Module 12: Nervous System (a) Flashcards

1
Q

Central Nervous System

-Components

A
  1. Brain
  2. Spinal Cord
    - CSF — CSF surrounds the brain and spinal cord for protection
    - BBB — The blood brain barrier separates and shields the CNS from the body’s periphery
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2
Q

CNS

-Major Structures in the Brain

A
  1. Forebrain (Prosencephalon)
    - Telecephalon
    - Diencephalon — Interbrain
  2. Midbrain (Mesencephalon) — Connects the pons to the diencephalon and includes the:
    - corpora quadrigemina
    - tegmentum
    - Cerebral peduncles
    - Connects the forebrain and the hindbrain
    - Tectum is involved w/ voluntary and involuntary motor movements
    - Flood of the midbrain contains the RED NUCLEUS and the SUBSTANTIA NIGRA
  3. Hindbrain (Rhombencephalon)
    - Cerebellum
    - Pons
    - Medulla
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3
Q

CNS

-Spinal Cord

A
  1. Long nerve that connects the brain and body

2. Continues from the Medulla oblongata and ends between the first and second lumbar vertebrae

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4
Q

PNS

-Components

A
  • 12 Cranial Nerves
  • 31 spinal nerves
  1. Somatic
    - Afferent (Sensory) — Ascending pathways — Carry Impulses from PNS to CNS
    - Efferent (Motor) — Descending pathways — Carry impulses from CNS to target organs like skeletal muscle
  2. Autonomic
    - Sympathetic
    - Parasympathetic
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5
Q

Nervous System

-Cell Types (2)

A
  1. Neurons

2. Neuroglia — Support the neurons of the CNS

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6
Q

Nervous System Cells

-Neurons

A
  1. Generates and transferes nerve impulses
  2. Specialized cells and do not need insulin to take up glucose**

3 components

  • Cell body - Located in the CNS — Cell bodies in the PNS are called ganglia
  • Dendrites - Receptor portion of the neuron — Carries nerve impulses toward cell body
  • Axons - carry nerve impulses AWAY from cell body — Typical neuron has 1 axon wrapped in myelin sheath — made of Schwann cells
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7
Q

Nervous System Cells

-Neuroglia Cells

A
  1. 2 Types of Myelinating Cells
    - Oligodendroglia — Form Myelin sheath around axons in the brain and spinal cord
    - Schwann Cells — Form Myelin sheath around axons in the PNS
  2. Non-Myelinating Schwann Cells
    - Provide metabolic support (Ex: astrocytes which are essencial components of BBB) —
    - Micróglia — Remove cellular debris
  3. Nodes of Ranvier — Where tight Schwann cells are pinched to create gaps — Improves speed of conduction of nerve impulse
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8
Q

Neurotransmitters

-Examples of substances

A
  1. Amino acids — GABA, Glyceine, Glutamate, aspartate
  2. Neuropeptídes — Endorphins
  3. Monoamines — Nor-epinephrine, serotonin, dopamine & histamine
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9
Q

Neurotransmitters

-Summation Definition

A
  1. Brings membrane closer to Threshold potential
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10
Q

Forebrain Functions

-Telencephalon

A
  1. The telencephalon consists of
    - Cerebral cortex
    - Basal Ganglia
  2. The Cerebrum makes up the forebrain — Divided into right and left hemispheres by the longitudinal fissure
  3. Cerebral cortex — Outer layer of the cerebrum and is made up of gray matter
    - White matter lies beneath the cortex and contains myelinated axons
  4. The Cortex can be further divided into functional lobes:
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11
Q

Forebrain Functions

-Telencephalon Functional Lobes

A
  1. The Frontal Lobe
    - Prefrontal area — Responsible for Goal-directed behavior, Short term memory, complex thought
    - The rest of the frontal lobe coordinates motor movements
    - Broca’s area — Speech and language interpretation — Motor speech — Inferior portion of frontal lobe
  2. Parietal lobe — Somatic Sensory input
  3. Occipital lobe — Visual cortex which receives input from the retinas
  4. Temporal lobe — Primary auditory cortex, equilibrium, emotion, & memory
    - WERNICKE’s area —Speech and language interpretation — Speech interpretation
  5. Limbic Structures — Control emotions, short-term memory
  6. Nuclei of the basal ganglia — Masses of gray matter that are involved in the initiation and planning of learned motor activities.
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12
Q

