Module 1 Flashcards
stage of lung development at 16-25 weeks gestation that consists of canaliculi branching out of terminal bronchioles to form an acinus composed of respiratory bronchioles, alveolar ducts, and alveolar sacs
Carnalicular Stage
functional unit of the lung composed of about 6 respiratory bronchioles, alveolar ducts, and alveolar sacs
acinus
stage of lung development at 25-36 weeks gestation in which terminal saccules continue to elongate, branch and widen
septa between saccules still thick at the beginning of this stage
Saccular Stage
alveolar ducts that are elongating, branching and widening in the saccular stage of lung development
terminal saccules
At ____ weeks,
All generations of conducting and respiratory bronchioles are formed
Blood-air barrier is reduces to 3 thin layers
36
Layers of ________:
Type I pneumocytes
fusal basal membrane
capillary endothelium
Blood-air Barrier
stage of lung development at 36 weeks gestation - 3-8 years old in which saccular epithelium begins to fold over elastin and collagen fibers to form an epithelial “tube” or alveolar septum
*Initially, a primary septum separates the alveolar saccules, containing a double layer of capillaries
Alveolar Stage
onset of physiological jaundice (TSB >7 mg/dL)
after 36 hours
onset of breastfeeding-associated jaundice (TSB >7 mg/dL)
2-4 days
onset of breastmilk jaundice (TSB >7 mg/dL)
4-7 days
peak time of physiological jaundice
3-4 days in formula-fed infants
slightly later in Asian + Asian-American infants
5-7 days in breastfed infants
peak time of breastfeeding-associated jaundice
3-6 days
peak time of breastmilk jaundice
5-15 days
peak TSB of physiological jaundice
5-12 mg/dL in formula-fed infants
7-14 mg/dL in breastfed and Asian + Asian-American infants
peak TSB of breastfeeding-associated jaundice
> 12 mg/dL
peak TSB of breastmilk jaundice
> 10 mg/dL
incidence of physiological jaundice in full-term infants
50-60%
incidence of breastfeeding-associated jaundice in full-term infants
12-13%
incidence of breastmilk jaundice in full-term infants
2-4%
characteristics of breastfeeding-associated jaundice in full-term infants
jaundice appears within 1st week of life poor feeding weight loss dehydration signs infrequent urine output delayed meconium passage
characteristics of breastmilk jaundice in full-term infants
jaundice appears after 1st week of life and persists for up to 12 weeks of life
feels well
normal weight gain
normal urine output
onset of pathological jaundice
rises quickly, within 24 hours
peak time of pathological jaundice
24 hours
characteristics of pathological jaundice
visible jaundice persists after 1st week of life
poor feeding
weight loss
Risk factors:
cephalohematoma
ABO blood group or Rh (D) incompatibility
polycythemia
peak TSB of pathological jaundice
> 13 mg/dL
normal NB Hct
43-63%
normal NB Hgb
14-20 g/dL
normal NB WBC
10-30
normal NB PLT
150,000-400,000