Module 1 - Introduction, Dietary Reference Intakes Flashcards

1
Q

What are DRIs?

A

A set of nutrient-based reference values

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2
Q

What do DRIs serve as a basis for?

A

almost all federal and state food & nutrition programs and policies (ex: SNAP & WIC)

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3
Q

DRIs apply to who?

A

only to healthy people

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4
Q

The DRI was published by who?

A

the national academy of sciences

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5
Q

What year was the DRI first published in?

A

1941

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6
Q

Why may DRIs differ for individuals?

A

because they are at different life stages

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7
Q

What are the 5 stages of the development of nutritional deficiency?

A
  1. dietary inadequacy (assessed by diet)
  2. decreased reserves (assessed biochemically)
  3. decreased levels in body fluids (assessed biochemically)
  4. decreased function/change in enzyme activity (assessed by anthropometric/biochemical)
  5. clinical symptoms (assessed clinically)
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8
Q

What are studies used to determine DRIs?

A
  1. animal models
  2. human feeding studies
  3. observational studies
  4. randomized controlled trials
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9
Q

When are animal models used?

A

used when human data is not available

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10
Q

Human feeding studies involve what?

A

controlled feeding studies in metabolic wards

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11
Q

Observational studies look at what?

A

free living subjects

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12
Q

Which study is used to determine if DRI is considered gold standard?

A

randomized controlled trials

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13
Q

Why may adjustments be made to the DRI?

A

because the body’s ability to absorb and use nutrients can vary depending on the food source or whether supplements are used

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14
Q

What does EAR stand for?

A

estimated average requirements

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15
Q

What is EAR?

A

the average daily nutrient intake level estimated to meet the requirement of half the healthy individuals in a particular life stage and gender group

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16
Q

The EAR plans intakes for who/what?

A

groups

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17
Q

What is the EAR the basis for?

A

RDA values

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18
Q

Why are studies to determine EAR limited?

A

limited due to few human studies

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19
Q

The EAR is an indicator used for what?

A

indicator used for nutrition intake adequacy which is important in determining requirement

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20
Q

What is the vit D EAR for females and males aged 19-30?

A

400 IU

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21
Q

True or False: The EAR should be used as the goal for mean intake?

A

False (EAR is estimated to meet the requirement of half the healthy individual but can result in half the inadequacy)

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22
Q

What does RDA stand for?

A

recommended dietary allowance

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23
Q

What are RDAs?

A

the average daily nutrient intake level sufficient to meet the nutrient requirements of nearly all (97-98%) healthy individuals in a particular life stage and gender group

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24
Q

Usual intake at RDA would have

A

low inadequacy probability

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25
Q

What is the vitamin D RDA for females and males aged 19-30?

A

600 IU

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26
Q

What is the ideal process for establishing an RDA?

A
  1. select healthy, representative sample of population
  2. determine EAR
  3. assess range of individual variability
  4. calculate allowances to cover needs of nearly all healthy individuals
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27
Q

What is the RDA equation?

A

RDAs = EAR + 2SD

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28
Q

What does AI stand for?

A

adequate intake

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29
Q

What is AI?

A

the recommended average daily intake level based on observations or experiments with healthy people

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30
Q

When is AI used?

A

when an RDA cannot be determined (insufficient data available, cannot do randomized trial)

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31
Q

What is the AI for vitamin D in infants aged 0 to 6 months and 6 to 12 months?

A

400 IU

32
Q

What does AI represent?

A

the group mean intake of an apparently healthy group of people

33
Q

Similar groups with mean intake at or above ai can be assumed to have what?

A

low prevalence of inadequate intakes

34
Q

What happens when mean intakes of groups are below ai?

A

it is NOT possible to make any assumption about inadequacy

35
Q

Issuance of an AI is an indication of what?

A

that more research is needed

36
Q

When can AI be replaced by EAR?

A

when more evidence/data is available

37
Q

There is less certainty about ________ than about RDAs

A

AI

38
Q

AIs must be used with

A

reservation and caution

39
Q

What is Tolerable upper Intake Level (UL)?

A

the maximum daily nutrient intake that is unlikely to cause health risks for most people

40
Q

As intake increases above the UL, the potential risk of adverse effects may _______

A

increase

41
Q

What is the UL of vitamin D in females and males aged 19 to 30?

A

4,000 IU

42
Q

What are the challenges to setting UL?