Forebrain Functions

-Diencephalon

A

Second part of the forebrain and is the land of THALMUS

  1. Epithalmus — Pineal body — secretes melatonin
  2. THALMUS — Relays motor and sensory signals to the cortex — Integrates afferent impulses and interprets info such as auditory, visual, tactile and taste
  3. Hypothalamus — Responsible for Maintenence of the internal environment - Regulates autonomic nervous system Ex: body temp,endocrine function, emotional expression and control of the pituitary gland
  4. Subthalamus — Part of the basal ganglia and connects to the substantia nigra of the midbrain
    —Subthalmus plays large role in extrapyramidal system which is important for FINE MOTOR MOVEMENT
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13
Q

Forebrain Functions

-Limbic System

A
1. Consists of an arc of structures between the telencephalon and the diencephalon 
Structures include the 
-Amygdala
-Hippocampus
-Fórnix
-Hypothalamus 
-Autonomic Nuclei
  1. Limbic system function — Involvement in primitive behavioral responses such as emotion, fear, anger, pleasure, feeding, biological rhythms and sense of smell
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14
Q

Midbrain

-Components

A
  1. Tectum — Visual & Auditory motor movements
  2. Tegmentum
    - Red Nucleus — Receives sensory information from the cerebellum and sends it to the cervical spinal cord
    - Substantia nigra — Synthesizes dopamine
  3. Cerebral Peduncles — Contain white matter tracts that contain EFFERENT nerves that relay signals between cortex and brain stem
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15
Q

Hindbrain

-Components

A
  1. Cerebellum — Responsible for regulation & coordination of movement, posture, and balance — Finger nose or heel shin test
    - Controls conscious and unconscious muscle synergy required for maintaining balance and posture
    - Does not initiate movement, just helps coordinate it
  2. Pons — Transmits information from cerebellum to the brainstem
    - Important for the control of RESPIRATION**
    - Nuclei of the 5th and 8th cranial nerves are located in the pons
  3. Medulla Oblongata — lowest portion of the brainstem and is responsible for various reflex activities
    —Ex: Heart rate, respiration, BP, coughing, sneezing, swallowing, vomiting
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16
Q

Protective Structures of the Brain

A
  1. Dura matter — Rigid double thickness membrane
  2. Arachnoid — spongy membrane under the dura
  3. Pia Matter — delicate membrane closely adhering to brain and spinal chord surface providing support for vessels
17
Q

Vertebral Column

A
  1. Cervical - 7
  2. Thoracic - 12
  3. Lumbar - 5
  4. Sacral - 5 fused
  5. Coccygeal - 4 fused
18
Q

Spinal Cord

-Components

A
  1. Grey Matter — Forms the inner core and is the central part of the spinal cord
  2. White Matter — Contains spinal tracts
    - Large bundles of nerves that carry information up and down spinal cord
    - Some are ascending and descending
19
Q

Spinal Cord

-Grey Matter

A
  1. Posterior Horn — Back part of the wing of the gray matter/butterfly shape
    - Receives information from receptors in skeletal muscles, organs, and glands
  2. Anterior Horn — Containts nerve cell bodies for EFFERENT or motor pathways
20
Q

Reflexes

-Structures necessary to Elicit a Reflex?

