Module 10 Flashcards
Major and trace minerals
Major- need over 100 mg/day (Na, Mg, K, C, etc)
Trace-need less than 100 mg/day (Zn, Cu, Fe, etc.)
Ca we need the most of 1000 mg/day.
Fe is the trace mineral we need the most 8 mg/18 mg
Se
China, New Zealand
RDA: 55 mcg/day
UL = 400 mcg/day
Zn
RDA: 8/11 mg/day (women/men)
UL: 40 mg/day
I
Canadian law: iodized salt (EXCESS)
Insufficient I in Africa, South America…
RDA: 150 mcg/day
UL: 1100 mcg/day
Minerals and functions
- Mineral interactions between each other.
- Diverse functions: cofactor, part of structure of body compounds, regulating muscle contraction, and optimal immunity.
Controlling mineral levels in the body
Absorption from GI tract: absorb what we need, excess lost in feces.
Excretion
Iron
Fe
In adult: 2-5 g Fe in body (No free Fe in blood).
Where is iron found in the body?
1.Functional/metabolic purposes: 70% hemoglobin (RBC), 4% myoglobin (muscle), and <1% Coenzyme.
2. Storage (Liver): man 1g, woman 300mg, overstorage as hemosiderin.
3. Transport: from liver stores to bone marrow (transferrin protein, transports it).
1. is 75%
2. is 25%
3. is <1%
Stages of Iron depletion
- Progressive decrease in liver stores (serum ferritin decreases, hemoglobin is still normal)
- Exhaustion of liver stores (transferrin saturation decreases, but hemoglobin is still normal, exhaustion/exercise performance decreases).
- Hemoglobin decreases (IDA: iron deficiency anemia, pale rood blood cells)
Iron status: Who is at the highest risk and why?
Issue: #1 nutrient deficiency world-over.
Highest risk: pregnant women (need 27 mg Fe/day), infants, adolescence.
Contributing factors of iron depletion
Normal diet (6-7 mg Fe/1000 Kcal) 8mg/day for men.
Poor absorption
Excess loss (heavy menstruation)
Iron Bioavailability
How well we absorb and use the nutrients.
Food Sources of iron
RDA 18/8 mg/day (women/men)
Red meat
Vegetarians: x1.8 =14 mg/day(men), 32 mg/day(women)
Challenge: Maintaining iron levels from adolescence to early 20s:
- Growth spurt.
- Menstruation
- Changes in diet
- Increased exercise: increases Fe demand
Are iron supplements the answer?
constipating, may interfere with absorption of other minerals, mask other deficiency or other clinical situations, UL of 45 mg/day.
Challenge in Canada
the Sedentary Lifestyle
Iron Chelating substances
claw (hang onto and assist absorption)
Heme
Vitamin C (better absorption)
Amino Acids