A
  1. absence of dose-response data
  2. few studies in humans or animals
  3. few surveillance studies to establish no-observed adverse effect level
  4. available databases concentrate on supplement intake, not total
  5. significant differences in bioavailability
43
Q

The ULs grew out of what?

A

increased fortification and supplements

44
Q

What does it mean if someone is below the EAR or RDA on the DRI curve?

A

risk of inadequacy increases

45
Q

What does it mean if we go above the UL on the DRI curve?

A

risk of adverse effect increases

46
Q

RDA accounts for who?

A

majority of healthy individuals

47
Q

EAR accounts for who?

A

50% of people

48
Q

The requirements for iron are

A

the same up to 14, then biological sex changes it (menstruation)

49
Q

RDAs and AIs are

A

levels of intake recommended for individual

50
Q

Nutrient needs may be based on

A

body size

51
Q

For purposes of the EAR or UL, what was used to establish age/gender values?

A

reference weights and heights

52
Q

Within the 4-8 year old range, who would have a smaller requirement? A 4 year old or an 8 year old?

A

4 year old (RDA or AI cover both)

53
Q

Is dietary assessment an exact science?

A

no

54
Q

What is dietary assessment?

A

The best estimate of individual or group intake

55
Q

What does dietary assessment calculate?

A

The probability of inadequacy for individuals and prevalence of adequacy within a group

56
Q

Assessing an individual’s nutrient adequacy requires knowing what?

A
  1. individual’s requirement for that nutrient
  2. individual’s long-term usual intake of that nutrient
    (neither are usually known –> assumptions are needed)
57
Q

When assessing an individual’s diet we assume what?

A

that the individual’s requirement is the same as the EAR

58
Q

Is an RDA appropriate for assessing groups?

A

no, it meets or exceeds requirements of 97%-98% of individuals. using RDA would overestimate the proportion of the group at risk of inadequacy

59
Q

What judgement can you make if usual intake is equal to RDA?

A

intake is adequate

60
Q

RDAs can be used in planning for what?

A

groups and individuals, but not in assessing adequacy or intake

61
Q

What would happen if an RDA was used to assess groups?

A

it would overestimate the proportion of the group at risk of inadequacy

62
Q

What judgement about nutrient adequacy can you make if usual intake is < EAR?

a. intake is inadequate
b. intake is adequate
c. intake is similar to RDA

A

a. intake is inadequate

63
Q

What judgement about nutrient adequacy can you make if usual intake is equal to RDA?

a. intake is inadequate
b. intake is adequate
c. intake is similar to EAR

A

b. intake is adequate

64
Q

In individuals what do EARs examine?

A

examine the possibility of inadequacy

65
Q

In groups, what do EARs examine?

A

examine the prevalence of inadequate intakes within a group

66
Q

What does it mean if an individuals usual intake is at or above the RDA?

A

they have low probability of inadequacy

67
Q

What is RDA not used to assess?

A

not used to assess intakes of groups

68
Q

What does it mean if an individuals usual intake is at/above the AI?

A

they have a low probability of inadequacy

69
Q

What does it mean if a groups mean intake is at/above the AI?

A

low prevalence of inadequate intakes

70
Q

What does it mean if an individuals usual intake is above the UL?

A

they may be at risk of adverse effects

71
Q

What are ULs used to estimate?

A

used to estimate the % population at potential risk of adverse effects from excessive nutrient intake

72
Q

What are the limitations of DRIs?

A
  1. EAR may be based on data from limited number of individuals
  2. Precise variation in requirements is approximated
  3. Normal distribution
73
Q

What are DRIs used for?

A
  1. assess diets of individuals and populations
  2. basis for nutrition education
  3. food assistance program planning (ex: school meals, WIC)
  4. to assess impact of interventions
  5. food fortifications
  6. food products
74
Q

Suzanna is a vegetarian and wants to know what iron intake she should be eating. What DRI level do you recommend?

a. EAR
b. RDA
c. AI
d. UL

A

b. RDA

75
Q

You are conducting a research project where you are comparing US children (9-10 y/o) dietary vitamin D intake with recommended levels. Which DRI level should you use?

a. EAR
b. RDA
c. AI
d. UL

A

a. EAR

76
Q

Which DRI level do infants use?

A

AI

77
Q

Which DRI level do kids, aged 9-10, use?

A

EAR