Modul 16 pt 2 Flashcards
What is the term used for blood flowing through body tissues?
Tissue Perfusion
What is the purpose of Tissue perfusion?
Delivery of Oxygen and nutrients
& the removal of CO2 and metabolic waste
Blood flow is also really important in what three functions?
Gas exchange in lungs
Nutrient absorption in GI tract
Urine formation in Kidneys
What is the term used for automatic blood flow to each tissue in proportion to its requirement at any given time?
Autoregulation
What does autoregulation do?
Changes arterial diameters
What are two types of short termed auto-regulation of tissue perfusion?
Myogenic control
Metabolic control
The vasodilation of arterioles and relaxation of pre capillary sphincters during decline of O2 and substances in metabolic active tissue
Metabolic Control
What is the major factor in Metabolic control that causes vasodilation?
NO (nitric oxide)
This is the most potent vasoconstrictor known that aids in metabolic control
Endothelins
This short term control is responses of smooth muscle that keeps tissue perfusion constant despite tissue pressure
Myogenic control
How does the myogenic control keep pressure constant?
Passive stretch
Reduced stretch
Vasoconstriction in metabolic situations is due to sympathetic ______ and ________.
Stimulation
Endothelins
How does passive stretch promote increased tone and vasoconstriction?
It is increased intravascular pressure
What does reduced stretch promote?
Vasodilation that increases blood flow to tissues
What is a long-term regulation that occurs when short-term regulation cannot meet tissue nurtrient requirements?
Angiogenesis
What does angiogenesis do?
Increases the number of vessels in a certain area and increases existing vessels to enlarge
Where is angiogensis common?
In the heart when a coronary vessel is occluded (blocked)
What short term regulation dominates in skeletal muscle?
Myogenic
During muscle activity, blood flow increases in direct proportion to the ______
exercise or metabolic activity
Blood flow to the brain is _____ as neurons are intolerant of ischemia (restriction of blood supply to vessels)
Constant
What are the main metabolic controls of the brain?
Decline of pH
increased CO2 or Vasodilation