Module 12

Question 1

Benefits of controlled release of bioactive molecules in vivo

Answer 1

Controlled release is usually essential to avoid systemic administration

Question 2

Physical entrapment, hydrophobic microparticles, non-specific affinity, specific affinity, and covalent attachment

Answer 2

PE: lots of blue strings and red dots
HM: big green dot with red dot inside and some blue strings
NSA: positive and negative charges positive on red dot
SA: blue wings with red dots
CA: black rods connected to red dots

Question 3

Slide 13: Figure 5

Answer 3

Fibrin matrices to used to fuse the carpal joint complex

Question 4

Slide 17: Figure 8

Answer 4

Release of signal 1: low affinity for the matrix
Release of signal 2: intermediate affinity for the matrix
Release of signal 3: high affinity for the matrix