module 1.08 Flashcards
what two cell types do cartilage contain?
immature chondroblasts- secrete extracellular matrix of cartilage
chondrocytes- mature cartilage cells, located in spaces called lacunae. (derived from chondroblasts)
How are metabolites exchanged in cartilage?
Cartilage has no blood vessels so all exchange is through diffusion.
what are the 3 types of cartilage found in the adults body?
hyaline cartilage, white fibrocartilage, elastic cartillage
Give examples of where hyaline cartilage is found in the body?
- covers the end of synovial joints (articular cartilage)
- connects ribs to sternum (costal cartilage)
- forms the larynx and part ofteh nose and reinforces trachea and bronchi
what are the main characteristics of white fibrocartilage and where is it found in the body?
- less matrix an more collagen than other cartillage
- compressible and able to resist high pressure
- found between the vertebrae (intervertebral disc) and in the knee joint (meniscus)
what are the characteristics of elastic cartilage and where is it found?
- high levels of elastic fibres
- the external ear where it forms the pinna and the eustachian tube
- the throat where it forms the epiglottis
where is the perichondrium found?
-it is a fibrous layer which surround hyaline and elastic cartilage ( with the exception of articular cartilage in synovial joints)
what is the perichondrium made up of (inner and outer layer)?
Contains fibroblasts along with type I collagen in the outer layer and chondroblasts in the inner layer.
what is the periosteum?
- it lines the outside surface of all bones
- vascularised
- perichondrium is continuous with periosteal bone which is continuous with surrounding connective tissue which forms the periosteum as it becomes vascularised
How is bone classified and why?
Bone is classified as connective tissue because it shows the characteristics of all connective tissues
what are the characteristics of all connective tissue?
relativley acellular, with osteogenic (bone generating) cells widely seperated with in abundant extracellular matrix
what are the 4 types of cell in bone?
- osteocytes
- osteoclasts
- osteoblasts
- bone lining cells (osteogenic progenitor cells)
What is the function of osteoblasts?
- make new bone matrix
- synthesise and secrete collagen fibres
what are the characteristics of osteocytes?
- found in more mature bone (formed from osteoblasts)
- maintain the daily cellular activities of the bone tissue: exchange of nutrients and waste products with the blood
- sense stress placed on bone matrix
what are the characteristics of osteoclasts?
- removal of old bone
- originate from monocyte precursors
- multinucleated
- plasma membrane facing the bone surface is ruffled and releases lysozymes and acids that digest and dissolve the protein and mineral matrix
what are the functions of bone?
- locomotion
- support
- mineral homeostasis
- protection
- hematopoiesis
- (fat storage)
what 4 cells are found in the bone marrow cells?
- stem cells (MSCs)
- RBCs
- WBCs
- Adipocytes
What are the 3 structural classifications of joints?
- fibrous
- cartilaginous
- synovial
what type of joint are skull suture, syndesmosis and gomphosis examples of?
fibrous joints
what are the 3 types of muscle?
skeletal, smooth, cardiac
what are the characteristics of skeletal muscle?
voluntary muscle, attached to bones and responsible for skeletal movements, controlled by peripheral nervous system
what are the characteristics of smooth muscle?
Involuntary muscles, found in walls of hollow internal organs. control of autonomic nervous system
what are the characteristics of cardiac muscle?
Involuntary muscles, found in the walls of the heart. Under control of autonomic nervous system.
what are the 6 main muscle types?
- circular
- convergent
- multipennate
- unipennate
- Bipennate
- parallel
what are the 3 muscle compartments of the thigh and what movements is each responsible for?
Anterior comparment- hip flexion and knee extension
Medial compartment - the adductor group as they primarily produce hip addduction
Posterior compartment- hip extension and knee flexion
what is the function of a tendon?
- to transmit forces generated from the muscle contraction through the bone to elicit movement
- their fibro-elastic composition gives them the strength required to transmit large mechanical forces
where are tendons found?
- tendons are situated between bone and muscle
- each muscle has two tendons one proximally and one distally
- proximal attachment is known as the origin
- distal attachment is known as the insertion