Module 10 Flashcards

1
Q

Major and trace minerals

A

Major- need over 100 mg/day (Na, Mg, K, C, etc)
Trace-need less than 100 mg/day (Zn, Cu, Fe, etc.)
Ca we need the most of 1000 mg/day.
Fe is the trace mineral we need the most 8 mg/18 mg

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2
Q

Se

A

China, New Zealand
RDA: 55 mcg/day
UL = 400 mcg/day

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3
Q

Zn

A

RDA: 8/11 mg/day (women/men)
UL: 40 mg/day

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4
Q

I

A

Canadian law: iodized salt (EXCESS)
Insufficient I in Africa, South America…
RDA: 150 mcg/day
UL: 1100 mcg/day

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5
Q

Minerals and functions

A
  1. Mineral interactions between each other.
  2. Diverse functions: cofactor, part of structure of body compounds, regulating muscle contraction, and optimal immunity.
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6
Q

Controlling mineral levels in the body

A

Absorption from GI tract: absorb what we need, excess lost in feces.
Excretion

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7
Q

Iron

A

Fe
In adult: 2-5 g Fe in body (No free Fe in blood).

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8
Q

Where is iron found in the body?

A

1.Functional/metabolic purposes: 70% hemoglobin (RBC), 4% myoglobin (muscle), and <1% Coenzyme.
2. Storage (Liver): man 1g, woman 300mg, overstorage as hemosiderin.
3. Transport: from liver stores to bone marrow (transferrin protein, transports it).
1. is 75%
2. is 25%
3. is <1%

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9
Q

Stages of Iron depletion

A
  1. Progressive decrease in liver stores (serum ferritin decreases, hemoglobin is still normal)
  2. Exhaustion of liver stores (transferrin saturation decreases, but hemoglobin is still normal, exhaustion/exercise performance decreases).
  3. Hemoglobin decreases (IDA: iron deficiency anemia, pale rood blood cells)
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10
Q

Iron status: Who is at the highest risk and why?

A

Issue: #1 nutrient deficiency world-over.
Highest risk: pregnant women (need 27 mg Fe/day), infants, adolescence.

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11
Q

Contributing factors of iron depletion

A

Normal diet (6-7 mg Fe/1000 Kcal) 8mg/day for men.
Poor absorption
Excess loss (heavy menstruation)

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12
Q

Iron Bioavailability

A

How well we absorb and use the nutrients.

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13
Q

Food Sources of iron

A

RDA 18/8 mg/day (women/men)
Red meat
Vegetarians: x1.8 =14 mg/day(men), 32 mg/day(women)

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14
Q

Challenge: Maintaining iron levels from adolescence to early 20s:

A
  1. Growth spurt.
  2. Menstruation
  3. Changes in diet
  4. Increased exercise: increases Fe demand
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15
Q

Are iron supplements the answer?

A

constipating, may interfere with absorption of other minerals, mask other deficiency or other clinical situations, UL of 45 mg/day.

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16
Q

Challenge in Canada

A

the Sedentary Lifestyle

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17
Q

Iron Chelating substances

A

claw (hang onto and assist absorption)
Heme
Vitamin C (better absorption)
Amino Acids

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18
Q

Heme

A

10-15% absorption (fantastic absorption)

19
Q

Iron-Complexing/ Precipitating substances

A

Phytates
Oxalates
Tannins
Phosphates

20
Q

Phytates

A

Whole grains

21
Q

Oxalates

A

green leafy vegetables
Fe<0.01% absorption

22
Q

Tannins

A

red wine, tea
prevent absorption

23
Q

Phosphates (P)

A

its in everything
Meat, cola, processed food
Bind up iron and lower absorption

24
Q

Calcium

A

In body: 1200-3000 g

25
Functions of calcium
Enzyme reactions, nerve conductor, muscle contraction
26
Dietary sources of calcium
RDA: 1000 mg/day 9-18 yr olds: 1300 mg/day 19-50 yr old: 1000 mg/day 51-70 yrs old: increases UL (for adults): 2500 mg (very wide safety margin) Milk, yogurt, fortified soy beverage, sardines, kale cooked.
27
Calcium Bioavailability
1 cup milk---> 315 Ca mg (% absorbed 32.1%)
28
Calcium and bone health
Ca(in)=Ca(out)
29
Calcium Absorption
Absorb 30-50% of Ca in foods. Depends on form of Ca in food, Vit D, precipitating and chelating substances.
30
Calcium in bone
exists as complex: hydroxyapatite. Ca:P; 2:1 (ideal), 1:1 (ok), 1:4 (adverse effects)
31
Factors affecting calcium balance
1. Phosphorus 2. Protein: excess animal protein intake can increase urinary Ca loss. 3. Precipitating (decrease Ca absorp) and Chelating (increase Ca absorp) Substances. 4. Physical Activity- the stimulus for laying down bone (weight bearing excersise) 5. Smoking 6. Alcohol 7. NaCl Fruit and vegetables
32
Calcium deficiency
Osteoporosis
33
Sodium Roles
fluid balance, muscle contraction, nerve conduction
34
Main source of sodium in Canadian Diet
Salt 1 teaspoon=2.3 g (UL) 2300 mg
35
Sodium: How much are we eating?
AI=1.5 g UL=2.3g Current=3.4 g Almost the entire canadian population has intakes above the UL.
36
Major contributors to sodium intake in the Canadian Diet
Processed foods account for 75% for sodium intake.
37
Phytochemicals
"Not essential"; important for optimal health and chronic disease mitigation. Limonene (citrus) lignin (flax) Isoflavone (soy) Indole-3-carbinol Sulforaphane
38
Functional foods
confer health advantage beyond nutritional Food: bran muffins, flax and broccoli
39
Nutraceuticals
pill, powder "supplement" Pharmaceuticals
40
Why are we concerned about excess sodium?
Hypertension CHD Stroke Kidney Diesease Dementia Eye damage
41
Hypertension
Healthy blood pressure <120/80 mm Hg One in four canadians 90% Canadians who live >80yrs
42
Dash diet
dietary approaches to stop hypertension
43
Effect of calcium intake and other factors affecting Bone mass density (BMD):
In growing children, total bone mass increases as the bones grow larger. During puberty, bone mass increases rapidly, and sex differences in bone mass appear. Men achieve a higher peak bone mass than women do. Both men and women lose bone slowly after about age 35. In women bone loss is accelerated for about 5 years after menopause.