A
  1. Receptor
  2. Afferent & Efferent neuron
  3. Effector muscle or gland
  4. Reflexes are usually perceived before the sensory event is processed in the brain TEST
21
Q

Blood Supply to the Brain

A
  1. Internal carotid and vertebral artery supply the brain w/ arterial blood
  2. Circle of Willis — 5 arteries come together to form a circle — helps provide opportunity for collateral or compensatory blood flow
  3. Blood Brain Barrier —Highly selective semi-permeable membrane that separates circulating blood from extracellular fluid in the CNS
    -ASTROCYTES are Neuroglia that surround blood vessels in CNS to form BBB
    -
22
Q

Cranial Nerves

-Info

A
  1. CN’s are myelinated w/ Schwann cells
    - Groups of cell bodies in the PNS are ganglia — In the CNS they are called nuclei
  2. PNS nerves have a sheath of connective tissue that provides protection and support
  3. PNS operates for both afferent and efferent functions
  4. CN’s are classified as peripheral nerves, but DO project to nuclei in the brain and brainstem
  5. Most nerves are Mixed (Sensory and motor)
23
Q

CN

-Sensory or Motor

A
  1. CN I, II, VIII are Sensory ONLY
  2. CN III, IV, VI & XI & XII are BOTH but primarily Motor
  3. The rest are Both
24
Q

Spinal Nerves

-Info

A
  1. The names of the spinal nerves correlate w/ the vertebral level from which they exit
  2. They are mixed sensory and motor nerves & arise from the anterior and posterior horns of the spinal cord
  3. These nerves travel from the spinal cord then merge into groupings referred to as Plexus
25
Q

Spinal Nerves

-Plexuses

A
  1. Cervical Plexus — Covers the diaphragm, neck and hyoid bone
  2. Brachial Plexus — Provides impulses to the arm
  3. Lumbar Plexus — Carries impulses from the hip, gluteus, thigh, foot and perineum
  4. Coccygeal Plexus — Correlates to the skin of the coccyx
26
Q

Spinal Nerves

-Dermatomes

A
  1. When sensory signals arise from a particular area o the body, these are known as dermatomes
  2. Important for assessing spinal compression and for diagnosing things like varicella zoster
27
Q

ANS

-Info

A
  1. The autonomic NS is what regulates most of the involuntary functions of our internal organs
  2. Components of the ANS are in the CNS and PNS
  3. Peripheral autonomic nerves carry mainly EFFERENT fibers, meaning motor function
    - Consist of both myelinated and un-myelinated neurons
  4. Myelinated neurons are known as Pre-Ganglionic **
  5. Un-myelinated neurons are known as POST-Ganglionic **
28
Q

ANS

-Sympathetic NS

A
  1. Mobilizes energy stores in times of need — FIGHT OR FLIGHT Response
  2. Receives Innervation signals from cell bodies located between T1 - L2 Known as Thoracolumbar division
  3. Ganglia of the SNS Deliver info to the body about stress and impending danger
  4. Adrenal Medulla releases Epinephrine and norepinephrine
    - Epinephrine release from adrenal medulla causes increase glucose levels (glycogenolysis in liver), breakdown of adipose tissue and glycolysis in muscle tissue
    - Nor-Epinephrine acts on alpha receptors which cause vasoconstriction and increase in Blood pressure
    - Stimulation of beta receptors cause vasodilation and increased blood flow to muscles
29
Q

ANS

-Parasympathetic NS (PNS)

A
  1. Functions to conserve and restore energy — REST AND DIGEST
  2. Nerve cell bodies arise in the CNS — Receptor organs receive Innervation from cell bodies in the CN nuclei and sacral region of spinal cord
    —This is known as the CRANIOSACRAL DIVISION
  3. When PNS is activated
    - Reduced HR, improved digestion, Increased peristalsis and relaxation of sphincters, CNS will cause pupillary constriction, tear secretion and salivation
    - Parasympathetic fibers activate certain regions so the division has less widespread effect
30
Q

Neurotransmitters of the Autonomic NS

A
  1. Both Sympathetic and Parasympathetic pre-ganglionite fibers use Acetylcholine**
  2. In the Postgalnglionic fibers
    - Parasympathetic fibers use acetylcholine
    - Sympatetic postganglionic fibers use Nor-Epinephrine
31
Q

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A

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32
Q

Intervertebral Disks

-Structure

A
  1. Nucleus Palposus — Located in the middle of each disc — Mass of jelly like fibers that is mainly water — Helps with spinal mobility
  2. Annulus Fibrosis — Tough outer exterior that encircles the disk — Some people tear their annular fibrosis