteral (vascular feeding): appropriate when GI tract is non-functional
2. Oral/Enteral feeding: appropriate when GI tract is functioning; the preferred method of feeding
When should patients begin receiving entral feeding?
- Start early within the first 24-48 hours following admission
- Withhold in setting of hemodynamic compromise
- Gastric or small bowel feeding is acceptable
- If high risk for aspiration, enteral access tube feeds should take place in small bowel
- If enteral feeding > 6 weeks, refer for gastrostomy tube placement
- If enteral feeding < 6 weeks, feed through trans-nasal tube
- Withhold feeds for repeated high gastric residual volumes and place tip in small bowel
What are the 6 enteral routes of nutritional support?
1. Nasogastic tube:
- Tip of tube in stomach
- Most similar to route of normal digestion
- Acid reflux common
- Lack of integrity of gastric mucosa contradicts use
2. Nasoduodenal tubes:
- End of tube located in duodenum
- Acid reflux/aspiration less common
- May require partially predigested form of formula
3. Nasojejunal tube:
- End of tube located in jejunum
- Formula type depends on area of jejunum that is used; intact for upper portion and hydrolyzed for mid to lower portion
4. Enterostomies: surgically created openings from exterior GI tract for long-term use (> 6 weeks) or when trans-nasal tube is contraindicated (ENT cancer)
- Types include esophagostomy (distal tip in stomach)
- Intact or blenderized formulas appropriate
5. Gastrostomy:
- 2 types:
- Percutaneous endoscopic gastrostomy (PEG)
- Placed by GI endoscopy
- Intact formula appropriate
- Can be used 24 hours after placement
- Percutaneous Gastrostomy (G tube)
- Placed by Interventional Radiology using fluoroscopy
- Intact formula appropriate
- May be used in 24 hours
- Percutaneous endoscopic gastrostomy (PEG)
6. Jejunostomy:
- Percutaneous endoscopic jejunostomy is an extension of percutaneous or endoscopic placed gastrostomy tube
- Distal tip lies in jejunum
What are some complications with enteral feeding?
- GI complications: diarrhea, cramping, constipation, gastric retention
- Monitor for electrolyte imbalances and hyperglycemia
- Consult a dietitian for formula and kilocalorie needs
How is parenteral nutritional support initiated?
- Consult dietitian, nutritional support team, to include pharmacist
- In patients who are not malnourished prior to acute illness, only initiate after first 7 days of hospitalization- if enteric nutrition not available or contraindicated
- If evidence of malnutrition exists on admission and enteric nutrition contraindicated, begin parenteral nutrition following admission and stabilization.
- Parenteral nutrition provided for a short duration (< 7 days) is not shown to produce outcome effect and can actually increase risks to patient.
- Concentrations of dextrose > 10% require use of central line dedicated to parenteral nutrition.